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Commonly prescribed cardiovascular medications—such as statins, diuretics, and blood pressure drugs—appear to have little or no negative impact on survival among people living with multiple myeloma, according to new international research.

Announcing a new article publication for BIO Integration journal. Alzheimer's disease (AD) is a neurodegenerative disorder and the leading cause of dementia worldwide. Microglia, as central nervous system (CNS) resident macrophages, are key to AD pathology. Indeed, microglia aggregation around amyloid-β (Aβ) deposits is an AD hallmark.

Research from the University of East Anglia (UEA) may finally explain why we still reach for the biscuit tin, even when we're full.

Researchers developed and validated ElasticNet machine learning models that predict 12-month MMSE and BADL outcomes in Alzheimer’s disease and mild cognitive impairment using routinely collected clinical data. The cognitive model demonstrated external validation in ADNI, showing that individualized progression forecasting is feasible without biomarkers or neuroimaging.

A nationwide ecological study of US counties from 2000 to 2018 found that greater proximity to operational nuclear power plants was associated with higher cancer mortality rates, particularly among adults aged 65–74 years. The analysis used inverse-distance weighting within 200 km and adjusted for demographic, socioeconomic, environmental, and healthcare factors, but did not measure individual radiation exposure.

This review examines how zinc regulates inflammatory and redox signaling pathways involved in myocarditis and pericarditis, highlighting mechanisms such as NF-κB inhibition and the redox zinc switch. The authors conclude that maintaining optimal zinc status may support cardiovascular resilience, while emphasizing that clinical translation requires further targeted trials.

Researchers analyzed over 272,000 UK Biobank participants and used Mendelian randomization to investigate whether circulating phenylalanine and tyrosine influence lifespan. Genetically predicted higher tyrosine levels were linked to shorter lifespan, particularly in men, while phenylalanine showed no independent effect after adjustment.

On the occasion of Rare Disease Day, the Biofisika Institute (CSIC, EHU) presents the progress of a project aimed at understanding the molecular origin of CTNNB1 neurodevelopmental syndrome, a rare disease caused by mutations in the beta-catenin protein.

To further the quantitative understanding of cellular decision making, Dr. Gregory Reeves and his team in the chemical engineering department have worked to interpret how a transcription factor dictates the alteration of gene expression in cells.

Today, more than half of older Americans receive their Medicare coverage through private Medicare Advantage plans. In 2020, that program made a sweeping policy shift, allowing those plans to offer supplemental benefits beyond traditional medical care, including groceries, meal deliveries, utilities, transportation, pest control, and air filters.

Chronic pain is one of the most common health conditions worldwide. Back pain is the most frequently reported type, followed closely by head and face pain linked to the jaw joint, in the form of temporomandibular joint (TMJ) disorder.

Rice feeds more than half of the world's population, yet we still only partly understand the nutrients it contains.

Nitrous oxide used for sedating patients during dental appointments has a significant environmental impact, with wide variation in use and wastage across the UK, according to a new study by UCL (University College London) researchers.

New research by engineers at the University of Colorado Boulder aims to get to the bottom of why, as the saying goes, you get a "skip in your step" when you're happy.

Scientists at the University of California, Irvine's School of Pharmacy & Pharmaceutical Sciences have discovered how muscle stem cells "flip a switch" to rebuild damaged muscle – a finding that could help address muscle loss linked to aging, injury and widely used weight-loss medications.

At Super Bowl parties, weddings, Independence Day cookouts and Thanksgiving dinners, people celebrate with large spreads of food.

Refugee and immigrant children are less likely to visit the emergency department (ED) for minor illnesses (e.g., respiratory infections) compared to children born in Ontario, according to a new study from ICES and The Hospital for Sick Children (SickKids).

When the immune system detects a harmful or foreign agent it triggers an inflammatory response small proteins called chemokines direct immune cells to the site of the injury or infection, resulting in the invader being inactivated.

Hantaviruses, transmitted from rodents to people, have a death rate approaching 40%. They're found around the world, and because there are no approved vaccines or treatments, they're among the pathogens of highest concern for future pandemics.

The pathogens that cause tropical diseases rely on an essential protein that is absent from all other organism. This discovery opens the possibility for targeted treatment.