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Genetic and inflammatory factors amplify the link between earlier menopause and cognitive risk
Women are significantly more likely than men to develop Alzheimer's disease. Earlier age at menopause is associated with a greater risk for late-life cognitive decline and Alzheimer's disease.
Hormone therapy does not consistently reduce menopause-related anxiety, new review finds
Anxiety is a common and significant symptom of menopause and perimenopause, largely due to hormone fluctuations. Numerous studies have focused on the potential benefits of hormone therapy in reducing anxiety.
Largest trial of adjuvant pembrolizumab in Merkel cell carcinoma reports key benefit
A new cancer clinical trial by the ECOG-ACRIN Cancer Research Group (ECOG-ACRIN) shows that a drug that utilizes the body's immune system to target and eliminate cancer cells appeared to reduce the risk of distant metastases for an aggressive form of skin cancer when given immediately after surgery, but did not significantly reduce the overall risk of recurrence, which was a co-primary endpoint of the trial.
Gender-affirming hormone therapy rewrites body proteins to match gender identity
Melbourne researchers have discovered gender-affirming hormone therapy can alter body proteins to match a person's gender identity, potentially affecting susceptibility to certain health conditions.
New chip restores reading ability for macular degeneration patients
A tiny wireless chip implanted in the back of the eye and a pair of high-tech glasses have partially restored vision to people with an advanced form of age-related macular degeneration. In a clinical trial led by Stanford Medicine researchers and international collaborators, 27 out of 32 participants had regained the ability to read a year after receiving the device.
Researchers engineer a tool to dismantle cancer's RNA-built growth hubs
In a city, coworking hubs bring people and ideas together. Inside cancer cells, similar hubs form-but instead of fueling progress, they supercharge disease. That's what researchers at the Texas A&M University Health Science Center (Texas A&M Health) have discovered inside the cells of a rare and aggressive kidney cancer.
Study reveals protein plaques in neurodegeneration function as enzymes, breaking down ATP
A new study led by Rice University's Pernilla Wittung-Stafshede has revealed that protein clumps, or plaques that clog the brain, associated with Parkinson's disease are not merely waste; they can actively drain energy from brain cells.
Digital health program increases lung cancer screening rates in high-risk individuals
A new study led by researchers at Wake Forest University School of Medicine, in collaboration with the University of North Carolina at Chapel Hill and MD Anderson Cancer Center, has found that a direct-to-patient digital health program can significantly increase lung cancer screening rates among people at high risk.
Blood biomarkers forecast long-term blood pressure improvement after adolescent bariatric surgery
A groundbreaking study published in Hypertension, the journal of the American Heart Association, has identified a set of blood-based biomarkers that can predict improvements in blood pressure five years after adolescents underwent metabolic bariatric surgery.
Study reveals high sudden cardiac death rates in female bodybuilders
Sudden cardiac death is responsible for an unusually high proportion of deaths in female bodybuilders worldwide, according to research published in the European Heart Journal today (Tuesday).
Why the first 1,000 days matter most in preventing childhood obesity
The EndObesity Consortium’s narrative review underscores that most childhood obesity risks emerge in the first 1,000 days, well before birth, highlighting gaps in parental, social, and policy interventions. Effective prevention demands preconception-focused, family-wide, and system-level strategies built on equitable public health frameworks.
Low parental omega-3 intake tied to preterm birth and neighborhood disadvantage
Researchers in Chicago found that both mothers and fathers consumed far less DHA and EPA than recommended, with lower maternal intake linked to prior preterm birth. Socioeconomic disadvantage and neighborhood opportunity also influenced omega-3 intake, highlighting disparities that affect family health potential.
Can fitness apps and wearables make children healthier? This study says yes - partly
Digital health tools such as apps, wearables, and web platforms can modestly improve children’s physical activity, diet, and weight outcomes. Shorter programs boost activity, while longer ones better support weight management, though effects on sleep and sedentary time remain unclear.
Heavy drinking fuels Alzheimer’s disease by igniting brain inflammation and protein damage
Chronic alcohol use accelerates Alzheimer’s disease (AD) progression by intensifying oxidative stress, neuroinflammation, and amyloid-tau pathology through shared molecular pathways. The review highlights emerging therapies, targeting TLR4, GSK-3β, and metabolic dysfunction, that may mitigate alcohol-induced neurodegeneration.
Physical activity linked to higher overnight glucose in pregnancy hyperglycemia
Research shows that more daytime movement in pregnant women with hyperglycemia can raise nighttime blood sugar, highlighting the need for further investigation.
Social and environmental inequality linked to risk of Alzheimer’s
The study uncovers links between neighborhood disadvantage and Alzheimer's biomarkers, stressing the importance of addressing social inequalities in healthcare.
Simple hand grip test may reveal your future obesity risk
Increased grip strength correlates with lower obesity-related disease risk, suggesting muscle power as a key factor in preclinical obesity management.
Yogurt’s impact on bone health falls short of fracture protection, review finds
This systematic review and meta-analysis found that while yogurt consumption shows a modest positive association with bone health markers, its effect on bone mineral density and fracture prevention in adults is clinically negligible. Current evidence is based solely on observational studies, with low certainty and limited characterization of yogurt products.
Mediterranean-style diets improve pelvic floor function and sexual health, review finds
This systematic review and meta-analysis of 31 studies reveals that healthy, anti-inflammatory dietary patterns, particularly the Mediterranean and DASH diets, are linked to improved sexual function and reduced incontinence symptoms in pelvic floor dysfunction. However, prospective evidence for incontinence improvement remains limited, suggesting that benefits may be mediated by metabolic and inflammatory pathways, especially in individuals with obesity or metabolic syndrome.
Low-calorie diets linked to higher psoriatic arthritis risk, genetic study suggests
This Mendelian randomization study found that low-calorie diets may slightly increase the risk of psoriatic arthritis, while vegetarian and gluten-free diets showed no causal links to psoriasis, acne, or atopic dermatitis. The findings challenge assumptions about universally beneficial dietary patterns and highlight the need for cautious interpretation of dietary interventions in inflammatory skin disease.