The Relationship between Morphological and Functional Features of Preterm Placentas and the Results of Bacteriological Examination of the Discharge from the Cervical Canal of Women with Preterm Birth

Agamurad A. Orazmuradov, Igor N. Kostin, PhD, Marina B. Khamoshina, Sergey V. Apresyan, Setonde Romeo D. Konnon, Alexandra A. Gavrilova, Anna N. Parygina, Gayane A. Arakelyan, Irina V. Savenkova, Aleksey A. Lukaev

International Journal of Biomedicine. 2019;9(4):313-319.
DOI: 10.21103/Article9(4)_OA8
Originally published December 15, 2019


The aim of this study was to determine the relationship between the morpho-functional features of placentas from preterm births (PBs) with the results of bacteriological examination of the discharge from the cervical canal in women with spontaneous preterm birth (SPB).
The study included 227 pregnant women at gestational age between 28 and 36 weeks and 6 days, who underwent examination in the period from 2017 to 2018. Depending on the gestational age, they were divided into 3 groups.      In general, a strong relationship was found between the presence of pathological changes in placentas and the presence of opportunistic flora in women (R=0.722, P<0.001). The constructed mathematical models make it possible to determine, with a high degree of certainty, the main bacteria for all the studied groups of pregnant women, thereby identifying the risk group of women at the stage of pregnancy planning, predicting complications and increasing the possibility of deliver a full term baby.

preterm birth • placenta • opportunistic flora • placental insufficiency
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Received October 1, 2019.
Accepted November 11, 2019.
©2019 International Medical Research and Development Corporation.