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New SCLC biomarkers enable advances in precision medicine approaches
A new research paper was published in Oncotarget's Volume 15 on October 11, 2024, entitled "Relationship between the expressions of DLL3, ASC1, TTF-1 and Ki-67: First steps of precision medicine at SCLC"
Emerging therapies transform autoimmune hepatitis treatment approaches
Autoimmune hepatitis (AIH) is a chronic, progressive liver disease caused by immune system dysregulation that targets the liver. If untreated, AIH can lead to severe complications, including cirrhosis and liver failure.
New guidelines emphasize non-surgical treatments for uterine fibroids
Uterine fibroids are a common condition that affects up to 80% of women in their lifetime. Nearly half of those women will experience symptoms that affect their quality of life and fertility, including severe pain and anemia.
Electric fans ease heart strain for older adults in humid heat
New collaborative research from the University of Sydney and the Montreal Heart Institute has shown that using a fan in hot and humid weather reduces cardiac strain in older people, contradicting recommendations from the Centers of Disease Control and Prevention in the US.
Five minutes of extra exercise a day could lower blood pressure, study finds
Adding small amounts of exercise into daily routine, such as climbing stairs or cycling to the shops, could help to reduce blood pressure, with just five additional minutes a day estimated to yield improvements, finds a new study from researchers at UCL and the University of Sydney.
Assessing recurrence risk with ctDNA-based MRD detection in NSCLC patients
In operable non-small cell lung cancer (NSCLC), molecular residual disease (MRD) detection via circulating tumor DNA (ctDNA) has emerged as a promising approach to identify individuals at high risk of disease recurrence and potentially guide adjuvant therapy decisions.
The global challenge of weight-related issues in kidney disease
A new nationwide study from Japan spanning a 14 year study period has revealed an increasing trend of overweight and obesity in patients with the incident end-stage kidney disease (ESKD).
Study highlights gaps in measuring sexual orientation and mental health risks
Sexual orientation-;dictated by factors like sexual identity, attraction and behavior-;is challenging to measure comprehensively.
Healthy lifestyle choices can offset genetic risk for brain diseases
Christopher D. Anderson, MD, MSc, chief of the Division of Stroke and Cerebrovascular Diseases at Brigham and Women's Hospital and associate neurologist in the Department of Neurology and Center for Genomic Medicine at Massachusetts General Hospital, is the corresponding author and Jonathan Rosand, MD, MSc, co-founder of the McCance Center for Brain Health and neurologist in the Department of Neurology and Center for Genomic Medicine at Massachusetts General Hospital, is an author of a paper published on November 6, 2024, in Neurology, the medical journal of the American Academy of Neurology, "Health-related behaviors and risk of common age-related brain diseases across severities of genetic risk."
Mount Sinai researchers uncover key process in memory integration
Mount Sinai researchers have discovered for the first time a neural mechanism for memory integration that stretches across both time and personal experience.
Understanding the role of neuroimmune cells in brain health and disease
The brain, traditionally considered an immune-privileged organ due to the blood-brain barrier (BBB), has its own sophisticated immune defense system.
Small amount of physical activity may help to lower blood pressure
New research suggests that adding a small amount of physical activity – such as uphill walking or stair-climbing – into your day may help to lower blood pressure.
Study supports very early abortion for women seeking termination
Clinics and hospitals currently defer medication abortion until ultrasound confirms a pregnancy inside the uterus.
Daytime sleepiness and low enthusiasm may be linked to motoric cognitive risk syndrome
Older people who are sleepy during the day or lack enthusiasm for activities due to sleep issues may be more likely to develop a syndrome that can lead to dementia, according to a study published in the November 6, 2024, online issue of Neurology®, the medical journal of the American Academy of Neurology.
Study links high blood sugar to thrombosis risk in diabetes
A study conducted at the Center for Research on Redox Processes in Biomedicine (Redoxoma) helps understand how high blood sugar (hyperglycemia), one of the manifestations of diabetes, can cause thrombosis.
Cachexia diagnosis criteria affect cancer patient survival rates
Maintaining good health and well-being is crucial for how well patients respond to cancer treatments. Unfortunately, cachexia, or involuntary weight loss, is a major concern for many individuals with advanced cancer.
Many veterans pursue psychedelics for healing or spiritual exploration
Most U.S. military veterans who have used psychedelics reported in a recent study that they pursued the substances for healing or spiritual exploration, and over 80% said they benefited from the experience – even those who had challenging outcomes.
Research sheds light on how fecal transplants improve gut health
In a novel study that identified male chromosome genetic material in the intestines of female patients undergoing fecal transplants, researchers at Johns Hopkins Medicine say they have significantly expanded scientific understanding of how some of these transplants may succeed and work.
Study links nasal autoantibodies to COVID-19 severity prediction
A wide variety of COVID-19 symptoms exist, ranging from mild to severe, and while current strains of the virus generally cause milder symptoms, those with co-morbidities are still at an exponentially greater risk of severe disease.
Study highlights long-term socioeconomic effects of preterm birth
By analyzing all live births in Canada over a six-year period and following children for more than two decades, researchers found that preterm births and the related cognitive, development and physical health impacts of prematurity are associated with lower income, employment and university enrollment.