Second Fatal Case of Infective Endocarditis caused by Gemella bergeriae

Aijan Ukudeeva, MD¹; Hal K. Hawkins, MD, PhD¹,²; Masood Ahmad, MD²; Peerawut Deeprasertkul, MD²; Liliana Rincon, MD²; Brandon K. Kimbrel, BS²; David H. Walker MD²

¹Shriners Burns Hospital for Children, Galveston, ²University of Texas Medical Branch; Galveston, TX, USA

*Corresponding author: Aijan Ukudeeva, MD, MS. Shriners Burns Hospital for Children, Galveston, TX, USA. E-mail: draijan@yahoo.com

Published: March 17, 2017.  doi: 10.21103/Article7(1)_CR1

Abstract: 

Our case illustrates a fatal course of infection with Gemella bergeriae endocarditis that was complicated by cardiogenic shock due to perforation of the mitral valve with severe mitral regurgitation, extension of infection into the myocardium adjacent to the mitral valve, and coronary sinus thrombosis.

Keywords: 
Gemella bergeriae ● infective endocarditis ● mitral valve ● cardiogenic shock
References: 

1. Pant S, Patel NJ, Deshmukh A, Golwala H, Patel N, Badheka A, et al. Trends in infective endocarditis incidence, microbiology, and valve replacement in the United States from 2000 to 2011. J Am Coll Cardiol. 2015; 65(19):2070-6. doi:10.1016/j.jacc.2015.03.518
2. Griffin MR, Wilson WR, Edwards WD, O'Fallon WM, Kurland LT. Infective endocarditis. Olmsted County, Minnesota, 1950 through 1981. JAMA. 1985; 254(9):1199-202.
3. Habib Г, Hoen B, Tornos P, Thuny F, Prendergast B, Vilacosta I, et al.; ESC Committee for Practice Guidelines. Guidelines on the prevention, diagnosis, and treatment of infective endocarditis (new version 2009): the Task Force on the Prevention, Diagnosis, and Treatment of Infective Endocarditis of the European Society of Cardiology (ESC). Endorsed by the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) and the International Society of Chemotherapy (ISC) for Infection and Cancer. Eur Heart J. 2009; 30(19):2369-413. doi: 10.1093/eurheartj/ehp285.
4. Yew HS, Murdoch DR. Global trends in infective endocarditis epidemiology. Curr Infect Dis Rep. 2012;14(4):367-72.doi: 10.1007/s11908-012-0265-5.
5. Collins MD, Hutson RA, Falsen E, Sjöden B, Facklam RR. Gemella bergeriae sp. nov., isolated from human clinical specimens. J Clin Microbiol. 1998;36(5):1290–3.
6. Logan LK, Zheng X, Shulman S. Gemella bergeriae endocarditis in a boy. Pediatr Infect Dis J. 2008;27(2):184-6. doi: 10.1097/INF.0b013e31815b1af0.
7. Hussain K, Abubaker J, Al Deesi ZO, Ahmed R. Unreported neurological complications of Gemella bergeriae infective endocarditis. BMJ Case Rep. 2014; pii: bcr2014204405. doi: 10.1136/bcr-2014-204405.
8. Elsayed S, Zhang K. Gemella bergeriae endocarditis diagnosed by sequencing of rRNA genes in heart valve tissue. J Clin Microbiol. 2004;42(10):4897–900.
9. Pachirat O, Watt G, Pussadhamma B. First Case of Tricuspid Valve Endocarditis Caused by Gemella bergeri. Case Rep Med. 2015;2015:704785. doi: 10.1155/2015/704785.
10. Purcell LK, Finley JP, Cohen R, Lovgren M, Halperin SA. Gemella species endocarditis in a child. Can J Infect Dis. 2001;12(5):317–20.
11. Stroup JS. Bransteitter BA, Reust R. Infective endocarditis caused by Gemella species. Infect Dis Clin Pract. 2007;15(3):203-5.
12. Vasishtha S, Isenberg HD, Sood SK. Gemella morbillorum as a cause of septic shock. Clin Infect Dis. 1996; 22(6):1084-6.
13. Virgilio E, Chieco PA. Sixth case of infective endocarditis caused by Gemella bergeri. Braz J Infect Dis. 2014;18(4):467.doi: 10.1016/j.bjid.2014.05.002.
14. Zakir RM, Al-Dehneh A, Dabu L, Kapila R, Saric M. Mitral bioprosthetic valve endocarditis caused by an unusual microorganism, Gemella morbillorum, in an intravenous drug user. J Clin Microbiol. 2004; 42(10):4893-6.
15. Ruoff K. Aerococcus, Abiotrophia, and other infrequently isolated aerobic catalase-negative, gram-positive cocci. In: Murray PR, Baron EJ, Jorgensen JH, Pfaller MA, Yolken RH, editors. Manual of clinical microbiology. 8th ed. American Society for Microbiology, Washington, D.C. 2003:434-444.
16. Collins MD, Rodriguez Jovita M, Foster G, Sjödén B, Falsen E. Characterization of a Gemella-like organism from the oral cavity of a dog: description of Gemella palaticanis sp. nov. Int J Syst Bacteriol. 1999;49 Pt 4:1523–6.
17. Hoyles L, Foster G, Falsen E, Collins MD. Characterization of a Gemella-like organism isolated from an abscess of a rabbit: description of Gemella cunicula sp. nov. Int J Syst Evol Microbiol. 2000;50 Pt 6:2037–41.
18. Woo PC, Lau SK, Fung AM, Chiu SK, Yung RW, Yuen KY. Gemella bacteremia characterized by 16S ribosomal RNA gene sequencing. J Clin Microbiol. 2003;56(9):690–3.
19. Al-Hujailan G, Lagacé-Wiens P. Mechanical valve endocarditis caused by Gemella morbillorum. J Med Microbiol. 2007;56(Pt 12):1689-91. 20. Al Soub H, El-Shafie SS, Al-Khal AL, Salam AM. Gemella morbillorum endocarditis. Saudi Med J. 2003;24(10):1135–7.

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International Journal of Biomedicine. 2017;7(1):63-66. © 2017 International Medical Research and Development Corporation. All rights reserved.