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New research highlights potential of cytisine for global smoking cessation efforts

Rss Feed - Tue, 01/02/2024 - 12:34
A new study published in Addiction has found that cytisine, a low-cost, generic stop-smoking aid that has been used in eastern Europe since the 1960s, increases the chances of successful smoking cessation by more than two-fold compared with placebo and may be more effective than nicotine replacement therapy. It has a benign safety profile, with no evidence of serious safety concerns.

$550,000 grant supports VT researchers to study the effects of changing food spending patterns

Rss Feed - Tue, 01/02/2024 - 12:03
After a long day, there's the age-old question of do we eat out or stay in? Over the last decade, that answer has increasingly shifted to eating out.

Healthy fats from fish and nuts may slow lung scarring, delay transplants

Rss Feed - Tue, 01/02/2024 - 10:07
Could healthy fats found in nuts and fish slow the progression of potentially deadly lung scarring known as pulmonary fibrosis and delay the need for lung transplants?

Study reveals novel neural coding mechanism for transferring perceptual information to memory

Rss Feed - Tue, 01/02/2024 - 09:38
Our memories are rich in detail: we can vividly recall the color of our home, the layout of our kitchen, or the front of our favorite café. How the brain encodes this information has long puzzled neuroscientists.

Adolescent obesity heightens the risk of early chronic kidney disease in young adulthood

Rss Feed - Tue, 01/02/2024 - 09:24
New study finds that adolescent obesity significantly heightens the risk of developing early chronic kidney disease in young adulthood. Even those with high-normal BMI are at risk.

Targeted ocular spectroscopy shines new light on retinal health

Rss Feed - Mon, 01/01/2024 - 18:14
Study demonstrates the effectiveness of targeted ocular fluorescence spectroscopy for analyzing the eye fundus, offering potential advancements in diagnosing and treating eye diseases.

How immune cells shape our earliest breaths

Rss Feed - Mon, 01/01/2024 - 18:02
Study profiles the development of immune cells in human lungs during embryonic and fetal stages, revealing their influence on epithelial cell fate and lung development.

Study reveals burnout and professional dissatisfaction driving physicians to leave their practices

Rss Feed - Mon, 01/01/2024 - 17:51
Study investigates the prevalence of burnout, professional fulfillment, and intention to leave among physicians, revealing significant variations based on gender, age, race, and specialty.

Phthalate exposure before conception linked to reduced fertility and hormonal imbalances in women

Rss Feed - Mon, 01/01/2024 - 17:39
Study examines the impact of preconception phthalate exposure on women's reproductive health, revealing associations with reduced fecundability, hormonal changes, and increased oxidative stress and inflammation.

"NK cell-engaging nanodrones" can selectively target and kill cancer cells

Rss Feed - Fri, 12/29/2023 - 22:29
A groundbreaking study led by Professor Sebyung Kang and Professor Sung Ho Park in the Department of Biological Sciences at UNIST has unveiled a remarkable breakthrough in cancer treatment.

Mettl3 guides CD8 T cells to eliminate infected cells with maximum efficiency

Rss Feed - Fri, 12/29/2023 - 22:13
This study is led by Dr. Shuyang Yu (College of Biological Sciences, China Agricultural University), Dr. Jingyu Xu (The Collaborative Innovation Center of Tissue Damage Repair and Regeneration Medicine of Zunyi Medical University) and Dr. Xuguang Du (College of Biological Sciences, China Agricultural University) and illustrated the key role of Mettl3 in CD8 T cell response during acute infection model.

New study expands immunotherapy eligibility for colorectal and endometrial cancer patients

Rss Feed - Fri, 12/29/2023 - 16:30
A new study shows thousands more patients diagnosed with colorectal and endometrial cancers could benefit from immunotherapy than are currently offered it.

Johns Hopkins researchers find minimal regret after gender affirming surgery

Rss Feed - Thu, 12/28/2023 - 22:17
In a Viewpoint article published Dec. 27, 2023, in JAMA Surgery, three Johns Hopkins researchers urge the medical community to dismiss a widely held, but scientifically unsupported belief that many people who are transgender and gender diverse (TGD), and undergo gender affirming surgery (GAS), later regret their decision to undergo such procedures.

'Visual system' protein appears to be key for stabilizing the body's circadian rhythms

Rss Feed - Thu, 12/28/2023 - 21:56
Scientists at the Johns Hopkins University School of Medicine and the National Institutes of Health have identified a protein in the visual system of mice that appears to be key for stabilizing the body's circadian rhythms by buffering the brain's response to light.

$15 million NCI grant awarded to investigate a type of radiation therapy for hard-to-treat cancers

Rss Feed - Thu, 12/28/2023 - 21:44
The Radiopharmaceutical Therapy and Dosimetry Lab at Johns Hopkins Medicine, headed by George Sgouros, Ph.D., has been awarded a $15 million grant, to be dispersed over the next five years, from the National Cancer Institute at the National Institutes of Health.

GFH009 disrupts growth signals and triggers apoptosis in hematologic malignancies

Rss Feed - Thu, 12/28/2023 - 21:28
A new research paper was published in Oncotarget's Volume 14 on December 20, 2023, entitled, "The pharmacodynamic and mechanistic foundation for the antineoplastic effects of GFH009, a potent and highly selective CDK9 inhibitor for the treatment of hematologic malignancies."

Angelica gigas extract emerges as a potential treatment for vascular disease

Rss Feed - Thu, 12/28/2023 - 21:07
A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 23, entitled, "Angelica gigas extract inhibits acetylation of eNOS via IRE1α sulfonation/RIDD-SIRT1-mediated posttranslational modification in vascular dysfunction."

New insights on better diagnosis and treatment of ischemic cholecystitis

Rss Feed - Thu, 12/28/2023 - 20:59
Ischemic cholecystitis is a form of gallbladder inflammation that occurs without gallstones or another form of external compression.

Lisocabtagene maraleucel: A cost-effective second-line treatment for relapsed/refractory DLBCL

Rss Feed - Thu, 12/28/2023 - 20:07
Lisocabtagene maraleucel (liso-cel), a CAR T-cell therapy, is a cost effective second line treatment for relapsed and refractory (hard to treat) diffuse large B-cell lymphoma (r/r DLBCL), according to a study published today in Blood Advances.

Integrated care may not be the silver bullet for mental health treatment, study finds

Rss Feed - Thu, 12/28/2023 - 20:01
Health care systems in the United States have gradually embraced the concept that mental health should be treated on par with physical health, especially in light of increased rates of anxiety and depression during and after the COVID-19 pandemic.