International Journal of Biomedicine. 2021;11(2):177-180.
Originally published June 5, 2021
The COVID-19 pandemic has presented challenges to finding effective treatment for lung damage. Medical researchers from different countries recognize the deficiency of pulmonary surfactant (PS) as a significant cause of the alveolar collapse, followed by microatelectasis and severe disturbances in the ventilation-perfusion relationship. Due to the pathophysiological rationale, experimental confirmations, and accumulated clinical experience, the PS preparations can be used to treat patients with severe COVID-19. The article provides a description of a case when ST was successfully used in a patient with severe COVID-19 pneumonia.
- Takano H. Pulmonary surfactant itself must be a strong defender against SARS-CoV-2. Med Hypotheses. 2020 Nov;144:110020. doi: 10.1016/j.mehy.2020.110020.
- Witczak A, Prystupa A, Kurys-Denis E, Borys M, Czuczwar M, Niemcewicz M, Kocik J, Michalak A, Pietrzak A, Chodorowska G, Krupski W, Mosiewicz J, Tomasiewicz K. Acute respiratory distress syndrome (ARDS) complicating influenza A/H1N1v infection--a clinical approach. Ann Agric Environ Med. 2013;20(4):820-2.
- Alekseev AM, Yakovlev AA, Shvechkova MV, Seiliev AA, Volchkov VA, Rosenberg OA. Surfactant therapy for pneumonia and ARDS associated with the A / H1N1 virus. Transbaikalian Medical Bulletin. 2011; 1: 23-27. [Article in Russian].
- Averyanov AV, Klypa TV, Balionis OI, Bychinin MV, Cherniak AV, Troitskiy AV, Trifonova EV. Inhaled surfactant in patients with COVID-19 who took high-flow oxygen: the results of a retrospective analysis. Meditsinskiy sovet = Medical Council. 2020;(17):75-80. doi: 10.21518/2079-701X-2020-17-75-80. [Article in Russian].
- Bautin AE, Avdeev SN, Seyliev AA, Shvechkova MV, Merzhoeva ZM, Trushenko NV, Semenov AP, Lapshin KB, Rozenberg OA. Inhalation surfactant therapy in the integrated treatment of severe COVID-19 pneumonia. Tuberculosis and Lung Diseases. 2020;98(9):6-12. doi: 10.21292/2075-1230-2020-98-9-6-12 [Article in Russian].
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