For citation: Ali AHA, Badawy W, Aldriweesh T, Alkhaldi SEEH, Alsulami SL, Alanazi AF, Almalki AE, Alharbi MA, Almunyif SA, Aldosari RA, Alotaibi SBS, Alqahtani RN, Almalki MAS, Almutairi RSR. Nature of Nasal Polyps among Adults in Al Kharj City: A Retrospective Study. International Journal of Biomedicine. 2026;16(1):59-63. doi:10.21103/Article16(1)_OA7
Originally published March 5, 2026
Background: Clinical and radiographic criteria are used to diagnose nasal polyps, but histopathologic examination is necessary for a definitive diagnosis. There are numerous categories for the histological classification of nasal polyps. The aim of this study was to identify the histological subtypes of nasal polyps in adult patients in Al Kharj city.
Material and Methods: Fifty-one individuals who had surgery to remove nasal polyps between January 2024 and June 2025, and whose diagnoses were verified by histological analysis, were the subject of a retrospective study based on hospital information. Males made up more than half (58.78%) of the patients. Inflammatory or allergic polyps were found in most cases (52.9%). Inverted papilloma was found in 21 cases (41.1%). Of the 51 cases, only 3 were malignant.
Conclusion: Upon histological inspection, the nasal polyps primarily exhibit an inflammatory or allergic pattern. Histopathological examination of a resected nasal polyp is often necessary to establish the definitive diagnosis, as it is challenging to detect the pathology of a nasal mass clinically.
- Allen JS, Eisma R, LaFreniere D, Leonard G, Kreutzer D. Characterization of the eosinophil chemokine RANTES in nasal polyps. Ann Otol Rhinol Laryngol. 1998 May;107(5 Pt 1):416-20. doi: 10.1177/000348949810700510. PMID: 9596221.
- Fokkens WJ, Lund VJ, Hopkins C, Hellings PW, Kern R, Reitsma S, et al. European Position Paper on Rhinosinusitis and Nasal Polyps 2020. Rhinology. 2020 Feb 20;58(Suppl S29):1-464. doi: 10.4193/Rhin20.600. PMID: 32077450.
- Fan Y, Jiao Q, Zhou A, Liu J. [Correlation between chronic sinusitis subtypes and basophil levels in peripheral blood]. Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2023 Apr;37(4):293-296;301. Chinese. doi: 10.13201/j.issn.2096-7993.2023.04.011. PMID: 36987961; PMCID: PMC10406586.
- Hellings PW, Borrelli D, Pietikainen S, Agache I, Akdis C, Bachert C, Bewick M, Botjes E, Constantinidis J, Fokkens W, Haahtela T, Hopkins C, Illario M, Joos G, Lund V, Muraro A, Pugin B, Seys S, Somekh D, Stjärne P, Valiulis A, Valovirta E, Bousquet J. European Summit on the Prevention and Self-Management of Chronic Respiratory Diseases: report of the European Union Parliament Summit (29 March 2017). Clin Transl Allergy. 2017 Dec 27;7:49. doi: 10.1186/s13601-017-0186-3. PMID: 29299230; PMCID: PMC5745781.
- Lathi A, Syed MM, Kalakoti P, Qutub D, Kishve SP. Clinico-pathological profile of sinonasal masses: a study from a tertiary care hospital of India. Acta Otorhinolaryngol Ital. 2011 Dec;31(6):372-7. PMID: 22323848; PMCID: PMC3272868.
- Valera FC, Anselmo-Lima WT. Evaluation of efficacy of topical corticosteroid for the clinical treatment of nasal polyposis: searching for clinical events that may predict response to treatment. Rhinology. 2007 Mar;45(1):59-62. PMID: 17432072.
- Enache I, IoniȚĂ E, Mitroi M, Anghelina F, MogoantĂ C, Ciolofan S, CĂpitĂnescu A, Stepan A, Simionescu C. Histopathological Features of Chronic Rhinosinusitis with Nasal Allergic Polyps. Curr Health Sci J. 2020 Jan-Mar;46(1):66-71. doi: 10.12865/CHSJ.46.01.09. Epub 2020 Mar 31. PMID: 32637167; PMCID: PMC7323723.
- Bernstein JM, Gorfien J, Noble B. Role of allergy in nasal polyposis: a review. Otolaryngol Head Neck Surg. 1995 Dec;113(6):724-32. doi: 10.1016/s0194-5998(95)70012-9. PMID: 7501384.
- Abdulla MS, Janardhan K, Lakshmi VP, John R. A Retrospective Study on Histomorphological Analysis of Sinonasal Polyps at A Tertiary Care Centre in A Rural Area of South India. Int J Trop Med. 2024 May 2;18:83-9.
- Lanza DC, Kennedy DW. Current concepts in the surgical management of nasal polyposis. J Allergy Clin Immunol. 1992 Sep;90(3 Pt 2):543-5; discussion 546. doi: 10.1016/0091-6749(92)90182-2. PMID: 1527347.
- Chen SH, Wu CS, Chan KH, Hongh YT, Shun CT, Liu CM. Primary sinonasal non-Hodgkin's lymphoma masquerading as chronic rhinosinusitis: an issue of routine histopathological examination. J Laryngol Otol. 2003 May;117(5):404-7. doi: 10.1258/002221503321626483. PMID: 12803794.
- Kirtsreesakul V. Nasal polyps: the relationship to allergy, sinonasal infection and histopathological type. J Med Assoc Thai. 2004 Mar;87(3):277-82. PMID: 15117044.
- Kitapçi F, Muluk NB, Atasoy P, Koç C. Role of mast and goblet cells in the pathogenesis of nasal polyps. J Otolaryngol. 2006 Apr;35(2):122-32. doi: 10.2310/7070.2005.5004. PMID: 16527032.
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Received January 1, 2026.
Accepted February 12, 2026.
©2026 International Medical Research and Development Corporation.




