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Why vaginal microbiota transplants aren’t working yet
Vaginal microbiota transplantation without antibiotics fails to restore microbiome balance, yet engraftment suggests avenues for enhancing treatment efficacy.
New genetic ‘roadmap’ advances precision therapy for intrahepatic cholangiocarcinoma
The 1,341-gene signature for intrahepatic cholangiocarcinoma offers a framework for precise diagnosis and tailored therapies, addressing tumor heterogeneity.
Vaping beats traditional tools for quitting smoking
The review indicates nicotine e-cigarettes could surpass traditional quit aids in effectiveness, but lingering safety uncertainties warrant further research.
Dropped surgical implants are contaminated instantly and alcohol does not fix it
A study evaluates disinfectants for decontaminating dropped implants in surgery, highlighting risks and the efficacy of CHG and PI in reducing bacterial load.
Mapping the physical forces that propel proteins forward
Scientists at Oregon Health & Science University have uncovered a previously unknown system of internal "trade winds" that help cells rapidly move essential proteins to the front of the cell, reshaping how researchers understand cell migration, cancer spread and wound healing.
DNASE1L2 identified as a dynamic biomarker for TB progression
Tuberculosis (TB) remains one of the world's most serious public health threats, with approximately one-quarter of the global population infected with Mycobacterium tuberculosis. While most infections remain latent (LTBI), individuals with LTBI are at risk of progressing to active TB and potentially becoming new sources of transmission.
Uncovering the hidden retinal risks of modern dentistry
Dentists are exposed to intense lighting for long hours, but its long-term impact on eye health is often overlooked. This study evaluates whether chronic exposure to dental lighting, especially blue and white LEDs, can damage the retina and disrupt its normal function. By combining human data with advanced imaging and animal models, the research uncovers hidden occupational risks and highlights the need for safer lighting practices to help protect dentists' vision.
Using machine learning to scan post-cancer health risks
Artificial intelligence (AI) could help physicians determine if survivors of childhood cancer need extra support - and the more information included in AI prompting, the better its performance. This finding, published today in Communications Medicine by scientists from St. Jude Children's Research Hospital, may guide future integration of AI into clinical workflows.
How video gaming may shape sleep, diet, and activity across the lifespan
This narrative review found that video gaming can have both benefits and risks for health across the lifespan. It may provide short-term stress relief and social connection, but frequent or prolonged gaming is also associated with sedentary behaviour, poorer sleep, disrupted eating patterns, and lower diet quality, with effects shaped by age, sex, timing, content, and motivation.
Children’s screen use surged significantly during and after pandemic
First systematic review to track long-term trends across pre- and post-pandemic periods finds dramatic rise in screen use among children and adolescents.
How gut imbalance may drive obesity, diabetes, and heart disease
A new review argues that gut dysbiosis is closely linked to metabolic dysfunction through intertwined effects on inflammation, oxidative stress, gut barrier integrity, microbial metabolites, and epigenetic regulation. It also highlights microbiome-targeted strategies such as high-fiber diets, probiotics, prebiotics, postbiotics, exercise, and fecal microbiota transplantation as promising ways to support metabolic health.
Study proposes genetic basis for autism’s strong sex bias
Autism has a significant and enduring sex bias, with roughly four boys diagnosed for every girl. For many years, experts have believed this disparity arises primarily from diagnostic inequities because much of autism research - and the screening tools that grew out of it - has historically focused on boys, effectively setting a male standard for what autism "looks like."
How do diet, smoking, alcohol, and stress reshape the female microbiome?
This review examines how modifiable lifestyle and environmental factors shape the female vaginal, gut, oral, and skin microbiomes, with diet, alcohol, smoking, obesity, stress, hygiene, physical activity, and sexual behaviours all linked to site-specific microbial shifts. It argues that understanding these patterns could help guide future female-focused prevention and intervention strategies.
Sleep brain activity offers clues to infant neurological development
Electrical signals from the brain could help identify potential issues in the organ's development, a new study reports.
Modern lifestyle amplifies genetic risk for type 2 diabetes
Some people have a greater genetic risk than others of developing type 2 diabetes. Now, more of these at-risk people are actually developing diabetes than previously.
Retinal organoid study identifies pathways and compounds to protect cone cells
Scientists led by Botond Roska at the Institute of Molecular and Clinical Ophthalmology Basel (IOB) and collaborators have identified genetic pathways and compounds capable of protecting cone photoreceptors from the degeneration that underlies conditions like age-related macular degeneration.
Collaboration advances EMA601 as potential first-in-class stroke therapy
Boehringer Ingelheim and the Lower Franconian biotech company EMFRET Analytics have signed a cooperation and license agreement for the preclinical development program of the GPVI‑blocking antibody EMA601.
Swimming in treated pools safe for children with tympanostomy tubes
A new study published in Otolaryngology−Head and Neck Surgery, the peer-reviewed journal of the American Academy of Otolaryngology−Head and Neck Surgery Foundation (AAO-HNSF), finds that children with tympanostomy tubes who swim in treated pools are not at increased risk of ear drainage, while those exposed to untreated or natural bodies of water face significantly higher odds of developing recurrent otorrhea.
Alcohol impacts gene expression differently across brain regions
Erica Periandri and Gabor Egervari, from Washington University in St. Louis, led a study to explore how alcohol exposure in male mice influences gene expression and mechanisms that regulate gene function-or epigenetics.
Artemin identified as marker and target in feline osteoarthritis
By comparing osteoarthritis pain pathways known to be active in dogs and humans to those in cats with degenerative joint disease (DJD), researchers found that elevation of a particular molecule, artemin, could serve as a marker of disease (and possibly pain) as well as a potential therapeutic target.




