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Study reveals stepwise formation of cerebellar projections in the developing brain
A team of researchers at the Institute for Neurosciences (IN), a joint center of the Spanish National Research Council (CSIC) and Miguel Hernández University of Elche (UMH), has reconstructed for the first time how the cerebellum establishes its connections with the rest of the brain during the earliest stages of life.
Review highlights emerging role of tumor MHC-II in shaping cancer immunotherapy outcomes
Cancer immunotherapy has transformed cancer treatment, yet many patients experience limited or short-lived responses due to immune evasion, tumor heterogeneity, and immune-related adverse events.
Study reveals how Ebola and Marburg viruses damage the human gut
Ebola (EBOV) and Marburg virus (MARV) are highly lethal viruses that cause severe disease in infected patients by extensively damaging the body.
Researchers identify enzyme linked to myelin damage and neurodegenerative conditions
Researchers at Oregon Health & Science University have identified a type of enzyme with a complicated name - cell migration inducing and hyaluronan-binding protein, or CEMIP - is associated with disorders ranging from multiple sclerosis to stroke to neurodegenerative conditions like Alzheimer's disease.
White bread vs wholegrain: which one is actually better for your health?
This review dispels common myths about white and wholegrain bread by examining their composition processing and health effects. It concludes that while wholegrain breads offer added benefits white bread remains a safe affordable and nutritionally meaningful staple when fortified.
Researchers discover the enzyme responsible for chromothripsis in cancer
University of California San Diego researchers have discovered the enzyme responsible for chromothripsis, a process in which a single chromosome is shattered into pieces and rearranged in a scrambled order, allowing cancer cells to rapidly evolve and become resistant to treatment.
AI-based tool may help personalize the treatment of patients with reduced coronary blood flow
Reduced coronary blood flow, measured with an artificial intelligence-based imaging tool, predicted future cardiovascular events in patients with suspected stable coronary artery disease.
Teenagers with body image issues may develop eating disorders and depression later
Teenagers who are unhappy with their bodies are more likely to develop symptoms of eating disorders and depression in early adulthood, according to a new study led by UCL researchers.
Blocking collagen signaling improves the delivery of macromolecular drugs in pancreatic cancer
Pancreatic cancer is one of the deadliest malignancies, with survival rates remaining dismally low despite major advances in oncology.
Preoperative radiation may enhance treatment response in patients with HR-positive, HER2-negative breast cancer
Preoperative radiation improved T-cell infiltration (TCI) in patients with hormone receptor (HR)-positive, HER2-negative breast cancer when administered in combination with pembrolizumab (Keytruda) and chemotherapy and led to improved treatment responses prior to surgery, according to the results of the phase II P-RAD clinical trial presented at the San Antonio Breast Cancer Symposium (SABCS), held December 9-12, 2025.
Skipping sentinel lymph node biopsy may be safe for some early-stage breast cancer patients
Skipping sentinel lymph node biopsy (SLNB) in patients with clinically node-negative, hormonal receptor (HR)-positive, HER2-negative early-stage breast cancer did not compromise regional control or survival after a median five years of follow-up, according to results from the BOOG 2013-08 phase III clinical trial, presented at the San Antonio Breast Cancer Symposium (SABCS), held December 9-12, 2025.
Frequency and quantity of alcohol consumption influence cancer risk
As Americans gear up for the holiday season, new research offers a timely reminder to reflect on the long-term health effects of raising a celebratory glass – or two.
Researchers identify a distinct immuno-inflammatory biomarker across major psychiatric disorders
Individuals with psychiatric disorders exhibiting seemingly similar symptoms often respond very differently to the same treatment, suggesting that distinct biological processes are at work beneath the surface of similar clinical presentations.
Study finds sharp rise in prescriptions for stimulant medications used to treat ADHD
A new Ontario-based study has found a significant rise in prescriptions for stimulant medications used to treat attention-deficit/hyperactivity disorder (ADHD), particularly among adults and females.
Missing piece of myelin results in slower, less consistent signal transmission to the brain
Our nerve cells are surrounded by a protective layer (myelin). This protective layer allows signals to pass between cells incredibly quickly.
Interventions to treat valvular heart disease in cancer patients significantly improve survival
Valvular heart disease, identified through cardiovascular imaging, is common in cancer patients. Interventions to treat valvular heart disease significantly improved survival.
Shared genetic roots of 14 psychiatric disorders revealed
Researchers from the Psychiatric Genomics Consortium (PGC) report that most genetic influences on mental illness are shared across diagnostic categories, revealing a more interconnected biological landscape than traditional classifications suggest.
Psoriasis caused by changes in the fat metabolism of skin cells
A research team led by Erwin F. Wagner from the Medical University of Vienna has discovered a previously unknown molecular mechanism that contributes to the development of psoriasis - and at the same time represents a potential biomarker for a new treatment concept.
RSV can have profound, long-lasting effects in hospitalized adults
Respiratory syncytial virus, commonly known as RSV, is often associated with cold-like symptoms in young children.
What happens to your body during an ultramarathon? New study reveals key metabolic changes
This study tracked ultramarathon runners across 100 km, 160.9 km, and 230 km events to examine real-world metabolic, hormonal, and muscle stress responses. Severe energy deficits, muscle damage, and heterogeneous hormonal shifts were observed, with the greatest strain seen in the 230 km distance.




