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Study reveals how FOXA1 mutations drive prostate cancer and therapy resistance
A new study from the University of Michigan Rogel Health Cancer Center, published in Science, sheds light on how two distinct classes of mutations in the FOXA1 gene-commonly altered in prostate cancer-drive tumor initiation formation and therapeutic resistance.
Can saffron treat Alzheimer’s and depression?
Saffron shows promise as a natural treatment for depression and cognitive decline, performing as well as standard drugs in clinical trials. However, more rigorous studies are needed before saffron can be recommended in mainstream psychiatric and dementia care.
Brain injury linked to criminal behavior in new study
A new study led by researchers at the University of Colorado Anschutz Medical Campus, Brigham and Women's Hospital and Harvard Medical School has found that damage to a specific region of the brain may contribute to criminal or violent behavior.
Fire smoke exposure found to alter immune system at the cellular level
Exposure to fire smoke-which can be composed of particulate matter, gases, materials from buildings such as perfluoroalkyl and polyfluoroalkyl substances (PFAS), toxic metals, and carcinogenic compounds-may alter the immune system on a cellular level, according to a new study led by researchers at Harvard T.H. Chan School of Public Health.
New insights into programmed cell death could offer relief for inflammatory bowel disease
New basic science insights into programmed cell death could offer relief for inflammatory bowel disease.
Study finds overlap between chemotherapy side effects and brain aging
While chemotherapy can be lifesaving, it also damages DNA and leads to cognitive issues known as "chemo brain." These effects resemble the memory and learning problems seen in older adults, prompting University of Oklahoma researchers to investigate this unique overlap of cognitive decline.
Harnessing saliva for precision medicine and early disease diagnosis
A research team led by the University of the Basque Country (Euskal Herriko Unibertsitatea, EHU) has identified hundreds of molecular markers in saliva that could reveal the risk of a person developing major diseases such as cancer, cardiovascular diseases, diabetes and neurodegenerative diseases.
Study finds multimorbidity in nearly half of hospital patients in Malawi and Tanzania
The Multilink Consortium, a NIHR-funded partnership between the Liverpool School of Tropical Medicine, the Malawi-Liverpool-Wellcome Programme, Muhimbili University of Health and Allied Sciences and Kilimanjaro Christian Medical University College, has published the first-of-its-kind research in sub-Saharan Africa to examine the scale and impact of 'multimorbidity' in patients admitted acutely to hospital.
One in four patients with chronic respiratory diseases may face catastrophic health costs in Kenya
A quarter of people seeking care for symptoms of chronic respiratory diseases in Kenya may incur 'catastrophic' health costs, new research published in The Lancet Global Health has found.
Meningiomas more common in older women than previously known
Tumors of the meninges are more common in older women than previously known. In a study from the University of Gothenburg, 2.7 percent of 70-year-old women had such tumors. The researchers emphasize that such findings should be treated with diligence and careful consideration.
Epigenetic enzyme SETD1B drives aggressive growth in acute myeloid leukemia
Acute myeloid leukemia (AML) is an aggressive cancer affecting the blood and bone marrow that progresses rapidly, making immediate treatment essential.
Sleep patterns change with geography, seasons, and daily schedules
A new international study drawing on 73 million nights of data reveals that our sleep patterns are seriously shaped by the day of the week, the season, and where we live.
Sleep deficiency worsens pain mechanisms in migraine sufferers
The mechanisms in the brain that should reduce pain don’t work as well in people with migraine when they haven’t gotten enough sleep.
Inflammatory cells may persist despite biologic therapy in severe asthma
Biological drugs have improved the lives of many people with severe asthma. However, a new study from Karolinska Institutet in Sweden shows that some immune cells with high inflammatory potential are not completely eradicated after treatment.
Earlier anticoagulant use could prevent repeat strokes in atrial fibrillation patients
Patients with atrial fibrillation who have experienced a stroke would benefit greatly from earlier treatment than is currently recommended in current UK guidelines, finds a new study led by UCL (University College London) researchers.
Sleep does not block brain response to screams and alarms
During sleep, the brain must achieve a delicate balance: disconnecting from sensory input to allow restorative functions, while remaining alert enough to wake if danger arises.
Study shows the correlation between stressed parents and self-harming in adolescents
One in ten Norwegian adolescents has engaged in deliberate self-harm without intending to commit suicide.
Surgery and speech therapy improve chronic post-stroke aphasia
Combining neck surgery with intensive speech therapy is associated with greater improvements in a person's ability to communicate after a stroke than intensive speech therapy alone, finds a clinical trial published by The BMJ today.
Ribonucleases revealed as key players in Mendelian disorders
A new review brings to light the pivotal role of ribonucleases (RNases) in shaping the molecular foundation of Mendelian disorders.
Living in disadvantaged neighborhoods linked to Alzheimer’s biomarkers
People living in more disadvantaged neighborhoods may be more likely to have biomarkers for inflammation and Alzheimer's disease, according to a study published June 25, 2025, in Neurology, the medical journal of the American Academy of Neurology.