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Paternal mental health risks increase after childbirth, with delayed detection of psychiatric disorders underscoring the need for targeted support for fathers.

Chronic diseases including cancer, diabetes, neurocognitive disorders and infertility are rising globally, with health-harming products such as fossil fuels, tobacco, ultra‑processed foods, toxic chemicals, plastics and alcohol being major contributors, say the authors of a new paper published in New England Journal of Medicine (NEJM). The authors include proposed solutions, including policy safeguards and a stronger research focus on the risks to health connected with corporate activity.

Microtubules, the dynamic filaments that form the cell's internal scaffolding, have long been viewed as mere passive structural supports. But a new study reveals they play a far more active signaling role. The findings, published in Science Advances, demonstrate that microtubules are in fact regulators of enzymatic reactions through reshaping the geometry of the enzyme's substrate proteins attached to them and controlling when key events occur to conduct cell division.

A team of researchers at Baylor College of Medicine, St. Jude Children's Research Hospital, Texas Children's Hospital, and collaborating institutions reveals in the journal Nature a novel mechanism that drives the development of pediatric supratentorial ependymoma (EPN), the third most common pediatric brain tumor. The findings suggest potential new approaches to treat these aggressive and chemo-resistant tumors.

When you reach into a bucket of ice, open your front door on a snowy day, or feel the tingle of menthol toothpaste, a protein in your nerve cells called TRPM8 springs into action, opening like a tiny gate to send a "cold" signal to your brain.

Formate is a key chemical building block widely used across industries. Converting carbon dioxide (CO2) into formate via hydrogenation provides a promising approach to transform a greenhouse gas into a high-value chemical. However, while heterogeneous catalysts based on non-precious metals have been explored for this reaction, their practical application has been limited by low intrinsic reactivity.

Rutgers Health research shows the risk of developing early cardiovascular disease or dying from cardiovascular disease by the age of 28 was 4.6 times higher among people born to mothers who had a placental abruption during their pregnancy.

Human papillomavirus (HPV) is the most common sexually transmitted infection worldwide and can cause various types of cancer. Prophylactic HPV vaccination is highly effective and has been recommended in Switzerland since 2007 for girls and young women aged 11 to 26 – and since 2015 also for boys and young men. Catch-up vaccination is also available for women up to the age of 45.

An international team led by researchers at Baylor College of Medicine, Texas Children's Hospital, McGill University and University of Pittsburgh School of Medicine has discovered what drives the growth of a lethal pediatric brain tumor called Posterior Fossa Type A (PFA) ependymoma.

In a bid to better understand, and potentially treat, a host of conditions that affect early cognition, neurodevelopment and the brain later in life, investigators at Johns Hopkins Medicine and colleagues throughout the world have been mapping the molecular construction of the human brain.

A major new study, led by scientists at University College Dublin and the University of Edinburgh and funded by the St John of God Research Foundation, has found that commonly prescribed attention deficit hyperactivity disorder (ADHD) medication in childhood may lower the long‑term risk of developing serious psychotic disorders, including schizophrenia.

A study of 627 Saudi university students found that higher social media addiction was associated with more anxiety and depression, while family environment fully mediated those links in the statistical model. The findings suggest that supportive family relationships may help buffer the mental health burden associated with problematic social media use, although the cross-sectional design does not establish causation.

Evidence-based parenting programs delivered through community organisations can support family wellbeing and should be considered as part of wider strategies to reduce health inequalities, a landmark UCL study has found.

Hormone patches are as good at controlling locally advanced prostate cancer as the injections typically used to deliver hormone therapy, according to the results of a large clinical trial led by UCL (University College London) researchers.

Patients with breast cancer may be able to avoid lymphedema, which can occur after surgery to remove lymph nodes in the armpit (the axilla), by having radiotherapy instead.

In a new study published in The Lancet Digital Health, scientists at the USC Mark and Mary Stevens Neuroimaging and Informatics Institute (Stevens INI) have discovered that the brains of people who experience severe physical impairment after a stroke may reorganize themselves in unexpected ways, showing signs of "younger" brain structure in undamaged regions as they adapt to injury.

Excessive consumption of dietary sodium (salt) is a significant, independent risk factor for new-onset heart failure, according to a report from Vanderbilt Health.

Researchers at the CU Anschutz Cancer Center have discovered how breast cancer cells that spread to the lungs may take advantage of the body's natural healing response and how a commonly used drug might slow that process.

CDC surveillance shows that the highly divergent SARS-CoV-2 variant BA.3.2 spread to at least 23 countries and was detected in U.S. travelers, patients, airplane wastewater, and wastewater samples across multiple states. The report highlights wastewater and traveler-based genomic surveillance as early warning tools while noting that BA.3.2 has immune-evasion potential but has not rapidly displaced other circulating lineages.

Researchers found that both radiologists and multimodal AI models had only moderate success distinguishing synthetic radiographs from real clinical images, even when told fakes were present. The study warns that increasingly realistic AI-generated X-rays could be misused in medicine, research, insurance, and litigation, strengthening the case for watermarking, clinician training, and dedicated detection tools.