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Study explores the intricate gut-brain-liver connection and its impact on health
Study reviews the gut-brain-liver axis, revealing the complex interplay between these organs in health and disease and the implications for therapeutic interventions, focusing on how gut microbiota affects liver and brain health.
Study links organic Mediterranean diet to improved male fertility
Researchers in Italy have found that a low-carbohydrate organic Mediterranean diet significantly enhances male fertility by increasing testosterone levels and reducing sperm DNA fragmentation, offering new dietary guidelines for improving male reproductive health.
Women over 50 can safely reduce mammogram frequency after breast cancer surgery
Women 50 or older who de-escalated to less-frequent mammography three years after curative surgery for early-stage breast cancer had similar outcomes to women who received annual mammography, according to results from the Mammo-50 trial presented at the San Antonio Breast Cancer Symposium, held December 5-9, 2023.
Low-risk DCIS patients may safely skip radiotherapy after surgery, study finds
Patients with low-risk ductal carcinoma in situ (DCIS) who skipped adjuvant radiotherapy after breast-conserving surgery had comparable five-year outcomes to those with high-risk DCIS who received adjuvant radiotherapy, according to results from the E4112 clinical trial presented at the San Antonio Breast Cancer Symposium, held December 5-9, 2023.
New insights into how anti-obesity drugs could help prevent kidney disease
Data from Australian researchers could partly explain why a trial of a new drug for diabetes, was recently halted because it was found to be so effective.
Study identifies targetable fusion RNAs in breast cancer
Comprehensive profiling of fusion RNAs present in a large cohort of metastatic breast tumors revealed unique fusion mutations that may be therapeutically targetable, according to results presented at the San Antonio Breast Cancer Symposium, held December 5-9, 2023.
Study unlock secrets of Zika virus's multipurpose enzyme and reveals therapeutic vulnerability
Viruses have limited genetic material-;and few proteins-;so all the pieces must work extra hard. Zika is a great example; the virus only produces 10 proteins.
Women undergoing chemotherapy may not benefit from common fertility protection drug
A new study from Karolinska Institutet in Sweden has found no evidence that a common drug used to protect the ovaries of women undergoing chemotherapy increases their chances of having children after cancer treatment.
New discovery could provide a potential target to treat diabetes
Researchers at Case Western Reserve University and University Hospitals have identified an enzyme that blocks insulin produced in the body-;a discovery that could provide a new target to treat diabetes.
Closing the gender gap in HIV treatment could slash infection rates in Uganda
A study looking at 15 years of HIV transmission and suppression in Uganda reveals how closing gender gaps in treatment could slash infection rates.
Plant-based diets and genetic risk for obesity
The potential link between plant-based dietary patterns (plant-based dietary indices, PDI) and genetic risk of obesity.
How did machine learning models perform in identifying hepatitis in patients with diabetes?
The performance of different machine learning models in detecting hepatitis among people with diabetes.
Cryo-EM reveals TAF15 as potential treatment target for frontotemporal dementia
An international team of researchers including experts at the Indiana University School of Medicine has identified a protein found in the brains of people with frontotemporal dementia (FTD), discovering a new target for potential treatments for the disease.
Fused pancreatic cancer organoid system captures tumor heterogeneity and drug resistance
Pancreatic ductal adenocarcinoma (PDAC), that arises from pancreatic epithelial cells, is the most common form of pancreatic cancer, with a very high mortality rate.
Study identifies new target for fatty liver disease treatment
The global rise in obesity and diabetes is leading to an epidemic in fatty liver disease affecting 20-30 per cent of the world's population.
Repeated mRNA vaccines supercharge immune response against COVID-19, study finds
Study published in Nature Immunology reveals that repeated mRNA COVID-19 vaccinations enhance immune response, especially in previously infected individuals, leading to a diversified and increased number of immune cell clones and a stronger ability to combat various virus strains.
A class of diabetes medications may reduce the risk of colorectal cancer
A groundbreaking study by researchers at Case Western Reserve University suggests a class of medications used to treat type 2 diabetes may also reduce the risk of colorectal cancer (CRC).
Study shows decline in post-surgery opioid prescriptions, but urges continued efforts
Post-surgery pain relief has shifted away from opioid-containing medications over the past seven years, but the downward trend has slowed since 2020, a new study shows.
Groundbreaking 'Gnocchi' map reveals hidden secrets of the human genome
Study presents a genome-wide map, "Gnocchi," constructed from 76,156 human genomes, revealing that non-coding regions rich in regulatory elements are crucial in understanding human traits and diseases.
Is your body out of sync? Study finds organs age at varying rates
Research uncovers that human organs age at varying rates, with some showing accelerated aging compared to chronological age, significantly impacting overall health and disease risk. The study used advanced blood plasma proteomics to analyze organ-specific aging in nearly 5,700 adults, linking it to increased risks of heart failure and Alzheimer's disease.