Pregnancy-Associated Synchronous Ovarian and Gastric Cancer

CASE REPORT
E.M. Zhulina, D.S. Zhulin, D.V. Kromka, N.V. Bezgodova, S.S. Naumov, N.V. Krakhmal, A.L. Chernyshova, M.V. Zavyalova, S.V. Vtorushin

 
For citation: Zhulina EM, Zhulin DS, Kromka DV, Bezgodova NV, Naumov SS, Krakhmal NV, Chernyshova AL, Zavyalova MV, Vtorushin SV. Pregnancy-Associated Synchronous Ovarian and Gastric Cancer. International Journal of Biomedicine. 2025;15(1):210-214. doi:10.21103/Article15(1)_CR1
 
Originally published March 5, 2025

Abstract: 

The occurrence of malignant neoplasms during pregnancy presents an exceptionally challenging clinical scenario, encompassing complex medical decisions alongside crucial social and ethical considerations. The simultaneous development of multiple primary carcinomas is particularly rare, especially when occurring during pregnancy or within 12 months postpartum. Synchronous cancers are defined as two or more independent tumors detected simultaneously or within a six-month interval—representing an uncommon clinical phenomenon of significant scientific interest. While cases of pregnancy-associated synchronous cancers have been documented, successful treatment options remain limited. Our literature review revealed no previously reported cases of synchronous ovarian and gastric cancer developing during pregnancy. This article presents a unique clinical case that highlights both the diagnostic challenges and the severely limited therapeutic options available for patients with pregnancy-associated malignancies, particularly in such a rare combination of synchronous primary tumors. This case contributes valuable insights into the management of complex pregnancy-associated malignancies and underscores the need for improved diagnostic and therapeutic strategies.

Keywords: 
malignant neoplasm • pregnancy • synchronous cancer
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Received January 16, 2025.
Accepted February 26, 2025.
©2025 International Medical Research and Development Corporation.