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Ancient DNA reveals first prehistoric cases of Turner and Jacob's syndromes
Ancient DNA reveals first prehistoric cases of Turner and Jacob's syndromes, with new technique enhancing chromosome analysis
UVA researchers join international consortium to study climate-related childhood diarrhea
UVA Health researchers have joined a new international consortium that will work to understand how climate change could affect dangerous diarrheal diseases, a leading cause of death for children under 5 years old.
New analysis of cancer cells identifies 370 targets for smarter, personalized treatments
A new, systematic analysis of cancer cells identifies 370 candidate priority drug targets across 27 cancer types, including breast, lung and ovarian cancers.
Increased cholesterol levels in adolescence linked to early heart damage
Heart disease is the number one killer disease in the world. Elevated cholesterol and dyslipidaemia in children and adolescents increase the risk of premature death in the mid-forties and subclinical atherosclerosis in the mid-twenties.
Planning prompts show promise in improving prescribing safety
Physicians who are notified that a patient has died of a drug overdose are more judicious in issuing controlled substances if the notification includes a plan for what to do during subsequent patient visits, according to a study published today in Nature Communications.
Leveraging nutritional interventions for effective TB control
Tuberculosis (TB) is the leading infectious killer worldwide, with 10.6 million cases and 1.6 million deaths in 2021 alone.
Study explains why "being in love" makes us tunnel visioned
Love is blind, the saying goes, and thanks to a world-first Australian study, we are now a step closer to understanding why.
Exploring the link between pancreatic islet cell loss and age-related health conditions
Researchers from Tokyo Metropolitan University have studied pancreatic islet cell loss in people with no previous pancreatic problems. They identified key trends in the types of cells lost due to islet cell loss in different age groups and sexes, finding that ICL in the elderly population was largely due to insulin-producing beta cell loss.
New study offers hope for reducing malaria in pregnant women living with HIV
In women living with HIV, preventive treatment with DHA-PPQ is a safe and effective strategy to prevent malaria during pregnancy, according to the final results of MAMAH, a clinical trial funded by the European & Developing Countries Clinical Trials Partnership (EDCTP) and coordinated by the Barcelona Institute for Global Health (ISGlobal), an institution supported by "la Caixa" Foundation.
Swedish blood donor study reveals high prevalence of undiagnosed TBE infections
The number of infections by the tick-borne TBE virus that are not detected by health services is far higher than previously assumed.
RBM5 identified as key regulator of HOXA9 in acute myeloid leukemia
The protein HOXA9 is overexpressed in most acute myeloid leukemia (AML) cases and is associated with poor patient outcomes.
FDA-approved drug may help to decrease pain after surgery, study finds
Researchers in the Department of Anesthesia and Perioperative Medicine at the Medical University of South Carolina (MUSC) have found that an FDA-approved drug may help to decrease pain after surgery.
Pazopanib activity confirmed in EWSR1-NFATC2 bone sarcoma
A new case report was published in Oncoscience (Volume 10) on September 20, 2023, entitled, "Activity of pazopanib in EWSR1-NFATC2 translocation-associated bone sarcoma."
Urinary incontinence associated with higher odds of future disability
If you are one of the 30% to 50% of women experiencing urinary incontinence, new research suggests that it could turn into a bigger health issue.
A biological signature of desire helps explain the selective nature of pair bonds
Hop in the car to meet your lover for dinner and a flood of dopamine-; the same hormone underlying cravings for sugar, nicotine and cocaine -; likely infuses your brain's reward center, motivating you to brave the traffic to keep that unique bond alive.
Drinkable, carbon monoxide-infused foam supercharges cancer therapy
Did smokers do better than non-smokers in a clinical trial for an experimental cancer treatment? That was the intriguing question that led University of Iowa researchers and their colleagues to develop a drinkable, carbon monoxide-infused foam that boosted the effectiveness of the therapy, known as autophagy inhibition, in mice and human cells.
Researchers uncover role of persister cells in antibiotic resistance
Antibiotic overuse can lead to antibiotic resistance, but classic antibiotic resistance might not completely explain why antibiotics sometimes fail.
Obesity linked to 73% higher risk of precursor to blood cancer
Individuals with obesity are more likely to have monoclonal gammopathy of undetermined significance (MGUS), a benign blood condition that often precedes multiple myeloma, according to new research published in Blood Advances.
AI algorithm may better support clinical care and research by identifying patients with adverse social determinants of health
A new study explores the use of large language models (LLMs) to obtain such vital data from EHRs to improve research outcomes and offer better clinical care.
Study reports a prominent increase in substance use and cardiovascular disease‐related mortality in the United States between 1999 and 2019
Researchers evaluated trends in substance use and cardiovascular disease-related mortality in the United States using Centers for Disease Control and Prevention data.