International Journal of Biomedicine. 2023;13(3):137-142.
Originally published September 5, 2023
Background: All types of chromosomal aberrations have an impact on the development of dermatoglyphs, which changes both their quantitative and qualitative characteristics. This study aims to compare the quantitative characteristics of dermatoglyphs between individuals with Down syndrome and those with normal karyotypes in the Kosova Albanian population.
Methods and Results: The quantitative characteristics of digitopalmar dermatoglyphs were analyzed on 104 individuals (54 men and 50 women) with Down syndrome from Kosova's Albanian population. The dermatoglyphs of 403 Albanians from Kosova with normal karyotypes (the control group) were also analyzed quantitatively. Using the method devised by Cummins and Midlo, dermatoglyph traces were obtained and analyzed. We analyzed the quantitative features of both the dermatoglyphs of the fingers and the dermatoglyphs of the palms of the hands. Moorhead and Seabright's peripheral blood culture technique was utilized to analyze the karyotypes of individuals with Down syndrome.
A total of 40 dermatoglyphic variables were analyzed. When the quantitative dermatoglyphic features of men with Down syndrome and the control group were compared, significant differences were discovered in 20 of the dermatoglyphic variables. Significant differences were discovered in 21 of the dermatoglyphic variables when the features of women with Down syndrome and the control group were compared. One of the most distinctive characteristics of Down syndrome was the breadth of the atd angle, which should be taken into consideration. Compared to the control group's males and females, the males and females with Down syndrome exhibit wider atdT angles (161.91° vs. 92.60° [P<0.0001] and 165.48° vs. 94.75° [P<0.0001], respectively).
Conclusion: The size of atd angles is the factor that most closely identifies people with Down syndrome.
- Sharma A, Sood V, Singh P, Sharma A. Dermatoglyphics: A review on fingerprints and their changing trends of use. CHRISMED J Health Res. 2018;5(3):167-172.
- Nayak SB, Velan J, Shern NL, Zoung LF, Jeyarajan A, Aithal AP. Correlation between dermatoglyphic pattern of right thumb; learning methodologies; and academic performance of medical students. J Datta Meghe Inst Med Sci Univ. 2017;12(3):177-180.
- Sharma M K, Jhawar P, Sharma H, Sharma S, Kalavatia I. Dermatoglyphics an attempt to predict Downs syndrome. Int J Biol Med Res. 2012;3(2):1631-1635.
- Masjkey D, Bhattacharya S, Dhungel S, Jha CB, Shrestha S, Ghimire SR, Rai D. Utility of phenotypic dermal indices in the detection of Down syndrome patients. Nepal Med Coll J. 2007 Dec;9(4):217-21.
- Ghodsi Z, Shahri N M, Ahmadi S K. Quantitative and qualitative study of Dermatoglyphic patterns in albinism. Current Research Journal of Biological Sciences. 2012;4(4):385-388.
- Rosa A, Arquimbau R, Fananas L. Quantitative and qualitative palmar dermatoglyphics in the Mediterranean population of Delta de L’ebre (Spain). Int J Anthropol. 1998;13:89-96.
- Cvjeticanin M, Jajic Z, Burgic N. Quantitative analysis of digitopalmar dermatoglyphics in forty female ankylosing spondylitis patients. International Journal of Current Research. 2018;10(09):73791-73798.
- Cvjeticanin M, Jajic Z, Hadzigrahic N. Quantitative analysis of digitopalmar dermatoglyphics in fifty female psoriatic monoarthritis patients. Imperial Journal of Interdisciplinary Research (IJIR). 2016; 2:10101-10105.
- Tarca A. Dermal prints pathology in Down syndrome. JURNAL DE MEDICINĂ PREVENTIVĂ. 2001;9(1):18- 23.
- Hassanzadeh N M, Raoofian R, Abutorabi R, Hosseini HB. Dermatoglyphic assessment in Down and Klinefelter syndrome. Jran J Med Sci. 2007;32(2):105-109.
- Sontakke BR, Ghosh SK, Pal AK. Dermatoglyphics of fingers and palm in Klinefelter's syndrome. Nepal Med Coll J. 2010 Sep;12(3):142-4.
- Bhalla AK, Marwaha RK, Sharma A, Trehan A, Muralidharan R, Bagga R. Dermatoglyphics in Turner syndrome. Int J Anthropol. 2005;20(1-2):111-125.
- Theisen A, Shaffer LG. Disorders caused by chromosome abnormalities. Appl Clin Genet. 2010 Dec 10;3:159-74. doi: 10.2147/TACG.S8884.
- Danopoulos S, Deutsch GH, Dumortier C, Mariani TJ, Al Alam D. Lung disease manifestations in Down syndrome. Am J Physiol Lung Cell Mol Physiol. 2021 Nov 1;321(5):L892-L899. doi: 10.1152/ajplung.00434.2020.
- Kolgeci S, Kolgeci J, Azemi M, Shala-Beqiraj R, Gashi Z, Sopjani M. Cytogenetic study in children with down syndrome among kosova Albanian population between 2000 and 2010. Mater Sociomed. 2013;25(2):131-5. doi: 10.5455/msm.2013.25.131-135.
- Kolgeci S, Kolgeci J, Azemi M, Daka A, Shala-Beqiraj R, Kurtishi I, Sopjani M. Dermatoglyphics and Reproductive Risk in a Family with Robertsonian Translocation 14q;21q. Acta Inform Med. 2015 Jun;23(3):178-83. doi: 10.5455/aim.2015.23.179-183.
- Santhosh K. Role of Dermatoglyphics as a Diagnostic Tool in Syndromes and Systemic Disorders. Int J Dentistry Oral Sci. 2021;08(5):2390-2400
- Gasiorowski A, Hajn V. Dermatoglyphic analysis of palm prints by the method according to Cummins et Midlo. Biologica. 2002;39(40):153-161.
- Verma RS, Babu A, Hill G. Human Chromosomes: Principles and Techniques. Second Edition, New York, 1995:72-133.
- Hossain MM, Ashrafuzzaman M, Jahan I, Lugova H, Samad N, Das P, Haque M. An Adaptive Approach to Detection of Dermatoglyphic Patterns of Bangladeshi People with Down Syndrome Using Fingerprint Classification. Advances in Human Biology. 2021;11(3):255-261
- Cam FS, Gul D, Tunca Y, Fistik T. Analysis of the dermatoglyphics in Turkish patients with Klinefelter’s syndrome. Hereditas. 2008;145:163-166.
- Matsuyama N, Ito Y. The frequency of fingerprint type in parents of children with Trisomy 21 in Japan. J Physiol Anthropol. 2006 Jan;25(1):15-21. doi: 10.2114/jpa2.25.15.
- PENROSE LS. The distal triradius t on the hands of parents and sibs of mongol imbeciles. Ann Hum Genet. 1954 Jul;19(1):10-38. doi: 10.1111/j.1469-1809.1954.tb01260.x.
- Plato CC, Cereghino JJ, Steinberg FS. Palmar dermatoglyphics of Down's syndrome: revisited. Pediatr Res. 1973 Mar;7(3):111-8. doi: 10.1203/00006450-197303000-00002.
- Parveen R, Rahman MS, Ahmed M, Azim MA, Momena Z, Salman MN. Dermatoglyphic Assessment in Male Down Syndrome. Community Based Medical Journal. 2002;11(2):144–151.
Received July 21, 2023.
Accepted August 19, 2023.
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