Antiphospholipid Syndrome Associated with Systemic Lupus Erythematosus: A Case Report

CASE REPORT
Ina Toska, Ervin Rapushi, Rexhep Shkurti, Anila Mitre

 
For citation: Toska I, Rapushi E, Shkurti R, Mitre A. Antiphospholipid Syndrome Associated with Systemic Lupus Erythematosus: A Case Report. International Journal of Biomedicine. 2025;15(3):598-600. doi:10.21103/Article15(3)_CR3
 
Originally published September 5, 2025

Abstract: 

Antiphospholipid syndrome (APS) is an autoimmune disorder characterized by venous or arterial thrombosis and/or pregnancy outcomes in the presence of persistent antiphospholipid antibodies like lupus anticoagulant (LAC), anti-cardiolipin (aCL), and anti-β2glucoprotein. Antiphospholipid syndrome may occur as a primary disorder or in association with other autoimmune diseases, especially with systemic lupus erythematosus (SLE). This case reports a 28-year-old woman diagnosed with SLE and APS after her first thrombotic event, a deep vein thrombosis (DVT) in the right leg. All SLE patients must be screened for antiphospholipid antibodies, even when thrombotic events have not occurred, to determine the antiphospholipid antibody profile, which is important for future thrombotic risk events. 

Keywords: 
antiphospholipid syndrome • antiphospholipid antibodies • systemic lupus erythematosus
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Received July 15, 2025.
Accepted August 22, 2025.
©2025 International Medical Research and Development Corporation.