Morphological Substantiation for the Effectiveness of the Proposed Method of Gastrostomy using a Polypropylene Endoprosthesis

Sergey N. Shurygin, Alexey G. Vaganov, Archil S. Tsulaya, Sarkis A. Asratyan, Ilya V. Sazhin, Aleksandr N. Alimov, Leonid V. Safonov, Dmitriy A. Volkov

International Journal of Biomedicine. 2020;10(1):45-49.
DOI: 10.21103/Article10(1)_OA6
Originally published March 15, 2020


The article discusses the morphological changes in the area of gastrostomy performed by the proposed original method of gastrostomy using an implant  in laboratory animals (rabbits). Morphological changes in the tissues at gastrostomy sites were studied on Days 10 and 20 after the proposed method of gastrostomy, in comparison with the classical Witzel gastrostomy and Depage-Janeway gastrostomy using the GIA stapler. Negative morphological changes in the tissues around gastrostomy sites were revealed in the form of necrosis of the microenvironment and disturbance in microcirculation according to the stagnant type, caused by the damaging effect of the surgical suture material at the microscopic level, the least pronounced when using a polypropylene implant.

gastrostomy • original method • polypropylene mesh • histology
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Received December 31, 2020.
Accepted March 3, 2020.
©2020 International Medical Research and Development Corporation.