Experimental Substantiation of Application of Autoplasma to Reduce Inflammatory Response to Implants in Herniology

ORIGINAL ARTICLE
Serhiy H. Hryvenko, Yuriy A. Semenov, Mariia A. Behma, Abhijit Mahanta, Tamila E. Usmanova, Andrej A. Dovgan

 
International Journal of Biomedicine. 2022;12(1):134-137.
DOI: 10.21103/Article12(1)_OA14
Originally published March 10, 2022

Abstract: 

The article represents an experimental assessment of the effectiveness of the author's method of processing polypropylene mesh implants during their implantation in the tissue of the anterior abdominal wall  (Patent of Ukraine No. 146133). It has been demonstrated that the use of the proposed new technology for processing polypropylene mesh implants with a biocompatible component, being a simple, safe, and effective method, optimizes reparative processes in the peri-implantation zone without deteriorating the mechanical properties of mesh implants (MI). All the discovered effects make it possible to increase biocompatibility and improve the survival rate of MI. The thickness of the inflammatory shaft around the elements of MI was significantly decreased, on average, by 28.4% (P<0.05) when using autogenous blood plasma.

Keywords: 
polypropylene • anterior abdominal wall • mesh implants • autogenous blood plasma
References: 
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Received January 13, 2022.
Accepted February 11, 2022.
©2022 International Medical Research and Development Corporation.