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Researchers discover new genetic cause of hereditary optic atrophy
A research team from the Medical University of Vienna and the Medical University of Graz has discovered a previously unknown genetic cause of hereditary optic atrophy, a degenerative disease of the optic nerve associated with gradual loss of vision.
Maternal exposure to PM2.5 during pregnancy linked to lower myelination in newborns' brains
A study published in Environment International concludes that air pollution during pregnancy is associated with slower brain maturation in newborns.
Uncovering a molecular weakness in Ewing sarcoma for targeted therapy
A research team at the Seville Biomedical Institute (IBis) has identified a new molecular mechanism that explains the high sensitivity of Ewing sarcoma (an aggressive bone cancer that mainly affects children and adolescents) to certain chemotherapy drugs, such as irinotecan.
Experts call for action against imposter participants in health studies
Imposter participants threaten the integrity of health research and, by extension, the policies and clinical decisions built on it, warn experts in The BMJ today.
Mass General Brigham study shows US obesity could jump from 40% to 70%
The prevalence of obesity in the United States could rise sharply under a new definition of obesity released earlier this year by the Lancet Diabetes and Endocrinology Commission.
Combining prebiotics and omega-3 is key to better immune and metabolic health
A new study, led by experts at the University of Nottingham, has found that combining certain types of dietary supplements is more effective than single prebiotics or omega-3 in supporting immune and metabolic health, which could lower the risk of conditions linked to chronic inflammation.
Why community clubs must focus on parents to halt youth drop-out
Community sporting clubs must rethink how they engage parents if they want to stop the slide in young people dropping out of sport, according to new Flinders University research.
Fatty acids found to be a primary driver of triple-negative tumor growth
A team from Huntsman Cancer Institute at the University of Utah (the U) has found that triple-negative breast cancer is fueled by lipids and that these fatty acids are a key feature of obesity that promote tumor growth.
Researchers uncover TRAT1's central role in T helper cell function
Researchers at the Medical University of Vienna have taken a closer look at a previously largely unknown component of the immune system: the protein molecule TRAT1 (T Cell Receptor Associated Transmembrane Adaptor 1) plays a central role in how so-called T helper cells (a specialised subgroup of immune cells) distinguish between attack and self-control - an important mechanism for restraining inflammation and preventing autoimmune diseases. The findings have recently been published in the journal Cell Communication and Signaling.
New European trial tests subcutaneous EEG technology for people with epilepsy
A new clinical trial co-led by researchers at FutureNeuro and RCSI University of Medicine and Health Sciences is investigating how advanced brain monitoring could improve the diagnosis and management of epilepsy.
One in four U.S. hepatologists screen positive for unhealthy alcohol use
One in four hepatologists in the United States screened positive for unhealthy alcohol use in a survey study conducted by UCLA.
Psychological fatigue poses major risk for returning smokers
The most reliable predictor of an ex-smoker's relapse isn't strong urges to smoke or low confidence in the ability to stay off tobacco – it's weariness with the efforts to remain a non-smoker, according to a new study published today in Addiction.
Longevity gene offers hope for children with progeria
A new breakthrough in a rare genetic disease which causes children to age rapidly has been discovered using 'longevity genes' found in people who live exceptionally long lives - over 100 years old.
LGBTQ+ adolescents face higher rates of mental health challenges and substance use
New research from the University of Delaware finds that LGBTQ+ adolescents in Delaware face strikingly higher rates of mental health challenges and substance use compared to their peers.
Low-dose steroids show promise for treating severe kidney inflammation
Will it be possible to treat severe kidney inflammation with fewer drugs in the future? A new study by the University Hospital Bonn (UKB), the University of Bonn, and the University of Hamburg gives cause for hope.
Testosterone does not alter economic decision making in men
Testosterone has long been linked to risk-taking, generosity, and competitiveness. But a new large-scale study - the biggest of its kind - finds that men given testosterone made the same economic choices as those given a placebo.
Experimental gene therapy restores immune system function in children with genetic immune disorder
An experimental gene therapy developed by researchers at UCLA, University College London and Great Ormond Street Hospital has restored and maintained immune system function in 59 of 62 children born with ADA-SCID, a rare and deadly genetic immune disorder.
Does eating watermelon lower blood pressure?
Researchers reviewed the role of watermelon as a natural source of L-citrulline and its potential to improve cardiovascular health by enhancing nitric oxide production. While promising effects on blood pressure and arterial stiffness were seen in at-risk groups, long-term and dose-specific studies are still needed to confirm clinical benefits.
Aerobic exercise found to be most effective for knee osteoarthritis
For patients with knee osteoarthritis, aerobic activities such as walking, cycling, or swimming are likely to be the best exercise for improving pain, function, gait performance, and quality of life, finds a study published by The BMJ today.