Rss Feed

A Danish nationwide study found that people with type 1 and type 2 diabetes have markedly higher rates of sudden cardiac death than the general population, especially at younger ages. At age 30, people with diabetes lose many years of life, with several of those years specifically attributable to sudden cardiac death.

Long-term antidepressant use in Australia increased steadily between 2014 and 2023, with the largest relative rise seen among adolescents and young adults aged 10 to 24 years. Treatment duration also lengthened over time, while apparent dose reduction efforts remained limited, raising concerns about deprescribing practices.

Patients undergoing treatment for lymphoma often experience adverse side effects that can be so severe that they stop or slow treatment.

Study shows that increasing dietary vitamin C intake with kiwifruit raises vitamin C levels in both the dermis and epidermis through active transport from the bloodstream. Higher skin vitamin C levels were associated with increased skin density and epidermal cell proliferation, but not with improved UV protection or measurable increases in new collagen markers.

A large quasi-experimental study in Wales shows that eligibility for shingles vaccination is linked to fewer new mild cognitive impairment diagnoses and lower dementia-related mortality. Benefits appear strongest in women and are observed at multiple stages of the dementia disease course.

Parental permissiveness toward heavy episodic drinking is higher among Greek-affiliated students and their parents during the transition from high school to college. Students who perceive greater parental approval of heavy drinking report more frequent alcohol use, with this relationship differing by Greek affiliation.

Human researchers outperformed large language models across all major stages of systematic review preparation, particularly in study selection, synthesis, and final manuscript drafting. While LLMs demonstrated speed and partial accuracy in early screening and data extraction, they could not independently produce high-quality, guideline-compliant systematic reviews.

This study shows that preoperative gait speed is a strong predictor of patient-reported pain relief, function, and joint awareness after total hip arthroplasty for osteoarthritis. A walking speed of at least 1.0 m/s before surgery independently predicts excellent postoperative outcomes.

Early exposure to fat-related food odors during development alters central sensory processing and metabolic regulation, independently of maternal obesity or nutrient intake. These sensory cues program long-term susceptibility to obesity, impaired thermogenesis, and altered brain responses to dietary fat in adulthood.

Researchers explore the use of smartphones coupled with clinical scores to evaluate motor function and predict dopamine deficiency.

According to a new trial, patients with chronic lymphocytic leukemia (CLL) show comparable outcomes whether they receive a single-agent treatment indefinitely or a combination treatment for a fixed period of time.

In a new trial, patients with B-acute lymphoblastic leukemia (B-ALL) who had no evidence of remaining cancer cells after prior treatment, experienced comparable outcomes whether they received chemotherapy-based conditioning or total body irradiation (TBI), the standard conditioning regimen used before hematopoietic cell transplantation.

Nearly a third of families with children receiving chemotherapy for acute lymphoblastic leukemia (ALL) – the most common pediatric cancer – develop serious financial difficulties during their child's treatment, including losing 25% or more of their household income and struggling to cover the costs of basic living expenses such as housing, food, and utilities.

Within a year of initiation, a multidisciplinary project to improve screening and treatment for iron deficiency in pregnancy resulted in a sixfold rise in screening rates for iron deficiency in pregnant patients, a 20-fold rise in the number of intravenous (IV) iron infusions, and a significant improvement in median hemoglobin levels.

Treatment with intravenous (IV) iron significantly improved survival and increased hemoglobin levels in patients with iron-deficiency anemia who were hospitalized for an acute bacterial infection, according to an analysis of data from more than 85,000 patients.

Compared with white patients, Black patients with acute myeloid leukemia (AML) were on average more than five years younger at diagnosis, more than 30% more likely to die of their disease, and more than 20% more likely to die of any cause, according to an analysis of data conducted over a 34-year period and supported by the National Cancer Institute (NCI) is a component of the U.S. National Institutes of Health.

Taking the sickle cell drug hydroxyurea during or shortly before pregnancy does not appear to cause specific issues in newborns, according to the first prospective study of pregnancies involving hydroxyurea exposure.

The first study assessing the real-world commercial roll-out of gene therapies for sickle cell disease and beta thalassemia offers lessons learned to inform best practices as manufacturers and medical centers prepare to meet growing demand for gene therapies in the coming years.

Patients who underwent hematopoietic cell transplantation for sickle cell disease saw high rates of survival without disease symptoms and low rates of severe side effects or complications years after their procedure, according to a new study.

A new study finds that only one in three patients visiting emergency departments (EDs) for severe pain associated with sickle cell disease received appropriate opioid-based pain-relieving medications within the first hour as recommended by the American Society of Hematology (ASH) and National Heart, Lung, and Blood Institute (NHLBI).