International Journal of Biomedicine. 2021;11(4):498-504.
Originally published December 10, 2021
Background: The relative frequency of malignant tumors has been reported to have an association with age, gender, and location. The current study is a retrospective study to assess the pattern and relative frequency of different malignant tumors in Najran, Saudi Arabia.
Methods and Results: All patients from both genders were included in the study from June 2014 to May 2019, and data were retrieved from the records of confirmed cancer cases at the departments of pathology. For 5 years, a total of 763 cases [325(42.6%) men and 438(57.4%) women] and 37 types of malignant tumors were diagnosed in Najran. According to the histopathological diagnosis, carcinomas were the most frequent tumors (n=564, 73.9%). According to the affected organ/body system, tumors of the gastrointestinal system were the commonest malignancy, observed in 156 (20.4%) of the patients (91 men and 65 women). Finally, the chi-square test revealed that the frequency of malignant tumors climbed as age increased (P=0.0005).
Conclusion: The relative frequency of several cancers in Najran showed that the most common cancers in both genders are in the following order: gastrointestinal, thyroid, breast, skin and soft tissue cancers, and lymphoma. In addition, women are more affected than men, and increasing age is a risk factor to develop a malignancy.
- Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018;68(6):394-424. doi:10.3322/caac.21492
- Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, Bray F. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA Cancer J Clin. 2021 May;71(3):209-249. doi: 10.3322/caac.21660.
- Popat K, McQueen K, Feeley TW. The global burden of cancer. Best Pract Res Clin Anaesthesiol. 2013;27(4):399-408. doi:10.1016/j.bpa.2013.10.010
- Fidler MM, Bray F, Soerjomataram I. The global cancer burden and human development: A review. Scand J Public Health. 2018 Feb;46(1):27-36. doi: 10.1177/1403494817715400.
- Al-Karawi MA, Mohamed AE. Profile of Cancer in Riyadh Armed Forces Hospital. Ann Saudi Med. 1995;15(4):424-424. doi:10.5144/0256-4947.1995.424a
- Bazarbashi S, Al Eid H, Minguet J. Cancer Incidence in Saudi Arabia: 2012 Data from the Saudi Cancer Registry. Asian Pac J Cancer Prev. 2017 Sep 27;18(9):2437-2444. doi: 10.22034/APJCP.2017.18.9.2437.
- Chaudhri E, Fathi W, Hussain F, Hashmi SK. The Increasing Trends in Cases of the Most Common Cancers in Saudi Arabia. J Epidemiol Glob Health. 2020 Dec;10(4):258-262. doi: 10.2991/jegh.k.200515.001.
- Hussain F, Iqbal S, Mehmood A, Bazarbashi S, ElHassan T, Chaudhri N. Incidence of thyroid cancer in the Kingdom of Saudi Arabia, 2000-2010. Hematol Oncol Stem Cell Ther. 2013;6(2):58-64. doi:10.1016/j.hemonc.2013.05.004
- Alyami HS. Knowledge, awareness and recommendations of cancer among the healthcare professionals in Najran region, Saudi Arabia: A cross-sectional study. Biomed Res. 2020;31(2):48-52.
- Logroscino G, Marin B, Piccininni M, Arcuti S, Chiò A, Hardiman O, Rooney J, Zoccolella S, Couratier P, Preux PM, Beghi E; for EURALS. Referral bias in ALS epidemiological studies. PLoS One. 2018 Apr 16;13(4):e0195821. doi: 10.1371/journal.pone.0195821.
- Al-Shahrani ZS, Al-Rawaji AI, Al-Madouj AN, Hayder MS. Saudi Cancer Registry: Cancer Incidence Report Saudi Arabia 2014. Saudi Heal Counc Riyadh, Saudi Arab. 2017;1(1):1-82.
- Alshammari FD, Ahmed HG, Alawad GM, Alshammary MM, Alrashdi AG, Alrashedi SA, et al. Epidemiological indicators of Cancer in North Saudi Arabia: A population-based Survey. Int J Biomed Res. 2015;6(9):674-682. doi:10.7439/ijbr.v6i9.2457
- Global Cancer Observatory. Saudi Arabia - Global Cancer Observatory. WHO GCO. 2020;1(1):1-2.
- Koriech OM, Al-Kuhaymi R. Profile of cancer in Riyadh Armed Forces Hospital. Ann Saudi Med. 1994;14(3):187-194. doi:10.5144/0256-4947.1994.187
- Torre LA, Islami F, Siegel RL, Ward EM, Jemal A. Global cancer in women: Burden and trends. Cancer Epidemiol Biomarkers Prev. 2017;26(4):444-457. doi:10.1158/1055-9965.EPI-16-0858
- El-Akkad SM, Amer MH, Lin GS, Sabbah RS, Godwin JT. Pattern of cancer in Saudi Arabs referred to King Faisal Specialist Hospital. Cancer. 1986 Sep 1;58(5):1172-8. doi: 10.1002/1097-0142(19860901)58:5<1172::aid-cncr2820580533>3.0.co;2-1.
- Koriech OM, ALKUHAYMI R. Thyroid-Cancer Clinicopathological Study of 113 Cases in Saudi-Arabia. Saudi Med J. 1988;9(2):188-193.
- Basha S, Roshan NM, Al-Thomali Y, Al Shamrani AS. The Prevalence of Oral Cancer in Saudi Arabia – A Systematic Review. Ann Med Heal Sci Res. 2019;9(2):553-557.
- Jazieh AR, Algwaiz G, Alshehri SM, Alkattan K. Lung Cancer in Saudi Arabia. J Thorac Oncol. 2019;14(6):957-962. doi:10.1016/j.jtho.2019.01.023
- Bawazir A, Al-Zamel N, Amen A, Akiel MA, Alhawiti NM, Alshehri A. The burden of leukemia in the Kingdom of Saudi Arabia: 15 years period (1999-2013). BMC Cancer. 2019;19(1):1-10. doi:10.1186/s12885-019-5897-5
- Almohideb M. Epidemiological Patterns of Skin Disease in Saudi Arabia: A Systematic Review and Meta-Analysis. Dermatol Res Pract. 2020 Oct 27;2020:5281957. doi: 10.1155/2020/5281957.
- Albasri AM, Borhan WM. Histopathological pattern of skin cancer in Western region of Saudi Arabia. An 11 years experience. Saudi Med J. 2018 Oct;39(10):994-998. doi: 10.15537/smj.2018.10.22679.
- Alwunais KM, Ahmad S. Pattern of skin cancer at Dammam Medical Complex in Dammam, Saudi Arabia. J Dermatology Dermatologic Surg. 2016;20(1). doi:10.1016/j.jdds.2015.06.002
- Albasri AM, Ansari IA. Pattern of cancers in adolescent and young adults.: A 15-year retrospective study at King Fahad Hospital, Al-Madinah Al-Munawwarah, Saudi Arabia. Saudi Med J. 2021 Apr;42(4):449-453. doi: 10.15537/smj.2021.42.4.20210028.
Received October 30, 2021.
Accepted November 11, 2021.
©2021 International Medical Research and Development Corporation.