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State bans on prior authorization show limited impact on buprenorphine treatment retention
State laws that ban insurance prior authorization for buprenorphine-a leading medication for opioid use disorder-may not help more patients stay in treatment for the recommended minimum of 180 days, Weill Cornell Medicine researchers report.
Research reveals nuclear metabolic fingerprint in human cells
More than two hundred metabolic enzymes, many of which are normally tasked with producing energy in the mitochondria, are also found sitting directly on top of human DNA, according to a study published today in Nature Communications.
Scientists identify ANKIB1 as key regulator of innate immune signaling
Innate immune sensors – known as pattern recognition receptors (PRRs) – detect specific molecular components of bacterial or viral intruders.
DNA nanomachine strategy reverses chemoresistance in small cell lung cancer
Professor Chao Zhang's team at Zhujiang Hospital, Southern Medical University, has developed a novel DNA nanomachine-based drug delivery and release strategy aimed at overcoming chemoresistance in small cell lung cancer (SCLC).
TREM2 helps macrophages survive and repair radiation damaged skin
Recently, teams led by Prof. Yiming Zhang from Xinqiao Hospital, Army Medical University,Prof. Fazhi Qi from Zhongshan Hospital, Fudan University, and Prof. Junli Zhou from the Tenth Affiliated Hospital of Southern Medical University (Dongguan People's Hospital), focused on the regulatory mechanisms of macrophage function in radiation-induced skin injury and systematically elucidated the critical role of TREM2 in maintaining macrophage survival and promoting skin repair under radiation stress.
Learning strengthens coordination among sensory neurons in the brain
When you get better at a skill-recognizing a familiar face in a crowd, spotting a typo at a glance, or anticipating the next move in a game-sensory neurons in your brain become more coordinated, sharing information rather than acting more independently.
Studies highlight benefits of osseointegration for patients with limb amputations
Three new studies from Hospital for Special Surgery (HSS) highlight the use and advantages of osseointegration (OI) for individuals with an amputation, in some instances challenging prevailing beliefs about which patients would benefit.
Scientists identify common molecular program across multiple brain tumor types
Research uncovering the origin of pineoblastoma, a rare pediatric brain tumor, has also revealed a dependency across multiple brain tumor types that share a similar molecular program.
Single dose of CAR-astrocyte therapy halves amyloid levels in mice brains
The new generation of Alzheimer's disease drugs - the first proven to change the course of the disease - typically extend independent living for patients by 10 months.
Researchers develop non-hormonal contraceptives to reduce side effects for couples
In the 1970s, the contraceptive pill was the most frequently used method of contraception in Western countries; in Germany, for example, one in three women used "the pill."
New compound shows promise in protecting the liver from damage after small bowel surgery
When parts of the small intestine are diseased or die, the treatment can involve surgically removing the affected tissue.
Adults' exposure to diverse microbes may worsen allergic conditions
The "hygiene hypothesis" suggests exposure to diverse types of microbes may protect against developing diseases caused by allergens, but a new Cornell University study in mice reveals that adults' exposure to diverse microbes and allergens may in fact worsen certain allergic conditions.
New study shows the brain reactivates memories without reaching conscious thought
Researchers have used brain imaging to show how memories can be reactivated in the brain without them reaching conscious awareness, showing that these memories persist even when we think they have been forgotten.
Review identifies sucrose as an effective pain reliever for hospitalized infants
Mariana Bueno, an Assistant Professor at the Lawrence Bloomberg Faculty of Nursing, is the lead author of a recently published Cochrane review investigating the administration of sucrose as a form of pain management for hospitalized infants who undergo venepuncture.
Seniors defy stereotypes of decline through positive mindsets
Aging in later life is often portrayed as a steady slide toward physical and cognitive decline. But a new study by scientists at Yale University suggests an alternate narrative - that older individuals can and do improve over time and their mindset toward aging plays a major part in their success.
Weekend lie-ins may boost insulin sensitivity, but too much may backfire
This study explores the relationship between sleep patterns and insulin sensitivity, emphasizing the impact of weekday sleep and weekend catch-up on metabolism.
Higher pollen levels linked to lower exam scores
New research links pollen exposure to lower exam scores in Finnish students, highlighting its potential impact on academic performance and future opportunities.
COVID-19 lockdown timing tied to changes in executive function
The COVID-19 pandemic affected executive function in young children, with preschoolers showing different cognitive growth patterns linked to maternal education.
MSK uncovers how interacting mutations shield breast cancer
Researchers at Memorial Sloan Kettering Cancer Center (MSK) have made an important discovery about how genetic mutations in breast cancer patients can interact and drive resistance to certain drugs called CDK4/6 inhibitors. This finding, published in Nature, suggests a new strategy for predicting and preventing resistance to specific therapies based on the tumor's genetic profile.
How the brain’s "parental machinery" fuels social support in mice
Humans and animals share a remarkable capacity to sense when others are in distress and respond with comforting behavior. But the motivation for doing so, and why it sometimes breaks down, has been poorly understood.




