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PET microplastics remain in lungs and worsen respiratory tract inflammation
Microplastics (MP) are the subject of intensive medical research, but little is yet known about their effects on the immune system.
Study reveals right ventricle better tolerates oxygen loss during cardiac arrest
A study led by scientists at the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC) provides new insights into ventricular fibrillation (VF), the most dangerous type of cardiac arrhythmia.
Urine-based autism screening using gut microbial metabolites
Elevated gut microbe metabolites may distinguish children with autism, paving the way for a non-invasive urine test and a new ASD subtype linked to microbiome.
Could guava juice help prevent anemia?
Guava juice intake is linked to increased hemoglobin levels in females, highlighting its role as a dietary complement to traditional iron supplementation.
Half of clinical trial professionals cite trust and regulatory gaps as barrier to AI adoption, Pistoia Alliance poll finds
The Pistoia Alliance, a global, not-for-profit alliance that advocates for greater collaboration in life sciences R&D, has released new poll data showing trust and regulatory uncertainty are the biggest barriers to AI adoption in clinical trials, cited by half of respondents (50 %).
Sino Biological’s Cell-Free Protein Synthesis supports Tencent AI for Life Sciences Lab’s protein design study published in Nature Communications
Sino Biological, Inc. has announced that its gene synthesis and cell-free protein expression workflow was used in a recent study by Tencent AI for Life Sciences Lab published in Nature Communications, enabling rapid validation of AI-designed proteins with improved activity, stability, and multifunctionality
Scientists uncover shared gene signatures that reveal how mammals age
Researchers mapped more than 11,000 transcriptomes across mice, rats, macaques, and humans, revealing conserved molecular signatures of aging and mortality across tissues, species, and cell types. The study developed interpretable transcriptomic clocks that track age, mortality-related molecular change, chronic disease signals and responses to lifespan-altering interventions.
Gut microbes may reveal who is at risk of type 2 diabetes years before diagnosis
A large Swedish prospective cohort study found that specific gut microbial species and metabolic pathways measured years before diagnosis were associated with future type 2 diabetes risk. The findings suggest that gut microbiome composition and functional potential may help explain T2D development, but replication is needed before clinical use.
UCLA researchers identify brain circuit controlling memory organization
When a person has a new experience, their brain faces a subtle but critical decision: should this experience be categorized with other stored memories, or should it be filed away as its own new memory? Getting it right allows the brain to help people navigate the world.
Gut changes linger years after polyp removal and may signal colorectal cancer risk
Researchers found that women who had undergone colorectal adenoma resection still showed gut microbiome and fecal metabolome alterations an average of about 12 years later. These persistent changes partly resembled colorectal cancer-associated patterns, suggesting that the host-microbiome axis may remain altered along the adenoma-cancer continuum.
Mental health challenges linked to hidden online harms among youth
A new study from researchers at the Child Mind Institute finds that negative online experiences are common among children and adolescents with mental health and neurodevelopmental conditions, and that most incidents are not reported through platform reporting tools.
AI maps how brain fluids move to clear waste
MR-AIV uses physics-informed AI and DCE-MRI scans to infer 3D brain-wide fluid movement in mice without direct flow measurements. The method distinguished slow diffusion-dominated transport from faster advective flow and estimated pressure and permeability patterns linked to brain waste clearance.
Obesity alters tumor environment promoting invasive breast cancer growth
Obesity may change how early-stage breast cancer becomes invasive, according to a study by University of Oklahoma researchers published in The American Journal of Pathology.
Smokers undergoing lung cancer surgery face higher complication risks
Researchers at the University of Cincinnati College of Medicine have found that patients who continue to smoke ahead of lung cancer surgery have a higher risk of pulmonary complications, but their short-term mortality rate is similar to patients who were able to stop smoking before surgery.
Low protein intake linked to declining physical function with age
Researchers have found that consuming lower amounts of protein-rich foods may negatively affect physical functioning as people grow older, underscoring the vital function protein plays in preserving mobility and muscle strength in adulthood.
Menstrual pain relief purchases reveal stark income-related healthcare disparities
More than a quarter of women buying menstrual products also purchase pain relief at the same time-and those in lower-income areas are significantly less likely to do so-according to a new study published this week in the open-access journal PLOS Digital Health by Dr. Victoria Sivill of the University of Bristol, UK, and colleagues, which used supermarket loyalty card data to map menstrual pain disparities across England.
LSU study examines how restrained sitting limits early childhood movement
Researchers at LSU's Pennington Biomedical Research Center, in collaboration with investigators from 32 countries participating in the SUNRISE International Study, have published new findings examining how restrained sitting contributes to daily movement patterns in early childhood.
Mental health diagnostic interviews are less consistent than thought
Diagnostic interviews are widely used by mental health professionals to identify conditions such as anxiety, bipolar disorder and depression in adults, but new research led by McMaster University shows that the long considered "gold standard" may not be as consistent as previously thought.
Mount Sinai study links long COVID symptoms to autoimmunity
A Mount Sinai-led research team has demonstrated that autoimmunity, where the body's immune system attacks its own tissues, is responsible for the often-debilitating and confounding symptoms of long COVID in a subset of people.
Study uncovers a biological link between chronic oral inflammation and female fertility
Chronic oral inflammation may impair female fertility by triggering a systemic immune response that affects the ovaries.




