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UCLA study reveals key signs for genetic testing in neurodevelopment disorders
In a new study, UCLA Health researchers have found that motor delay and low muscle tone were common signs of an underlying genetic diagnosis in children with neurodevelopment disorders.
Understanding the surprising link between HDL cholesterol quality and Alzheimer's risk
Higher levels of HDL-C-;known as the "good cholesterol"-;have been shown to correlate with heightened risk for Alzheimer's disease.
Unique protein complex found to influence brain function and anxiety
Scientists at Université de Montréal and its affiliated Montreal Clinical Research Institute (IRCM) have uncovered unique roles for a protein complex in the structural organization and function of brain cell connectivity, as well as in specific cognitive behaviors.
Researchers uncover mechanism of protein GBP1 in immune defense
The protein GBP1 is a vital component of our body's natural defence against pathogens. This substance fights against bacteria and parasites by enveloping them in a protein coat, but how the substance manages to do this has remained unknown until now.
University of Michigan receives grant to study pain management in opioid use disorder
The University of Michigan will use a new $3.6 million federal grant to study how pain and opioids after surgery impact people with opioid use disorder, how guidelines might be adjusted to address post-surgical pain and how to prevent opioid-related harms.
Early signs of inflammatory bowel disease detected in newborns
Across the Western world, the prevalence of these chronic and serious conditions, which have no cure, is rising. In Denmark alone, 50,000 people suffer from either Crohn's disease or ulcerative colitis, which represents a doubling in cases over the past 20 years.
Breast cancer patients find hope and connection through YouTube
A study by the University of the Basque Country (UPV/EHU) has identified the most relevant YouTube videos on this disease and the concerns of the people who post comments.
Emphasizing workforce diversity in the One Health approach
A new article highlights a critical issue in the One Health approach-;an emerging global framework for tackling complex health challenges at the intersection of human, animal, and environmental health.
Multidisciplinary approach improves quality of life in functional movement disorders
The research team of the Neurology Department Movement Disorders Unit at the Virgen del Rocío University Hospital and the Movement Disorders group of the Institute of Biomedicine of Seville - IBiS, in collaboration with researchers from the Mental Health Clinical Management Unit and the Translational Psychiatry group coordinated by Benedicto Crespo Facorro (HUVR-IBiS/CIBERSAM), has published a randomized clinical trial demonstrating for the first time that a multidisciplinary approach integrating specific physiotherapy and cognitive-behavioral therapy is effective in improving the symptoms and physical aspects of the quality of life of patients with functional movement disorders.
Comprehensive review finds AI's influence on hospital efficiency lacks clarity
The use of artificial intelligence (AI) in hospitals and patient care is steadily increasing. Especially in specialist areas with a high proportion of imaging, such as radiology, AI has long been part of everyday clinical practice.
Study unveils new molecular switch protecting cells from death
Researchers at LMU University Hospital have discovered a new molecular switch that protects against cell death.
Umeå University discovers critical mechanisms in stem cell differentiation
A study led by Umeå University, Sweden, presents new discoveries about how stem cells develop and transition into specialised cells. The discovery can provide increased understanding of how cells divide and grow uncontrollably so that cancer develops.
Innovative nanodiscs offer less invasive method for deep brain stimulation
Novel magnetic nanodiscs could provide a much less invasive way of stimulating parts of the brain, paving the way for stimulation therapies without implants or genetic modification, MIT researchers report.
Protein discovery offers insights into bone health and potential treatments for osteoporosis
Scientists have identified a protein that blocks the activity of bone-forming cells (osteoblasts) by stopping them from maturing during the journey to sites of bone formation, a new study has found.
Researchers develop innovative mouse model for studying cancer immunotherapy
Immunity plays a central role in the fight against cancer. Many of the current immunotherapies aim at helping the patient's immune system to better recognize cancer cells - by using engineered antibodies - or by simply providing it with new cells, pre-equipped to search and destroy cancer.
Innovative tissue expansion technique transforms conventional microscopy capabilities
A classical way to image nanoscale structures in cells is with high-powered, expensive super-resolution microscopes. As an alternative, MIT researchers have developed a way to expand tissue before imaging it -; a technique that allows them to achieve nanoscale resolution with a conventional light microscope.
Harnessing neural networks to forecast treatment outcomes in small cell lung cancer
As immunotherapy makes breakthrough progress in the treatment of small cell lung cancer (SCLC), predicting treatment outcomes has become a focal point in clinical practice. Immunotherapy combined with chemotherapy has been approved as first-line therapy for small cell lung cancer due to its survival benefit in randomized controlled trials.
New study reveals unique metabolic function of lung-resident NK immune cells
Trinity College Dublin researchers, based at St James's Hospital have provided important insights into the behavior and metabolic function of a previously largely unknown, but crucial 'natural killer' (NK) immune cell resident in the lungs.
Newly identified 'headspin hole' affects breakdancers’ scalp health
Breakdancers may be at risk of developing a condition caused by repeatedly doing a cardinal move of their practice and performance-;the headspin-;warn doctors in the journal BMJ Case Reports.
Gene editing enhances immunotherapy success by preventing T-cell exhaustion
Immunotherapy, using a patient's own immune system to treat disease, has shown promise in some patients with cancer but has not worked in most.