Leukocyte Shift Index in Purulent-Inflammatory Pathology of the Middle Ear in Children in the Age Aspect

Nadezhda E. Kuznetsova, Maria N. Ponomareva, Tatiana B. Kuznetsova, Polina A. Luntovskaya

International Journal of Biomedicine. 2022;12(3):466-469.
DOI: 10.21103/Article12(3)_ShC1
Originally published September 5, 2022


The aim of the study was a comparative analysis of the blood value of the leukocyte shift index (LSI) in acute suppurative otitis media (ASOM) and chronic suppurative otitis media (CSOM), depending on the age of children.
Methods and Results: This study included 100 children (62 boys and 38 girls)  aged 1-16 years who were diagnosed with ASOM and CSOM. The mean age of all patients was 7.59±0.50 years. Group 1 included 50 patients (30 boys and 20 girls) with ASOM. Group 2 included 50 patients (20 boys and 30 girls) with CSOM. As a marker for determining the activity of the inflammatory process, we chose LSI, calculated taking into account the parameters of the general blood test. LSI levels ​​in the patients of Group 1 and Group 2 were 2.08±0.23 and 1.51±0.16, respectively (P=0.0446). The results obtained indicate that in children with mean age of 3.44±0.31 years, the LSI level of 2.08±0.23 can suggest the formation of ASOM. In children with mean age of 11.56±0.46 years, the LSI level of 1.51±0.16 can suggest the formation of CSOM.
Conclusion: The proposed method for predicting CSOM in children has enough grounds for clinical application in practical health care.

chronic suppurative otitis media • leukocyte shift index • children
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Received June 1, 2022.
Accepted July 7, 2022.
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