Left Ventricular Mass Appropriateness in Hypertensive Patients with Metabolic Syndrome

ORIGINAL ARTICLE
Nigora Z. Srojidinova, PhD*

Republican Center of Cardiology, Tashkent, Uzbekistan

*Corresponding author: Nigora Z. Srojidinova, PhD. The Republican Specialized Center of Cardiology, Tashkent, Uzbekistan. E-mail: nigora5505@gmail.com

Published: September 12, 2016.  DOI: 10.21103/Article6(3)_OA2

Abstract: 

The objective of this study was to evaluate the frequency of inappropriate left ventricular (LV) mass (iLVM) and factors associated with iLVM in hypertensive patients with metabolic syndrome (MetS). The study included 178 male patients (mean age 45.9±10.5 yrs) with hypertension (HT) and MetS. iLVM  in HT patients with MetS was associated with LV diastolic dysfunction  and an intensity of vascular remodeling process.  Hyperinsulinemia contributes to LVM appropriateness, which aggravates the cardiovascular remodeling with development of the significant LV diastolic dysfunction and endothelium dysfunction.   

Keywords: 
hypertension; metabolic syndrome; left ventricular hypertrophy; inappropriate left ventricular mass
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Int J Biomed. 2016;6(3):170-173. © 2016 International Medical Research and Development Corporation. All rights reserved.