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Study isolates mania-specific genetic architecture in bipolar disorder
Researchers at King's College London and the University of Florence have, for the first time, identified the specific genetic blueprint of mania, the defining feature of bipolar disorder.
Sleeping without pillows may help reduce nighttime eye pressure in glaucoma
Sleeping without pillows may help lower high internal eye pressure, build-up of which causes optic nerve damage and glaucoma-the leading cause of irreversible blindness worldwide–in people with the condition, suggests preliminary research, published online in the British Journal of Ophthalmology.
First topical CRISPR gene therapy corrects disease-causing mutations in human skin
Gene-editing tools like CRISPR have unlocked new treatments for previously uncurable diseases. Now, researchers at the University of British Columbia are extending those possibilities to the skin for the first time.
Depression and anxiety together raise long COVID risk in older women
Older women who have a history of both depression and anxiety had a 78% higher risk of developing long COVID after a SARS-CoV-2 infection, report University of California San Diego researchers in the Jan. 27, 2026 online edition of the journal Menopause.
Purdue researchers discover new therapeutic target for triple-negative breast cancer
A Purdue University team led by Kyle Cottrell has discovered a new therapeutic target for triple-negative breast cancer.
Antibody-producing plasma cells shape effectiveness of PD-1 immunotherapy
Scientists at the Icahn School of Medicine at Mount Sinai have identified an important immune response that helps explain why some cancer patients benefit from immunotherapy while others do not.
Overactive protein cleanup disrupts nuclear pores in neurodegenerative disease
When it comes to neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) and certain forms of dementia, researchers have known that protein quality control and damage to the nuclear pore are key players.
Immune system dysfunction may fuel progressive heart failure after heart attacks
When the heart's muscle is weakened or injured due to a heart attack, it can make it hard for the heart to pump enough blood to meet the body's needs.
MRI measures of glymphatic activity may improve noninvasive intracranial hypertension diagnosis
A new study led by investigators from Mass General Brigham shows that a brain waste- "clean-up" system is influenced by intracranial pressure.
Study reveals heart, brain, neuroimmune connections driving damage after heart attacks
Arteries become clogged. Blood flow is restricted and oxygen is cut off. The result is a heart attack, the world's leading cause of death.
Richer social environments linked to better cognitive health in aging adults
Research by an interdisciplinary team from McGill University and Université Laval provides new insights into the links between social factors and cognitive health among aging adults.
Brain-specific enzyme drives branching and extension of O-mannose glycans
Gifu University scientists have uncovered how a brain-specific enzyme reshapes protein-linked sugar chains to facilitate the formation of complex glycans essential for normal brain function.
PFOA exposure disrupts hormone signaling and impairs embryo implantation in mice
A new experimental study has found that perfluorooctanoic acid (PFOA), a widely used industrial chemical, can interfere with key biological processes required for successful embryo implantation, raising concerns about its potential impact on female fertility.
Gut problems may shape Parkinson’s disease progression through the gut-brain axis
This narrative review examines how gastrointestinal dysfunction, gut dysbiosis, and altered gut-brain axis signaling are closely associated with the onset and progression of Parkinson’s disease. It synthesizes evidence supporting a possible bottom-up disease model while highlighting integrative, gut-targeted strategies as adjuncts to symptom management rather than proven disease-modifying therapies.
How modern lifestyles reprogram the gut microbiome and shape disease risk
Modern lifestyle factors such as circadian disruption, sleep deprivation, stress, and exercise reshape the gut bacteriome and its metabolic outputs.
These microbiome changes are linked to immune, metabolic, and cancer-related pathways, largely through evidence from animal models and observational human studies.
UH psychologist provides guidance to improve mental health of sexual violence victims
A psychologist at the University of Houston is providing guidance to improve the mental health of victims of sexual violence, recognized by major health organizations as a public health crisis with serious implications on victims' physical, mental and reproductive health.
Hospital-based program reduces re-injury, violence among victims
A hospital-based program that supports victims of gun and knife violence can reduce the likelihood that those victims will be reinjured or commit violence themselves, according to a new Boston University study.
Pancreatic and 'skinny fat' linked to brain health risks
The effect of obesity on brain health may depend not only on how much fat is in the body, but also on the areas of the body where fat is stored, according to a study published today in Radiology, the flagship journal of the Radiological Society of North America (RSNA).
Scientists offer new insight into how common parasite T. gondii causes disease
A University of California, Riverside team of scientists has found that Toxoplasma gondii, a common parasite affecting up to one-third of the global population, is far more complex than previously believed.
Brain organoids reveal glioblastoma's secrets and therapy resistance
UCLA scientists have developed advanced miniature 3D tumor organoid models that make it possible to study glioblastoma tumors in a setting that closely mirrors the human brain, shedding light on how the aggressive cancer interacts with surrounding brain cells and the immune system to become more invasive and resistant to therapy.




