Potential Anticoagulant Activity of Thymus atlanticus Leaves Part in vitro on Normal Plasma Samples

ORIGINAL ARTICLE
Mothana Abdullah Elhussein, Albara Ahmad, Yousif Mohammed Elmosaad, Hisham Ali Waggiallah

 
International Journal of Biomedicine. 2022;12(2):299-302.
DOI: 10.21103/Article12(2)_OA18
Originally published June 5, 2022

Abstract: 

The purpose of this study was to evaluate the anticoagulant activity of Thymus atlanticus leaves.
Methods and Results: This cross-sectional study was carried out in Khartoum state from March 2021 to June 2021. This study comprised 60 healthy volunteers (40% men and 60% women) aged 19-25 years. Activated partial thromboplastin time (APTT) and prothrombin time (PT) were evaluated in the blood plasma with different amounts of Thymus atlanticus leaves using Coatron M1 (TECO Medical Devices). Thymus atlanticus leaves considerably lengthened APTT and PT in all tested concentrations.  Furthermore, only the APTT test at a concentration of 5.17 μl revealed a significant difference in the anticoagulant activity of Thymus atlanticus leaves between males and females. No correlation between age and anticoagulant activity of Thymus atlanticus leaves on PT and APTT in the study was found.

Keywords: 
activated partial thromboplastin time • prothrombin time • Thymus atlanticus
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Received February 16, 2022.
Accepted April 5, 2022.
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