Prognostic Value of Melatonin in Patients with Chronic Obstructive Pulmonary Disease

Andrey V. Budnevsky, Sergey N. Avdeev, Evgeniy S. Ovsyannikov, Karina V. Vostrikova, Sofiya A. Budnevskaya, Avag G. Kitoyan

For citation: Budnevsky AV, Avdeev SN, Ovsyannikov ES, Vostrikova KV, Budnevskaya SA, Kitoyan AG. Prognostic Value of Melatonin in Patients with Chronic Obstructive Pulmonary Disease. International Journal of Biomedicine. 2024;14(2):227-230. doi:10.21103/Article14(2)_RA3
Originally published June 5, 2024


The article outlines a detailed examination of multiple scientific studies investigating how melatonin affects COPD's advancement and growth. The severity of oxidative stress in COPD, a complex disease with multiple factors, is significantly reduced by melatonin by activating intracellular antioxidants, as suggested by the data acquired. Considering the available data, we can conclude that melatonin has a protective role against oxidative stress in COPD patients in addition to regulating the circadian rhythm.

COPD • oxidative stress • reactive oxygen species • melatonin

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Received April 17, 2024.
Accepted May 27 2024.
©2024 International Medical Research and Development Corporation.