Clinical and Morphological Features of Focal Adenomyosis

Aleksey A. Shklyar*; Nina B. Paramonova, PhD; Evgeniya A. Kogan, PhD, ScD; Alexander I. Guus, PhD, ScD; Yuliya B. Kurashvili, PhD, ScD; Leila V. Adamyan, PhD, ScD.

Science Center of obstetrics, gynecology and perinatology named after academician V.I. Kulakov, Moscow, Russian Federation

*Corresponding author: Aleksey A. Shklyar, PhD student. Science Center of obstetrics, gynecology and perinatology named after academician V.I. Kulakov. Moscow, Russian Federation. E-mail: doctorshklyar@gmail.com

Published: September 24, 2013

Abstract: 

Background: Adenomyosis is a very real problem encountered in modern gynecology due to the increase in the incidence, severity of the disease, and absence of effective methods of conservative treatment. The aim of the study was to investigate the clinical and morphological features of the focal and diffuse forms of adenomyosis.

Methods and Results: The study involved 70 women who applied to the Center with the diagnosis of ‘adenomyosis’. Examination included transvaginal sonography (TVS), magnetic resonance spectroscopy (MRS), and morphological study of the adenomyotic foci. With a probability of 99%, one can argue that focal adenomyosis (FA) in its clinical features is different from diffuse adenomyosis (DA) in all its major manifestations.

Conclusion: FA has unique morphological characteristics and clinical features. The diagnosis of FA should be based on a complex of clinical and instrumental data in conjunction with morphological process verification. Besides, there are difficulties in the diagnosis of FA, which is a major reason for the incorrect determination of the treatment tactic for patients. However, the application of MRS allows the preoperative identification of the biochemical structure of the focus and determination of its borders, and in the postoperative period, selection of optimal treatment tactics based on the identified morphological features of the removed adenomyotic foci.

Keywords: 
focal adenomyosis; transvaginal sonography; magnetic resonance spectroscopy.
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Int J Biomed. 2013; 3(3):166-169. © 2013 International Medical Research and Development Corporation. All rights reserved.