The Effect of Peptide YY3-36 in Body Mass Regulation in Patients with Exogenous Constitutional Obesity

Yuliya Y. Vlasova, PhD¹²*, Alexander S. Ametov PhD, ScD³

¹Samara Medical University “REAVIZ”, Samara, Russian Federation

²Sigmund Freud University, Vienna, Austria

³Russian Academy of Postgraduate Medical Education, Moscow, Russian Federation

*Corresponding author: Assoc. Prof. Yuliya Y. Vlasova, PhD, Department of Clinical Medicine and Endocrinology, Samara Medical University “REAVIZ”, Samara, Russian Federation; Doctoral Program student, Sigmung Freud University. Neustiftgasse 96/1/24 A-1070, Vienna, Austria. Tel: 436765359446 Fax: 4317894098. E-Mail:vlasova.yuliya@gmail.com

Abstract: 

The article deals with PYY3-36 level in the blood serum of patients suffering from exogenous constitutional obesity and overweight, as well as its role in the process of the body mass growth. Among the 327 patients diagnosed with obesity and overweight, particularly those with Class I and II degrees of obesity (p<0.05) showed a significantly increased level of PYY3-36. The highest PYY3-36 level was observed in those with the Class II or second degree of obesity (p<0.05). Exogenous Constitutional Obesity is accompanied by a significant increase in PYY3-36 in patients with Class I and II degrees of obesity.

Keywords: 
obesity; PYY3-36.
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Int J Biomed. 2012; 2(1):26-30. © 2012 International Medical Research and Development Corporation. All rights reserved.