Oral Mucosal Changes in Acrylate Prosthesis Wearers Among Diabetic Patients: A Review Article

Erejeta Deva Kurshumliu, Gordana Kovacevska, Kujtim Shala, Blerta Musliu Krasniqi, Fisnik Kurshumliu

International Journal of Biomedicine. 2023;13(4):221-227.
DOI: 10.21103/Article13(4)_RA4
Originally published December 5, 2023


Diabetes mellitus (DM) is one of the significant health problems in the world.  Diabetes affects most parts of the human organism, and the oral cavity is no exception. Among oral manifestations related to DM are dry mouth, tooth decay, periodontal disease, gingivitis, oral candidiasis, burning mouth syndrome, disorders of taste, oral lichen planus, geographic tongue, fissured tongue, delayed wound healing, increased incidence of infection, salivary dysfunction and neurosensory disorders. According to the literature, edentulous patients are more likely to have DM in comparison to the nondiabetic population. The effect of total prostheses on the oral mucosa (OM) has been the subject of many scientific studies. This study aimed to investigate existing evidence related to changes in the OM in DM patients who are wearers of total acrylic prostheses.
Based on the reviewed literature, changes in the OM are much more pronounced in DM patients wearing acrylate prostheses and are caused by severe inflammation and delayed keratinization. A total acrylate prosthesis introduces additional trauma, inflammation, and stress in DM patients.

diabetes mellitus • acrylate prosthesis • oral mucosa • cytological changes
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Received August 12, 2023.
Accepted September 25, 2023.
©2023 International Medical Research and Development Corporation.