Silver in Wound and Trophic Ulcer Treatment: A Modern View of the Problem

Serhiy H. Hryvenko, Aleksander A. Golomidov, Sydyk A. Sidikov, Manvel S. Margarian, Madina R. Bostanova, Zaineb I. Salpagarova

For citation: Hryvenko SH, Golomidov AA, Sidikov SA, Margarian MS, Bostanova MR, Salpagarova ZI. Silver in Wound and Trophic Ulcer Treatment: A Modern View of the Problem. International Journal of Biomedicine. 2024;14(2):240-245. doi:10.21103/Article14(2)_RA6
Originally published June 5, 2024


This review presents published data on the history of use, mechanism of action, and effectiveness of silver and silver-based drugs in surgical practice. A literature search was carried out using PubMed, EMBASE, Google Scholar, and E-Library databases. Analysis of available literature data convincingly demonstrates the effectiveness of silver nanocomposites as antibacterial and anti-inflammatory agents. The demonstrated antimicrobial property of silver nanoparticles (AgNPs) against various antibiotic-resistant bacteria is especially significant for clinical use. Silver nanoparticles have clinically proven effective in treating wounds and trophic ulcers.

silver • silver nanoparticles • wound • trophic ulcer
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Received March 12, 2024.
Accepted May 25, 2024.
©2024 International Medical Research and Development Corporation.