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A groundbreaking study published in Hypertension, the journal of the American Heart Association, has identified a set of blood-based biomarkers that can predict improvements in blood pressure five years after adolescents underwent metabolic bariatric surgery.

Sudden cardiac death is responsible for an unusually high proportion of deaths in female bodybuilders worldwide, according to research published in the European Heart Journal today (Tuesday).

The EndObesity Consortium’s narrative review underscores that most childhood obesity risks emerge in the first 1,000 days, well before birth, highlighting gaps in parental, social, and policy interventions. Effective prevention demands preconception-focused, family-wide, and system-level strategies built on equitable public health frameworks.

Researchers in Chicago found that both mothers and fathers consumed far less DHA and EPA than recommended, with lower maternal intake linked to prior preterm birth. Socioeconomic disadvantage and neighborhood opportunity also influenced omega-3 intake, highlighting disparities that affect family health potential.

Digital health tools such as apps, wearables, and web platforms can modestly improve children’s physical activity, diet, and weight outcomes. Shorter programs boost activity, while longer ones better support weight management, though effects on sleep and sedentary time remain unclear.

Chronic alcohol use accelerates Alzheimer’s disease (AD) progression by intensifying oxidative stress, neuroinflammation, and amyloid-tau pathology through shared molecular pathways. The review highlights emerging therapies, targeting TLR4, GSK-3β, and metabolic dysfunction, that may mitigate alcohol-induced neurodegeneration.

Research shows that more daytime movement in pregnant women with hyperglycemia can raise nighttime blood sugar, highlighting the need for further investigation.

The study uncovers links between neighborhood disadvantage and Alzheimer's biomarkers, stressing the importance of addressing social inequalities in healthcare.

Increased grip strength correlates with lower obesity-related disease risk, suggesting muscle power as a key factor in preclinical obesity management.

This systematic review and meta-analysis found that while yogurt consumption shows a modest positive association with bone health markers, its effect on bone mineral density and fracture prevention in adults is clinically negligible. Current evidence is based solely on observational studies, with low certainty and limited characterization of yogurt products.

This systematic review and meta-analysis of 31 studies reveals that healthy, anti-inflammatory dietary patterns, particularly the Mediterranean and DASH diets, are linked to improved sexual function and reduced incontinence symptoms in pelvic floor dysfunction. However, prospective evidence for incontinence improvement remains limited, suggesting that benefits may be mediated by metabolic and inflammatory pathways, especially in individuals with obesity or metabolic syndrome.

This Mendelian randomization study found that low-calorie diets may slightly increase the risk of psoriatic arthritis, while vegetarian and gluten-free diets showed no causal links to psoriasis, acne, or atopic dermatitis. The findings challenge assumptions about universally beneficial dietary patterns and highlight the need for cautious interpretation of dietary interventions in inflammatory skin disease.

Researchers developed seven MRI-based biological age clocks across major organs using UK Biobank imaging, linking each to proteins, metabolites, genetics, disease risks, mortality, and cognitive decline. These organ-specific age gaps reveal how uneven aging shapes vulnerability to conditions such as diabetes, hypertension, and dementia, opening new paths for precision prevention and clinical trial stratification

Individuals with multiple long-term conditions are two and a half times more likely to die following COVID-19 infection than others.

In a landmark moment at the ESMO Congress 2025, pivotal studies have unveiled compelling evidence that a new class of anti-cancer agents-antibody-drug conjugates (ADCs)-can dramatically improve outcomes for patients with early-stage HER2-positive breast cancer.

Across the world, more than 1.5 billion people suffer from chronic liver disease. The U.S. Centers for Disease Control and Prevention reports that it kills more than 52,000 people a year in the United States alone - the ninth most common cause of death in the nation.

Plastic is ubiquitous in the modern world, and it's notorious for taking a long time to completely break down in the environment - if it ever does.

Dominika Pilat, PhD, and Ana Griciuc, PhD, of the Department of Neurology at Massachusetts General Hospital are the lead and senior authors of a paper published in Neuron, "The Gain-of-Function TREM2-T96K Mutation Increases Risk for Alzheimer's Disease by Impairing Microglial Function."

Nirupama Yechoor, MD, MSC, of the Department of Neurology at Massachusetts General Hospital, is the senior author of a paper published in JAMA Network Open, "Coherence of Stroke Survivors' Lived Experiences and the Stroke Specific Quality of Life Scale."

The European Society for Endocrinology (ESE) and the European Society for Paediatric Endocrinology (ESPE) have released today, 17 October 2025, the EndoCompass Research Roadmap: Directions for the Future of Endocrine Science.