Vitamin D Deficiency Manifested by Premature Ventricular Complexes from RVOT: A Report on Two Twins

CASE REPORT
Gabriel Cismaru, Cecilia Lazea, Daniela Iacob, Simona Cainap

 
International Journal of Biomedicine. 2021;11(2):220-223.
DOI: 10.21103/Article11(2)_CR4
Originally published June 5, 2021

Abstract: 

Vitamin D receptor is present in almost every cell of the body. Although some studies have suggested that values >30ng/ml would be sufficient, there is no consensus on the optimal values of serum vitamin D. Vitamin D deficiency can lead to “benign” manifestations, such as back pain, joint pain, fatigue, and heavy sweating. Premature ventricular contractions (PVCs) originating from the right ventricular outflow tract (RVOT) are considered “benign,” as they occur in patients without structural heart disease and their exact cause remains unknown. We describe the case of a 10-year-old boy with frequent PVCs and vitamin D deficiency that was corrected after vitamin D supplementation. On the contrary, his twin brother had normal serum vitamin D and no PVCs. The disappearance of PVCs occurred after treatment with vitamin D 2000 IU/day.

Keywords: 
right ventricular outflow tract • twins • vitamin D • premature ventricular contractions • 24-hour Holter ECG
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