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New research shows promise for urine-based test to detect ovarian cancer

Rss Feed - Mon, 02/12/2024 - 09:54
New research by Joseph Reiner and colleagues at Virginia Commonwealth University shows promise for a urine-based test for ovarian cancer. Reiner will present their research at the 68th Biophysical Society Annual Meeting, to be held February 10 - 14, 2024 in Philadelphia, Pennsylvania.

Understanding how natural genetic variation contributes to adaptive responses to low oxygen

Rss Feed - Mon, 02/12/2024 - 09:48
Humans are still evolving, and Tatum Simonson, PhD, founder and co-director of the Center for Physiological Genomics of Low Oxygen at University of California School of Medicine, plans to use evolution to improve healthcare for all.

Androgen receptor signaling found to upregulate gene driving melanoma severity in men

Rss Feed - Mon, 02/12/2024 - 07:34
Method by which androgen-activated androgen receptors (ARs) increase fucosyltransferase 4 (FUT4) expression.

Pregnant women show significant immune system changes linked to gut microbiome

Rss Feed - Mon, 02/12/2024 - 05:53
How gut microbiota and metabolite changes relate to immune function during pregnancy.

Genetics of estrogen production linked to endometrial cancer risk in postmenopausal women

Rss Feed - Sun, 02/11/2024 - 23:40
A study in eBioMedicine identifies genetic factors regulating blood estrone levels in postmenopausal women, linking specific genetic loci to an increased risk of endometrial cancer, highlighting the role of non-ovarian estrogen production in cancer development.

Stress driving substance use in American teens, study finds

Rss Feed - Sun, 02/11/2024 - 23:11
A study in the Morbidity and Mortality Weekly Report reveals stress and experimentation as primary motivators for substance use among American adolescents, with significant implications for developing targeted interventions and educational programs.

Long COVID in children: A closer look reveals lasting impacts

Rss Feed - Sun, 02/11/2024 - 20:33
A comprehensive review in Pediatrics highlights the significant impact of post-acute sequelae of SARS-CoV-2 (PASC) in children, revealing a wide range of long-term symptoms and the need for further research on its prevalence, risk factors, and mechanisms.

Drug repurposing study finds lonafarnib effective against RSV

Rss Feed - Sun, 02/11/2024 - 19:25
A study in Nature Communications identifies lonafarnib from the ReFRAME drug-repurposing library as a potent inhibitor of the RSV fusion protein, showing promise in reducing RSV infection in vitro and in vivo.

Prenatal exposure to phthalates linked to higher risk of preterm birth and low birth weight

Rss Feed - Sun, 02/11/2024 - 19:04
Research in The Lancet Planetary Health links prenatal phthalate exposure to increased risks of preterm birth and low birth weight, underscoring the need for regulatory oversight on chemicals used in consumer products.

Nutrition labels lead to healthier eating in teens, study finds

Rss Feed - Sun, 02/11/2024 - 17:47
Study finds that middle and high school students in Texas who use nutrition labels tend to have healthier eating habits, highlighting the importance of nutrition literacy in promoting better dietary choices among adolescents.

New study finds 4’-fluorouridine effective against avian influenza in vitro and in vivo

Rss Feed - Sun, 02/11/2024 - 17:35
A PLOS Pathogens study reveals 4’-fluorouridine effectively combats avian influenza in vitro and in animal models, showing promise as a treatment that overcomes resistance and reduces disease severity without significant adverse effects.

Unlocking Alzheimer's secrets: Study pinpoints APOE4's harmful effect on lipids

Rss Feed - Fri, 02/09/2024 - 23:32
UNC School of Medicine researcher Sarah Cohen, PhD, and Ian Windham, a former PhD student from the Cohen lab, have made a new discovery about apolipoprotein E (APOE) – the biggest genetic risk factor for late-onset Alzheimer's disease.

Blood biomarkers in TGF-β pathway identify hidden liver cancer risk

Rss Feed - Fri, 02/09/2024 - 23:14
A new research paper was published in Genes & Cancer on February 5, 2023, entitled, "Mechanistically based blood proteomic markers in the TGF-β pathway stratify risk of hepatocellular cancer in patients with cirrhosis."

Blocking artery plus surgery offers hope for reducing reoperations in brain hematoma patients

Rss Feed - Fri, 02/09/2024 - 23:09
Injection of a substance to block an artery feeding the dura (protective sack around the brain) along with surgery to remove pooled blood reduced the risk that patients will require repeat surgery compared to surgical drainage alone, according to preliminary late-breaking science presented today at the American Stroke Association's International Stroke Conference 2024.

Robotic and navigation technology in hip surgery don't raise infection risk, study finds

Rss Feed - Fri, 02/09/2024 - 22:58
For patients undergoing total hip arthroplasty (THA), the use of robotic-assisted surgery and surgical navigation techniques is not associated with an increased risk of periprosthetic joint infection (PJI), suggests a study in The Journal of Bone & Joint Surgery. The journal is published in the Lippincott portfolio by Wolters Kluwer.

Representation matters to Black patients seeking prostate cancer information online, study shows

Rss Feed - Fri, 02/09/2024 - 22:48
For Black men with prostate cancer, racial representation is a key factor affecting trust in websites offering information on prostate cancer, reports a study in the March issue of The Journal of Urology, an Official Journal of the American Urological Association (AUA).

Study shows long COVID's hidden effect on women's sex lives

Rss Feed - Fri, 02/09/2024 - 22:42
From work to school to socializing, COVID-19 has impacted just about every part of our lives-;and now Boston University research has shown that also includes what happens in the bedroom.

New study shows dramatic health benefits of quitting smoking

Rss Feed - Fri, 02/09/2024 - 22:41
People who quit smoking see major gains in life expectancy after just a few years, according to a new study by University of Toronto researchers at Unity Health Toronto.

IPIAD augments standard therapy for pancreatic ductal adenocarcinoma

Rss Feed - Fri, 02/09/2024 - 22:31
A new research perspective was published in Oncoscience (Volume 11) on February 7, 2024, entitled, "IPIAD- an augmentation regimen added to standard treatment of pancreatic ductal adenocarcinoma using already-marketed repurposed drugs irbesartan, pyrimethamine, itraconazole, azithromycin, and dapsone."

Immune system in the blood of Alzheimer's patients found to be epigenetically altered

Rss Feed - Fri, 02/09/2024 - 22:19
​A new Northwestern Medicine study has found the immune system in the blood of Alzheimer's patients is epigenetically altered.

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