Feed aggregator

Two complementary studies reveal how an insufficient supply of energy in macrophages, key immune cells in artery walls, drives the progression of atherosclerosis - and how this knowledge could lead to better diagnostics and future therapies.

Immune cells called B cells make antibodies that fight off invading bacteria, viruses and other foreign substances. During their preparation for this battle, B cells transiently revert to a more flexible, or plastic, stem-cell-like state in the lymph nodes, according to a new preclinical study from Weill Cornell Medicine investigators.

Children with peanut allergies may not need large doses of peanut oral immunotherapy (OIT) to build protection to peanut, finds a new study led by The Hospital for Sick Children (SickKids) and Montreal Children's Hospital. Researchers found that a small dose can help children with their peanut allergy and reduce the risk of severe reactions from accidental exposures, with less side effects than the current standard treatment.

Small cell lung cancer (SCLC) is one of the most aggressive forms of lung cancer, with a five-year survival rate of only five percent. Despite this poor prognosis, SCLC is initially highly responsive to chemotherapy.

A research team at Oregon Health & Science University has discovered a promising new drug combination that may help people with acute myeloid leukemia overcome resistance to one of the most common frontline therapies.

Harvard Medical School researchers have uncovered crucial insights into how an emerging class of antiviral drugs works.

Following stroke, some people experience a language disorder that hinders their ability to process speech sounds.

More than seven million Americans have Alzheimer's disease, and two-thirds of them are women, according to the Alzheimer's Association. The O'Banion Lab at the Del Monte Institute for Neuroscience at the University of Rochester has long been studying this disease and is looking more closely at the differences between male and female brains.

For the first time, clinicians have access to a clear, evidence-based roadmap for adjusting antiseizure medication doses during pregnancy and after childbirth.

New research from Fujita Health University reveals that talking can subtly delay the eyes’ ability to detect and stabilize on visual information.

Calcium (Ca2+) drives many cellular functions, though the way it controls quality of proteins in the endoplasmic reticulum (ER), a cellular organelle that synthesizes and transports proteins, is widely unknown.

A new study published today in Science Translational Medicine by researchers at The University of Texas MD Anderson Cancer Center details a therapeutic vulnerability in patients with an aggressive subtype of triple-negative breast cancer.

The secret to a healthier and "younger" heart lies in the vagus nerve. A recent study coordinated by the Sant'Anna School of Advanced Studies in Pisa and published in Science Translational Medicine has shown that preserving bilateral cardiac vagal innervation is an anti-aging factor.

Prescription stimulants, such as Ritalin and Adderall, are widely used to treat attention deficit hyperactivity disorder (ADHD), including in children.

Encouraging people to get vaccinated is often seen as a public health success story. However, understanding how persuading people to roll up their sleeves to receive vaccines creates social division is crucial.

A newly developed artificial intelligence (AI) model is highly accurate in predicting blood loss in patients undergoing high-volume liposuction, reports a study in the January issue of Plastic and Reconstructive Surgery, the official medical journal of the American Society of Plastic Surgeons.

Researchers at Osaka Metropolitan University have discovered a practical way to detect and fix common labeling errors in large radiographic collections. By automatically verifying body-part, projection, and rotation tags, their research improves deep-learning models used for routine clinical tasks and research projects.

Researchers have developed experimental drugs that encourage the mitochondria in our cells to work a little harder and burn more calories. The findings could open the door to new treatments for obesity and improve metabolic health.

Even a low daily intake of alcohol--just 9 g or around one standard drink-is linked to a 50% heightened risk of mouth (buccal mucosa) cancer in India, with the greatest risk associated with locally brewed alcohol, finds a large comparative study, published online in the open access journal BMJ Global Health.

For over a century, Alzheimer's disease (AD) has been considered irreversible. Consequently, research has focused on disease prevention or slowing, rather than recovery.