Features of Subtransaminasemia Interpretation

Iskandar R. Mavlyanov PhD, ScD¹, Zavkiddin M. Orziyev, PhD, ScD², Farmon E. Nurbayev, PhD², Erkin E. Safronov²

¹Tashkent Medical Academy, Tashkent, Uzbekistan

²Bukhara State Medical Institute, Bukhara, Uzbekistan


Alanine and aspartate aminotransferase levels often increase, without any accompanying clinical signs of liver disease. This biochemical phenomenon has increasingly begun to attract the attention of specialists because of the frequency of its occurrence, which is the reason for the rising recognition of the reality of this problem. In fact, determination of the increased level of transaminases at first suggests its relation to some liver disease, despite the absence of its clinical manifestations. Frequently, this is followed by a long process of looking for various liver diseases by both the doctor and patient. In principle, this approach is justified and undisputed. However, the question that arises is whether this tactic is always acceptable! If not, what alternative is to be sought for in such cases? These and other unresolved issues were the reasons that prompted this study, to take a fresh look at this rather old problem. 

Alanine aminotransferase, aspartate aminotransferase, transaminasemia
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Int J Biomed. 2011;1(4):249-252.©2012 International Medical Research and Development Corporation. All rights reserved