Application of Non-Invasive Methods in the Treatment of White Spot Lesions in Children: A Review Article

Blerta Krasniqi, Meri Pavlevska, Erejeta Deva Kurshumliu, Blerta Latifi Xhemaili,Teuta Kutllovci

International Journal of Biomedicine. 2023;13(4):228-235.
DOI: 10.21103/Article13(4)_RA5
Originally published December 5, 2023


This comprehensive review of 25 studies on white spot lesion (WSL) treatment in children highlights the effectiveness of resin infiltration (RI) and the potential of casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) as prominent treatment options. These findings are underscored by comparative studies, emphasizing the importance of long-term effects and age-specific considerations in treatment planning. The diversity in study types and diagnostic methods underscores the need for personalized approaches to WSL management. While common conclusions emerge, such as the efficacy of CPP-ACP and RI, contrasting findings remind us of the complexity of WSL management. The call for further research, particularly long-term studies, indicates the evolving nature of this field and the need for refining treatment protocols. Moreover, these studies emphasize the significance of conservative approaches, including regular oral hygiene practices and minimally invasive interventions, as integral components of a holistic WSL treatment strategy.

white spot lesion • resin infiltration • casein phosphopeptide-amorphous calcium phosphate • fluoride-based treatment • remineralization
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Received October 9, 2023.
Accepted November 23, 2023.
©2023 International Medical Research and Development Corporation.