Feed aggregator

A new ICES study has found that 1.74 million patients in Ontario are attached to family physicians aged 65 or older, and that many of those patients are elderly and have complex medical needs.

Investigating tirzepatide's role in Alzheimer's reveals its potential to improve brain function and reduce inflammation, linking diabetes and neurodegeneration.

Lead author Claire Morton, MD, and senior author Christina Ahn Minami, MD, MS, both of the Department of Surgery at Brigham and Women's Hospital, published a paper in Current Breast Cancer Reports "Survivorship Issues in Older Adults with Breast Cancer.

Huntington's disease has long defied attempts to rescue suffering neurons. A new study in Cell Reports shows that transplanting healthy human glial progenitor cells into the brains of adult animal models of the disease not only slowed motor and cognitive decline but also extended lifespan.

Qureight, a deep-learning analytics company accelerating drug development through AI-powered data curation, today announced that its digitally-twinned synthetic control arm has been used in a breakthrough clinical trial application in place of a human placebo group, marking a world-first in lung disease research.

Mursla Bio, a leader in Extracellular Vesicle (EV) science on a mission to advance precision diagnostics and significantly improve cancer outcomes for at-risk patients, today announced the commercial launch of its AI Precision Medicine Platform, alongside a pre-print reporting the first validated method for isolating hepatocyte EVs from plasma for organ-specific proteomic and miRNA profiling. Mursla Bio is engaging with potential partners to apply its Platform to additional disease areas, biomarker discovery and IV

Sphere Bio, a leading provider of picodroplet-based microfluidics for functional single-cell analysis and isolation, today announced the appointment of Redbert Biotechnology (张伟) as its exclusive distribution partner in China.

Evosep, a global leader in robust, high-throughput proteomics technologies, has been selected as the proteomics platform provider for the P4ML - OMICAssist Study—the world's largest multi-omic precision medicine initiative, launched by P4ML alongside its strategic academic, health regulatory, and semi-state partners in the United Arab Emirates.

A new grant from the National Institutes of Health (NIH) will help Wayne State University researchers explore potential connections between per- and polyfluoroalkyl substances (PFAS) exposure and adverse effects on male reproductive health.

Six out of ten people with type 2 diabetes had fatty liver in a new study from Linköping University. Of these, only a small percentage had developed more severe liver disease.

Liver transplant is a lifesaving surgery, but a significant number of patients experience organ rejection or other complications.

Bladder tumors that have been excluded from clinical trials have a few things in common that could lead to new therapies.

A study reveals Australian supermarkets' catalogs push junk food for infants, raising concerns about marketing practices and the need for stricter regulations.

Researchers uncovered how estrogen heightens gut sensitivity in females by activating PYY-secreting L-cells, which stimulate serotonin release from EC cells. This paracrine circuit intensifies pain signaling and may explain the sex bias in conditions like IBS.

Replacing one daily serving of commonly eaten fruits like apples or bananas with berries significantly boosts nutrient density in USDA dietary patterns. The modeling analysis showed notable gains in anthocyanins, fiber, and vitamins, with only modest cost increases.

A large longitudinal study found that pesticide exposure and caffeinated soda intake were linked to more severe motor symptoms in idiopathic Parkinson’s disease (iPD). In contrast, black tea consumption was associated with milder symptoms in patients with LRRK2-related Parkinson’s disease (LRRK2-PD).

Children with acute COVID-19 and MIS-C show significant disruptions in lipid metabolism, including patterns resembling adult severe COVID-19. These findings highlight potential long-term cardiovascular risks in pediatric SARS-CoV-2 cases and underscore the need for follow-up care.

Multiple sclerosis (MS) affects an estimated 2.3 million people worldwide. Approximately 80% of people with MS have inflammation in the cerebellum, the part of the brain that helps control movement and balance, potentially leading to tremors, poor coordination, and trouble with motor control.

Exposure to mycotoxins – a broad group of harmful substances produced by mold – during pregnancy may impact placental function, which could result in lower birthweight in humans, according to Rutgers Health researchers.