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A cross-sectional NHANES study of 8,975 U.S. adults found that higher total dietary sugar intake was associated with higher odds of gallstones, with each 100 g/day increase linked to a 41% rise after full adjustment. The findings suggest sugar intake may be a modifiable gallstone risk factor, but the study relied on self-reported gallstones and cannot establish causation.

Researchers showed that chronic colitis leaves a long-lasting epigenetic memory in colonic stem cells, persisting for more than 100 days after recovery in mice. This memory is marked by durable AP-1-linked chromatin changes and later amplifies tumour outgrowth after oncogenic mutation.

APOE4 drove sex-specific changes in meningeal immunity, lymphatic drainage, brain lipids, neuroinflammation, and cognition in mouse models, with females showing greater inflammatory and cognitive vulnerability. Suppressing innate immunity improved some cognitive outcomes in female E4/E4 mice but worsened them in male E4/E4 mice, underscoring the need for sex-tailored approaches.

Black adults with high blood pressure who received dietitian counseling and home deliveries of groceries aligned with the DASH diet—meaning high in fruits, vegetables, whole grains, low-fat dairy, nuts, seeds, legumes and lean proteins—had an average overall reduction in systolic blood pressure of 7 mm Hg at three months overall and a 5 mm Hg reduction compared with participants who received only basic dietary guidance and a grocery stipend, according to a study presented at the American College of Cardiology's Annual Scientific Session (ACC.26).

The MOMENTUM study found 27 percent of patients with resistant hypertension have hypercortisolism. This is a significant finding, demonstrating that hypercortisolism is more common in these patients than previously understood by researchers and clinicians.

Using a microaxial flow pump prior to and during cardiac stenting procedures for patients with severe heart attacks who don't have cardiogenic shock does not significantly reduce heart damage.

Patients who had low doses of clot-buster drugs delivered directly to the site of a pulmonary embolism (PE) via a catheter using ultrasound to enhance their effect had significantly better outcomes than those who received standard systemic anticoagulants, according to a study presented at the American College of Cardiology's Annual Scientific Session (ACC.26).

The first randomized trial to test whether adding a small, temporary pump to allow the heart to rest and intentionally delaying percutaneous coronary intervention (PCI), also known as coronary angioplasty, for 30 minutes to reduce heart damage compared with standard immediate PCI in patients with heart attacks at risk for a large amount of heart damage found no significant difference between the two groups, the study's primary endpoint. The research was presented at the American College of Cardiology's Annual Scientific Session (ACC.26).

For patients with non-valvular atrial fibrillation (AFib) who had no contraindications to taking oral anticoagulants, the use of a device to close off the left atrial appendage in the heart—a small pouch where blood can pool and form dangerous clots—was comparable to standard medication therapy in reducing the combined rate of all-cause stroke, cardiovascular death and systemic embolism at three years.

Higher left atrial end-systolic dimension (LASD), an increased measurement of the left upper chamber of the heart, and left ventricular mass (LVM), a clinical measurement of the weight of the heart's left ventricular myocardium, are well-established indicators of cardiovascular damage that are associated with a higher risk of cardiovascular disease (CVD) in the short-term (less than 10 years).

Terahertz (THz) radiation is increasingly explored for biomedical applications, however, its non-thermal effects on cellular metabolism and regulatory networks remain insufficiently characterized.

Human immunodeficiency virus (HIV)/hepatitis C virus (HCV) coinfection leads to severe systemic inflammation, increasing non-AIDS morbidity and mortality risk. CD39 ectoenzyme on T-cells, which catalyzes the conversion of pro-inflammatory purines to immunosuppressive adenosine, plays an important role in inflammation control.

Play is critical for kids’ development — but ‘play’ in research is often defined by adult scientists, not the children themselves.

Researchers at the University of Seville's Food Colour and Quality Laboratory have studied the effects of different cooking methods used for tomatoes and carrots (in the oven, microwave or air fryer, amongst others) on the amount of carotenoids that are potentially available for absorption by the body following the digestion of these foods.

In 2023, globally 259,000 people died from meningitis and 2.5 million people were infected with the disease, suggests a study published in The Lancet Neurology.

Postmenopausal women face a high risk of bone fractures. Due to declines in estrogen levels, which can lead to an increased risk of osteoporosis, even a low-impact fall can result in a serious hip, back or wrist injury.

Research from Italy to be presented at this year's European Congress on Obesity (ECO 2026, Istanbul, Turkey, 12-15 May) and published in the journal Nutrients shows that when the gold standard technique of dual-energy X-ray absorptiometry (DXA) is used to measure body fat in the general population, it shows that the traditional WHO body mass index (BMI) classification system misidentifies significant numbers of people as having overweight or obesity.

Discovering how the bird flu virus degrades in the air around livestock and how engineering solutions can effect that degradation quickly and efficiently are core aims of a new University of Michigan Engineering-led project funded by the U.S. Department of Agriculture.

Multiple sclerosis (MS) is a debilitating neurological disorder caused by malfunctioning immune responses that target the brain and spinal cord of the central nervous system (CNS).

The study "Diagnostic Timing and Ovarian Cancer Survival in North Carolina" has been published in the latest issue of JAMA Network Open. Led by a team of UNC-Chapel Hill researchers, this study explored the relationship between survival and how quickly patients are diagnosed with ovarian cancer.