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Promising findings for the treatment of patients with pulmonary arterial hypertension with a high risk of mortality
Pulmonary arterial hypertension (PAH) is a rare and severe lung disease with a life-threatening prognosis. After several positive trials, a recent study has confirmed the efficacy of a biotherapy, sotatercept.
Gut bacteria turn bile acids into allies against cancer
Bacteria naturally present in the human intestine, known as the gut microbiota, can transform cholesterol-derived bile acids into powerful metabolites that strengthen anti-cancer immunity by blocking androgen signaling, according to a preclinical study led by Weill Cornell Medicine investigators.
Nasal protein levels may predict COVID-19 risk
Higher nasal expression of ACE2 and TMPRSS2 proteins can predict future SARS-CoV-2 infection.
New genetic clues uncovered in epilepsy drug resistance
Certain common genetic changes might make some people with focal epilepsy less responsive to seizure medications, finds a new global study led by researchers at UCL and UTHealth Houston.
Modified Japanese diet shows promise for lowering blood pressure, study finds
A study of 12,213 Japanese workers found no link between hypertension and the traditional Japanese diet, but a modified version emphasizing whole grains, fruits, and dairy showed a potential protective effect. The findings highlight how modernizing traditional diets with nutrient-rich foods may combat high blood pressure.
Low vitamin D levels damage erectile health via superoxide surge, study finds
Vitamin D deficiency directly causes erectile dysfunction by increasing superoxide and reducing protective SLPI levels, as shown in human tissue and animal models. This breakthrough reveals why low vitamin D may lead to poor sexual health and resistance to standard ED treatments.
Digital technology use linked to lower risk of cognitive decline
As the first generation that interacted with digital technology reaches an age where dementia risks emerge, scientists have asked the question: Is there a correlation between digital technology use and an increased risk of dementia?
New study examines how obesity alters brain's reward circuits
Obesity is on the rise. Among U.S. adults aged 20 or older, 4 in 10 met the criteria for obesity in the most recent National Health and Nutrition Examination Survey, up from roughly 3 in 10 two decades earlier.
Blood test for tumor DNA may predict melanoma recurrence
Monitoring blood levels of DNA fragments shed by dying tumor cells may accurately predict skin cancer recurrence, a new study shows.
Mid afternoon inhaler use may improve nighttime asthma control
A single daily preventer dose of inhaled corticosteroid (beclomethasone), taken mid afternoon, may be the best timing for effective asthma control as it suppresses the usual nocturnal worsening of symptoms more effectively than dosing regimens at other times of the day, suggest the results of a small clinical trial published in the journal Thorax.
EAT-Lancet planetary diet shows no dementia risk, may protect against Alzheimer’s
In a large Swedish study, researchers found that the environmentally sustainable EAT-Lancet diet does not increase dementia risk and may lower the risk of Alzheimer’s and all-cause dementia, particularly in people without the APOE ε4 gene. The findings support the integration of sustainable diets into dementia prevention strategies.
New genetic study reveals hundreds of clues to osteoarthritis
About one in five American adults have osteoarthritis, the most common form of arthritis, according to the Centers for Disease Control and Prevention.
New analysis clarified the link between "exclusive" use of e-cigarettes and COPD
A Johns Hopkins Medicine-led analysis of medical information gathered on a diverse group of almost 250,000 people over four years has significantly clarified the link between the "exclusive" use of e-cigarettes and chronic obstructive pulmonary disease (COPD), as well as high blood pressure in a sub-group of adults 30 to 70 years of age.
Peanuts pack a punch for youth: study finds cellular benefits
Daily consumption of skin-roasted peanuts for six months led to a modest but significant increase in telomere length among young, healthy adults, while peanut butter did not show this effect.
Multi-omics analysis uncovers molecular drivers of non-viral liver cancer development
Researchers discover that inflammation and aging contribute to non-viral liver cancer development. Green tea's role in reversing some of the pathway dysregulation that may contribute to the cancer development and other therapies explored.
Breakthrough retina mapping sheds light on visual processing pathways
Vision is one of the most complex functions of our brain and requires a seamless interaction between many different brain structures to decode shapes, colours, depths, and movements and turn them into a meaningful whole.
Study offers a potential new strategy to improve treatment responses in multiple myeloma patients
Researchers at the VIB-UGent Center for Medical Biotechnology have discovered a promising strategy to improve treatment responses in multiple myeloma patients by blocking a protein that plays a key role in drug resistance.
New findings highlight a shifting landscape for weight loss and glucose managing medications
When it comes to managing weight loss and type 2 diabetes with medications, research shows that it's out with the old and in with the new.
Study reveals CT scan overuse could account for 1 in 20 new US cancers
A new study projects that CT scans performed in the US in 2023 could cause around 103,000 future cancers, potentially accounting for 5% of all new cancer diagnoses. Researchers highlight that while individual risks are small, the population impact of unnecessary or high-dose CT imaging is significant.
Multiple myeloma care improved using innovative optical genome mapping
Researchers have demonstrated the potential of the innovative optical genome mapping (OGM) technique for the diagnosis, prognosis, and therapeutic management of multiple myeloma.