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Predictive models identify high-risk liver cancer recurrence
Liver cancer is one of the world's deadliest malignancies, ranking as the third leading cause of cancer-related death.
Ateneo scientists advance toward a vaccine for stomach ulcers
Since ancient times, it was thought that painful stomach ulcers were caused by eating spicy foods or having an unhealthy diet.
Combination strategy may optimize interferon-based therapy for chronic hepatitis B
Peginterferon-α treatment exhibits low rates of the serological conversion rate of hepatitis B e antigen (HBeAg) and the negative conversion rate of hepatitis B virus (HBV) DNA, with significant myelosuppression leading to treatment discontinuation in some patients.
New model tracks disease spread through daily commuting
For countless millions across the globe, commuting to work or school is an everyday routine. But during a pandemic, the practice can contribute enormously to the spread of infectious disease, a fact that many traditional metapopulation models often overlook because they are designed primarily for migration and treat people as if they rarely move locally.
Breakthrough enables large-scale cultivation of blood vessel cells
Scientists have discovered a method to induce human endothelial cells from a small biopsy sample to multiply in the laboratory, producing more than enough cells to replace damaged blood vessels or nourish organs for transplantation, according to a preclinical study by Weill Cornell Medicine investigators.
Estradiol and estriol may protect nerve function in multiple sclerosis
About 100,000 of the estimated million people in the United States with multiple sclerosis (MS) have a progressive form of the disease, with symptoms that worsen continuously or after periods of remission.
Children living near the Salton Sea face declining lung function
Children living near the Salton Sea, in Southern California's desert region of Imperial County, are experiencing poorer lung function than children exposed to less wind-blown dust, according to a new study led by researchers at the University of California, Irvine's Joe C. Wen School of Population & Public Health.
Age alone may not predict outcomes in acute myeloid leukemia
An international study conducted by the Alliance for Clinical Trials in Oncology and the Acute Myeloid Leukemia Cooperative Group reveals that age-based classifications in the treatment of acute myeloid leukemia (AML) may be outdated and overly simplistic.
New report calls for urgent transformation of UK food system by 2050
Rapid and urgent action on food is needed if the UK is to reboot its flagging economy, save the NHS billions, ensure national food security, and meet climate commitments, according to a new report.
Scientists uncover how cellular switches guide memory formation
When we form a memory, brain cells need to deliver supplies to strengthen specific neural connections. A new study from MPFI and Weill Cornell Medicine has revealed how two cellular switches, Rab4 and Rab10, direct supplies to where they are needed.
Why improving LE8 scores could save young adults from diabetes
Young adults with prediabetes who maintained higher Life’s Essential 8 (LE8) cardiovascular health scores were far less likely to progress to type 2 diabetes over 13 years. Ideal LE8 profiles, particularly healthy weight, blood pressure, physical activity, and sleep, were strongly associated with regression to normal glucose levels.
Discovery of CPD gene mutations sheds light on rare congenital hearing loss
Mutations in a gene known as CPD play a crucial role in a rare form of congenital hearing loss, an international team of researchers has discovered.
Rising antibiotic resistance is putting routine infections back in the danger zone
Global surveillance data from over 23 million infections reveal persistently high and uneven antibiotic resistance, with the greatest burden in regions lacking diagnostic capacity and robust health systems. WHO warns that without urgent action on surveillance, stewardship, and equitable access to effective antibiotics, AMR will continue to undermine modern healthcare worldwide.
Study explores how losing the Y chromosome fuels bladder cancer aggressiveness
University of Arizona Cancer Center researchers will study the potential effects of the loss of the Y chromosome in the development and progression of bladder cancer thanks to a grant of up to $6.5 million over seven years from the National Cancer Institute.
Loneliness and isolation associated with higher death risk in cancer patients
Loneliness and social isolation are linked to a heightened risk of death from cancer as well as from all causes among those with the disease, finds a pooled data analysis of the available research published online in the open access journal BMJ Oncology.
Voter health trends reveal strong backing for Reform UK
Poorer health is linked to a higher proportion of votes for the populist right wing political party, Reform UK, indicates an analysis of the 2024 general election voting patterns in England, published online in the open access journal BMJ Open Respiratory Research.
Scientists revive diabetic beta cells, revealing a new path to restore insulin function
Researchers demonstrated that pancreatic β cells from type 2 diabetes donors can partially regain glucose responsiveness when cultured outside the diabetic environment. This recovery, driven by specific gene expression changes, identifies JAK inhibitors as potential therapeutic candidates to restore β-cell function.
How shifting antibodies fuel aging and the new therapies aiming to slow it
This review uncovers how aging reshapes immunoglobulins, particularly IgG, IgM, and IgA, driving inflammation, cellular senescence, and tissue degeneration. By dissecting B-cell dysfunction, glycosylation changes, and Fc receptor pathways, it reveals immunoglobulins as both biomarkers and potential therapeutic targets in aging.
Study highlights healthcare costs linked to both underweight and obesity in children
The NHS incurs an estimated £340 million in additional healthcare costs annually due to weight-related health problems in children – but it is not just obesity driving the costs.
Immune system found to be more mobile and flexible than previously thought
Researchers at Karolinska Institutet in Sweden have discovered that some natural killer cells, NK cells, temporarily reside in our organs and then leave them via the lymphatic system.




