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Updated: 56 min 58 sec ago

Short-term oatmeal diet improves cholesterol and metabolic health markers

Fri, 01/23/2026 - 23:57
A short-term oat-based diet appears to be surprisingly effective at reducing the cholesterol level. This is indicated by a trial by the University of Bonn, which has now been published in the journal Nature Communications.

Evidence of African lineage Zika virus circulation in neotropical primates in Southern Brazil

Fri, 01/23/2026 - 23:25
Announcing a new article publication for Zoonoses journal. Mosquito-borne orthoflaviviruses are maintained in cycles involving mosquito and vertebrate hosts.

MYC cancer gene suppresses immune alarm signals to protect pancreatic tumors

Fri, 01/23/2026 - 23:14
The cancer gene MYC camouflages tumors by suppressing alarm signals that normally activate the immune system.

Bacterial infections in patients with liver cirrhosis show rising prevalence and high mortality

Fri, 01/23/2026 - 21:35
Bacterial infections (BIs) are common and severe complications in patients with liver cirrhosis, but global data are limited. Here, we aimed to evaluate the global prevalence, temporal changes, and associated mortality risk of BIs in liver cirrhosis.

Cigarette compound exposure drives sorafenib resistance in hepatocellular carcinoma

Fri, 01/23/2026 - 21:31
A research team led by Professor Yuan Li at Nanjing Medical University published a research paper entitled "A Cigarette Compound-Induced Tumor Microenvironment Promotes Sorafenib Resistance in Hepatocellular Carcinoma via the 14-3-3η-Modified Tumor-Associated Proteome" in the Chinese Medical Journal.

Engineered mesenchymal and endothelial cell layers effectively mimic native lymph nodes

Fri, 01/23/2026 - 07:49
The rising incidence of cancer worldwide has led to an increasing number of surgeries that involve the removal of lymph nodes. Although these procedures play a major role in cancer staging and preventing the spread of malignancies, they sometimes come with severe long-term consequences.

New study identifies the optimal exercise dose for reducing hepatic steatosis

Fri, 01/23/2026 - 07:37
Hepatic steatosis is a core pathological feature of metabolic dysfunction-associated steatotic liver disease (MASLD). It not only drives disease progression to intrahepatic conditions such as cirrhosis but also elevates the incidence and mortality risk of cardiovascular diseases and extrahepatic malignancies.

Loss of metabolic control mechanisms promotes uncontrolled cancer cell proliferation

Fri, 01/23/2026 - 07:30
Researchers from the University of Seville have participated in research to identify the molecular details of the regulation of an enzyme essential for sugar metabolism and closely linked to cell proliferation and growth: pyruvate kinase.

Genetic study establishes causal link between obesity and cognitive decline

Fri, 01/23/2026 - 07:22
People with obesity and high blood pressure may face a higher risk of dementia, according to a new study published in The Journal of Clinical Endocrinology & Metabolism.

Peptide-based platform marks a major step toward needle-free diabetes care

Fri, 01/23/2026 - 07:16
For more than a century, oral insulin has been considered a "dream" therapy for diabetes, hindered by enzymatic degradation in the digestive tract and the absence of a dedicated intestinal transport mechanism. Consequently, many patients must rely on daily insulin injections, which can significantly reduce their quality of life.

Scientists discover a non-classical platelet mechanism linked to severe infections

Fri, 01/23/2026 - 07:05
Platelets are small, anucleate blood cells that play an essential role in hemostasis. Their primary task is to recognize vascular injury, become activated, and aggregate via their surface receptor integrin αIIbβ3. This leads to the formation of a stable platelet plug that seals the wound and stops bleeding. When this process becomes dysregulated, however, it can result in vessel-occluding clots - so-called thromboses - which may cause myocardial infarction or stroke.

New findings explain how lysosomal defects trigger neuronal energy failure

Fri, 01/23/2026 - 06:54
Together with colleagues from Stanford University, USA, researchers at the Leibniz Institute on Aging - Fritz Lipmann Institute (FLI) have, for the first time, created a comprehensive cell type-specific atlas of lysosomes in the brain, the cell organelles which are responsible for degradation and recycling processes.

Sedentary adulthood increases biological stress levels by middle age

Fri, 01/23/2026 - 06:39
Prolonged insufficient physical activity in adulthood increases the body's stress burden, according to a large longitudinal study based on the Northern Finland Birth Cohort 1966. By contrast, engaging in physical activity in line with recommended guidelines appears to protect the body from harmful stress.

Is fluoridated water safe during pregnancy? Studies say yes

Fri, 01/23/2026 - 04:24
Research analyzing 11.5 million births finds no association between community water fluoridation and reduced birth weight, ensuring prenatal safety.

Ageing slows brain protein clearance and shifts synaptic waste to microglia

Thu, 01/22/2026 - 23:51
Ageing slows neuronal protein degradation in mice, leading to widespread accumulation and aggregation of long-lived proteins, particularly at synapses. As neuronal clearance declines, microglia selectively accumulate synaptic proteins, suggesting a compensatory but potentially strained proteostasis pathway in the ageing brain.

Trojan horse immunotherapy opens tumors to immune system attack

Thu, 01/22/2026 - 22:16
Scientists at the Icahn School of Medicine at Mount Sinai have developed an experimental immunotherapy that takes an unconventional approach to metastatic cancer: instead of going after cancer cells directly, it targets the cells that protect them.

Nearly half of adults now live with heart disease as obesity and diabetes surge

Thu, 01/22/2026 - 22:15
The 2026 American Heart Association Heart Disease and Stroke Statistics report shows that nearly half of adults are living with cardiovascular disease, with cardiometabolic risk factors projected to rise substantially by 2050. Despite progress in smoking reduction and cholesterol control, worsening obesity, diabetes, hypertension, sleep health, and persistent inequities threaten future cardiovascular health.

New copper-based drug shows promise against antibiotic-resistant MRSA

Thu, 01/22/2026 - 22:13
A research team at the University of Arizona College of Medicine – Tucson is developing a drug that works in combination with copper to kill bacteria, including those that cause MRSA, a type of staph infection that is resistant to usual treatments.

Study traces deep origins of syphilis to prehistoric Americas

Thu, 01/22/2026 - 21:59
A newly sequenced genome of the bacterium that causes syphilis, Treponema pallidum, highlights the deep antiquity of treponemal diseases in the Americas.

Study explores how shared cells influence health across generations

Thu, 01/22/2026 - 21:43
During pregnancy, maternal and fetal cells migrate back and forth across the placenta, with fetal cells entering the mother's bloodstream and tissues.

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