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A pair of proteins, YAP and TAZ, has been identified as conductors of bone development in the womb and could provide insight into genetic diseases such as osteogenesis imperfecta, known commonly as "brittle bone disease."

As if starting life with a potentially disabling genetic blood disease wasn't enough, a study shows that almost two-thirds of babies born with sickle cell disease are born to mothers who live in disadvantaged areas.

Having bipolar disorder – a serious mental illness that can cause both manic and depressed moods – can make life more challenging.

In a study designed to better understand sudden, unexpected deaths in young children, which usually occur during sleep, researchers have identified brief seizures, accompanied by muscle convulsions, as a potential cause.

Performed early – at the time of amputation – a procedure called targeted muscle reinnervation (TMR) can reduce pain scores and prevent complications related to abnormal nerve regrowth, suggests a study in the January issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS). The journal is published in the Lippincott portfolio by Wolters Kluwer.

Microbiota-reactive T cells trigger colitis in mice harboring the microbiota of wild-caught mice following CTLA-4 blockade, according to a new study that reveals a major mechanism by which anti-CTLA-4 antibodies induce inflammatory toxicities during antitumor immune checkpoint inhibitor therapies.

Study found that the link between screen viewing and drawing ability in young French children is influenced by socioeconomic factors, rather than a direct causal relationship between screen time and cognitive development.

An international collaborative study led by postdoctoral scientist, Dr. Maimuna Paul, and child neurologist, Dr. Hsiao-Tuan Chao, an assistant professor at Baylor College, a faculty member with the Cain Pediatric Neurology Research Foundation Laboratories at the Jan and Dan Duncan Neurological Research Institute (Duncan NRI) at Texas Children's Hospital, and an investigator at the McNair Medical Institute with The Robert and Janice McNair Foundation, recently discovered that variants in the PPFIA3 gene cause a previously unknown syndromic neurodevelopmental disorder.

In a first for USC Stem Cell scientists, the laboratory of Giorgia Quadrato, an assistant professor of stem cell biology and regenerative medicine, has pioneered a novel human brain organoid model that generates all the major cell types of the cerebellum, a hindbrain region predominantly made up of two cell types necessary for movement, cognition, and emotion: granule cells and Purkinje neurons.

A cohort study in JAMA Network Open found a decrease in urinary tract infection (UTI) diagnoses among children during the early COVID-19 pandemic without an increase in disease severity, suggesting a potential reduction in over- or misdiagnosis.

A study analyzing data from the Genitourinary Medicine Clinic Activity Dataset in England shows a 64% increase in gonorrhea diagnoses following the relaxation of COVID-19 restrictions, despite only a 5.6% increase in STI testing, suggesting that social distancing may have suppressed STI transmission.

A study in Taiwan involving 3,062 thyroid cancer patients and 9,186 controls finds that HPV infection more than doubles the risk of developing thyroid cancer, providing the first evidence of a carcinogen for this common endocrine cancer.