Intracranial Venous Pressure as a Possible Determinant of Mental Regulation

Alexander G. Kruglov, PhD, ScD, Georgiy Y. Gebel, PhD, ScD†, Alexander Y. Vasilyev, PhD, ScD*

Moscow State University of Medicine and Dentistry, Moscow, Russian Federation

*Corresponding author: Prof. Alexander Y. Vasilyev, PhD, ScD, Head of Radiology Department, Moscow State University of Medicine and Dentistry, 15 Aviaconstructor Mil str., housing 1, apt. 70, 109431, Moscow, Russian Federation. Tel: 7-495-6110177.


The article deals with the mechanisms of cerebral venous blood flow (CVB). CVB is discussed as the equivalent of initiation of neuron chain activity, providing the mental activity of a person. Venous cerebral hemodynamics and the activity of neuron chains are considered as synergistic components of the mechanism of target achievement through the information determination of physiologic processes. The concept of "motivation gradient" (MG) is introduced, as a vector initiator of selfregulation, with a difference in sample parameters in starting (present) and final (target) stages. Decreasing subjective temporal flow is argued to have an opposite vector to MG. It reaches the zero value at the point of parametric alignment of MG. As imbalance, a feeling of dissatisfaction and other deficit problems, i.e. gradient conditions, may develop through the full spectrum of requirements (physical, social, etc), the concept of MG is proposed for usage in a wide range of applications, both in physiology and in psychology. 

target, information determination, neuron chains, cerebral venous blood flow, motivation gradient, adaptable dynamic, subjective time, parametric alignment, homeostatic balance

1. Labory A. Regulation of metabolic processes. Moscow: Medicine, 1980.

2. Lerman VP. Cerebral circulatory disorders in intracranial tumors.  Minsk, 1976.

3. Moskalenko YE, Weinstein GB, Demchenko IT, Kislyakov YY, Krivchenko AI. Intracranial hemodynamics.  Leningrad: Nauka, 1975.

4. Moskalenko YE, Weinstein HB. The role of intracranial veins in the cerebral blood flow regulation mechanism.  In: Proceeds of the International Symposium on the regulation of capacitative vessels. Moscow: Medicine, 1977. p 120-120.

5. Moskalenko YE. Functional stability of the cerebral circulation.  Physiological Journal 1978; 64: 589-597.

6. Rubinstein SL. Fundamentals of General Psychology. Saint Petersburg: Piter, 2003.

7. Shidlovsky VA, Vezloyaschev DV, Lischuk VA, Ledenev VI, Nelyudova IV, Sadoyan DG. Biophysical properties of an isolated cardiovascular system. Krovoobraschenije 1976; 5: 29-36.

8. Shvyrkov VB. Introduction to objective psychology. Neural basis of psychology.  Moscow: Moscow Institute of Psychology of RAS, 1995.

9. Tkachenko BI. Venous circulation. Leningrad, 1979.

Download Article

Int J Biomed. 2011; 1(4):245-248. © 2011 International Medical Research and Development Corporation. All rights reserved.