Superficial Thrombophlebitis of Great Saphenous Vein Following Vaccine

Jose Maria Pereira de Godoy, Ana Carolina Pereira de Godoy, Livia Maria Pereira de Godoy, Maria de Fatima Guerreiro Godoy

For citation: Pereira de Godoy JM, Pereira de Godoy AC, Pereira de Godoy LM, Guerreiro Godoy MF. Superficial Thrombophlebitis of Great Saphenous Vein Following Vaccine. International Journal of Biomedicine. 2024;14(2):357-358. doi:10.21103/Article14(2)_CR6
Originally published June 5, 2024


This paper reports on the occurrence of thrombose of the left great saphenous vein (GSV) soon after being given the AstraZeneca vaccine and two recurrent events within three days after the suspension of the anticoagulant. A 53-year-old patient had superficial thrombophlebitis of the GSV in the left leg three days after taking the second dose of the AstraZeneca vaccine for COVID-19 and initiated treatment with rivaroxaban (XareltoTM) 15 mg twice a day, subsequently increasing to 20 mg. After 45 days, the patient contracted dengue and stopped taking the anticoagulant. Two days later, the patient had another thrombosis in the left GSV. The patient is currently in outpatient care with a prophylactic dose of 10mg/day of anticoagulant and undergoes evaluations at three-month intervals. The result of our study is a rare event.

superficial thrombophlebitis • great saphenous vein • vaccine
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Received April 10, 2024.
Accepted May 18, 2024.
©2024 International Medical Research and Development Corporation.