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A team from Huntsman Cancer Institute at the University of Utah (the U) has found that triple-negative breast cancer is fueled by lipids and that these fatty acids are a key feature of obesity that promote tumor growth.

Researchers at the Medical University of Vienna have taken a closer look at a previously largely unknown component of the immune system: the protein molecule TRAT1 (T Cell Receptor Associated Transmembrane Adaptor 1) plays a central role in how so-called T helper cells (a specialised subgroup of immune cells) distinguish between attack and self-control - an important mechanism for restraining inflammation and preventing autoimmune diseases. The findings have recently been published in the journal Cell Communication and Signaling.

A new clinical trial co-led by researchers at FutureNeuro and RCSI University of Medicine and Health Sciences is investigating how advanced brain monitoring could improve the diagnosis and management of epilepsy.

One in four hepatologists in the United States screened positive for unhealthy alcohol use in a survey study conducted by UCLA.

The most reliable predictor of an ex-smoker's relapse isn't strong urges to smoke or low confidence in the ability to stay off tobacco – it's weariness with the efforts to remain a non-smoker, according to a new study published today in Addiction.

A new breakthrough in a rare genetic disease which causes children to age rapidly has been discovered using 'longevity genes' found in people who live exceptionally long lives - over 100 years old.

New research from the University of Delaware finds that LGBTQ+ adolescents in Delaware face strikingly higher rates of mental health challenges and substance use compared to their peers.

Will it be possible to treat severe kidney inflammation with fewer drugs in the future? A new study by the University Hospital Bonn (UKB), the University of Bonn, and the University of Hamburg gives cause for hope.

Testosterone has long been linked to risk-taking, generosity, and competitiveness. But a new large-scale study - the biggest of its kind - finds that men given testosterone made the same economic choices as those given a placebo.

An experimental gene therapy developed by researchers at UCLA, University College London and Great Ormond Street Hospital has restored and maintained immune system function in 59 of 62 children born with ADA-SCID, a rare and deadly genetic immune disorder.

Researchers reviewed the role of watermelon as a natural source of L-citrulline and its potential to improve cardiovascular health by enhancing nitric oxide production. While promising effects on blood pressure and arterial stiffness were seen in at-risk groups, long-term and dose-specific studies are still needed to confirm clinical benefits.

For patients with knee osteoarthritis, aerobic activities such as walking, cycling, or swimming are likely to be the best exercise for improving pain, function, gait performance, and quality of life, finds a study published by The BMJ today.

Sodium-glucose cotransporter-2 (SGLT-2) inhibitors used to treat type 2 diabetes are associated with an 11% lower risk of autoimmune rheumatic diseases, such as rheumatoid arthritis and lupus, compared with another group of diabetes drugs called sulfonylureas, finds a study from South Korea published by The BMJ today.

Researchers in Northern Ireland examined whether exposure to fine particulate matter (PM2.5) and nitrogen dioxide (NO₂) increases the risk of Parkinson’s disease. While no overall link was found after adjusting for confounders, younger adults under 50 showed a modest association with PM2.5, raising questions about age-related susceptibility and diagnostic misclassification.

New research by UCLA Health has identified a sex-chromosome linked gene that drives inflammation in the female brain, offering insight into why women are disproportionately affected by conditions such as Alzheimer's disease and multiple sclerosis as well as offering a potential target for intervention.

Researchers found that microplastics from everyday plastic tableware accumulate in human semen and, although not linked to semen quality in the full cohort, were associated with altered sperm parameters in specific subgroups. Experimental models confirmed that 50 nm polystyrene particles trigger autophagy and apoptosis via the FOXA1/MAP3K1/p38 pathway, impairing sperm structure and function.

A groundbreaking international study changes the view that exposure to the toxic metal lead is largely a post-industrial phenomenon.

Why are we able to recall only some of our past experiences? A new study led by Jun Nagai at the RIKEN Center for Brain Science in Japan has an answer.

People with excess body fat who build and keep muscle may be less likely to develop obesity-induced heart, liver, or kidney damage or die early, according to a new study published in The Journal of Clinical Endocrinology & Metabolism.

Lung cancer screening might be the best-kept secret in health care today. Only about 16 percent of those who are eligible in the U.S. get screened for lung cancer, but a study coming out in NEJM Catalyst on Wednesday provides a roadmap for how health systems can improve those numbers.