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Onerous caring responsibilities reduce brain function for people aged 50 and over, whereas light caring duties can actually be beneficial to middle-aged and older people's mental abilities, a new UCL study finds.

Mothers who work in jobs where they are frequently exposed to toxic chemicals or experience high stress have higher odds of having a child with autism spectrum disorder (ASD), suggest the findings of original research published online in the journal Occupational & Environmental Medicine.

A new multisite study published in Nature Mental Health found that using cannabis and tobacco together increases the risk of developing psychotic disorders like schizophrenia among those considered high risk.

A research team from the Istituto Italiano di Tecnologia (IIT-Italian Institute of Technology), in collaboration with the IRCCS Istituto Giannina Gaslini in Genoa (Italy), has demonstrated that traumatic experiences occurring at specific stages of life - particularly from childhood through the early years following adolescence - have persistent effects on brain development and adult behavior.

Implantable cytokine factories designed to deliver immunotherapy directly at the site of disease have taken an important step toward clinical reality.

Researchers have uncovered a fundamental rule that governs how genes are physically arranged inside the cell nucleus, and how disruptions to that organization can contribute to human disease.

Predicting whether a healthy 45-year-old will struggle to climb stairs or walk a decade later has long been a challenge for geriatric medicine.

Targeted protein degradation has become one of the most promising strategies in modern drug discovery, enabling scientists to eliminate disease-causing proteins instead of merely blocking them.

Diabetes is the most common and serious chronic disease worldwide, characterized by insufficient insulin to maintain proper blood glucose levels.

Chromosomes carry genetic information for biological sex, which generally assigns women two X chromosomes and men XY chromosomes.

A large retrospective cohort study of adult female breast cancer patients found that GLP-1 receptor agonist use was associated with better all-cause survival and recurrence-free survival in patients with obesity or type 2 diabetes. The strongest associations were seen versus non-use in obesity and versus insulin or metformin in type 2 diabetes, while comparisons with SGLT2 inhibitors were less consistent and require further study.

A JAMA Network Open study found that the US recorded 12.7 million excess deaths compared with 17 peer high-income countries between 1999 and 2022. Circulatory and metabolic diseases drove much of the burden, while drug poisonings, alcohol-related deaths, and suicide sharply widened the gap among younger Americans.

A macroeconomic modelling study across 190 countries and territories estimates that diabetes could reduce global economic output by INT$5.177 trillion between 2021 and 2050. Most projected losses stem from diabetes-related disability and morbidity, with high-income countries facing the largest dollar losses and low- and middle-income countries carrying most of the disease burden.

Older adults in Colorado were drawn to edible cannabis mainly to manage sleep problems, pain, anxiety, or depression, often after concerns about conventional medicines or limited relief from other treatments. Most participants preferred THC-CBD combination products, but they remained uncertain about dosing, impairment, effectiveness, and how to choose the right cannabinoid ratio.

An international research group recently demonstrated that the antibody NG101 promotes the regeneration of damaged spinal cord tissue.

New research, from King's College London and the University of Porto, has mapped the histamine system in the brain. Histamine, a molecule more commonly associated with allergies, plays a separate but poorly understood role in brain function.

Researchers from the Hebrew University of Jerusalem and the Weizmann Institute of Science have identified a previously unrecognized defense mechanism in the intestine, showing that intestinal stem cells can actively respond to Salmonella infection and help protect the gut from bacterial invasion.

Girls born to mothers with higher insulin resistance during the third trimester are more likely to have more abdominal fat at age 7, according to research presented at the 28th European Congress of Endocrinology in Prague.

MOZAIC leverages deep learning to optimize fecal microbiota transplantation, enhancing treatment efficacy through precise donor-recipient microbiome matching.

Research shows FoMO influences addictive eating, with anxiety heightening reward-driven cravings for ultra-processed foods and compulsive overeating.