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Scientists rethink GLP-1 delivery to improve dosing, tolerability, and adherence

Rss Feed - Wed, 05/27/2026 - 23:29
The review highlights nanocarriers, microspheres, hydrogels, microneedles, long-acting formulations, and co-formulations as promising but mostly early-stage strategies that still require stronger long-term clinical evidence.

How do everyday spices help protect the heart?

Rss Feed - Wed, 05/27/2026 - 22:53
A Nutrition Reviews supplement article reviewed controlled studies showing that culinary spice and herb blends may improve selected cardiometabolic risk markers, including post-meal triglycerides, insulin responses, inflammation, endothelial function, and 24-hour blood pressure. The review also highlighted exploratory evidence that spices and herbs may influence immune-cell activity, circulating phytochemical metabolites, and gut bacterial composition, while emphasizing the need for longer and more diverse studies.

Study explores alternatives to clinical trials in rural healthcare research

Rss Feed - Wed, 05/27/2026 - 22:40
Randomized controlled trials (RCTs) are challenging to conduct in rural areas, however, a new Griffith University study examined how high-quality research could be conducted when RCTs were not possible.

Tobacco price cap could raise billions and improve public health

Rss Feed - Wed, 05/27/2026 - 22:31
The UK could raise up to £4.9 billion over five years and significantly improve public health by capping tobacco prices and increasing taxes.

Traditional medicinal plant extract shows promising anti-skin aging effects

Rss Feed - Wed, 05/27/2026 - 22:16
Announcing a new publication for Acta Materia Medica journal. Vicatia thibetica de Boiss (V. thibetica), a traditional medicinal and edible plant used by the Bai ethnic group in China, is known for its effects in tonifying qi, nourishing the blood, dispelling dampness, and relieving itching.

Lactylation may drive pulmonary fibrosis through metabolic reprogramming pathways

Rss Feed - Wed, 05/27/2026 - 22:14
Announcing a new article publication in BIO Integration. Pulmonary fibrosis (PF) is a progressive and irreversible interstitial lung disease that is characterized by destruction of alveolar architecture, excessive proliferation of fibroblasts, and aberrant deposition of extracellular matrix (ECM) but the precise pathogenesis has yet to be fully elucidated.

Early pregnancy interventions improve healthy gestational weight gain outcomes

Rss Feed - Wed, 05/27/2026 - 22:10
Both too little and too much weight gain during pregnancy are associated with serious maternal and child health outcomes, including preterm birth, low birth weight, death, preeclampsia, and unplanned cesarean delivery.

Vaginal bromocriptine may ease pain and heavy bleeding in adenomyosis

Rss Feed - Wed, 05/27/2026 - 22:06
A pilot randomized controlled trial found that vaginal bromocriptine reduced menstrual bleeding, pelvic pain, menstrual duration, and cycle irregularity in women with adenomyosis compared with routine treatment.

Study finds lower Alzheimer’s pathology in Black and Hispanic patients

Rss Feed - Wed, 05/27/2026 - 22:05
A large multisite study of older people with cognitive impairment finds that Black and Hispanic people, while known to be far more apt to have dementia, are significantly less apt than other racial and ethnic groups to show Alzheimer's pathology on brain scans.

Major trial compares surgical approaches for treating Chiari malformation and syringomyelia

Rss Feed - Wed, 05/27/2026 - 21:58
A nationwide study has shed new light on how to most effectively and safely treat Chiari malformation and syringomyelia, rare neurological diseases that impact both children and young adults.

New mathematical model tracks microbial contribution to human digestion

Rss Feed - Wed, 05/27/2026 - 21:53
Food labels make calories seem simple. They show the number of calories per serving, which is calculated based on how much fat, carbohydrates and protein the food contains.

Study reveals inequities in wastewater-based disease outbreak detection systems

Rss Feed - Wed, 05/27/2026 - 21:39
Wastewater surveillance was hailed during the COVID-19 pandemic as a more equitable way to track disease.

Ghrelin rises in depression despite obesity’s usual appetite-hormone suppression

Rss Feed - Wed, 05/27/2026 - 21:33
Researchers found that both acylated and deacylated ghrelin were elevated in unmedicated adults with major depressive disorder and obesity compared with non-depressed adults with obesity. The cross-sectional findings suggest ghrelin-system dysregulation may be linked to depression in obesity, but larger longitudinal studies are needed to test whether ghrelin is a reliable biomarker.

Artificial intelligence reveals hidden fluid flow patterns in sleeping brains

Rss Feed - Wed, 05/27/2026 - 21:19
When a person goes into deep sleep, waterlike fluid circulates around the brain, washing away metabolic waste that is linked to diseases such as Alzheimer's.

Aging immune system may destabilize the gut microbiome balance

Rss Feed - Wed, 05/27/2026 - 21:07
Why does the gut microbiome lose its balance as we age? Researchers at the Leibniz Institute on Aging - Fritz Lipmann Institute (FLI) in Jena now present a new explanation in a paper published in "PLoS Biology".

Heart health before pandemic influenced severity of COVID-19 infections

Rss Feed - Wed, 05/27/2026 - 21:01
Better heart health before the pandemic was linked to a lower risk of severe COVID-19 events, according to research published today in the Journal of the American Heart Association, an open-access, peer-reviewed journal of the American Heart Association.

Smaller nanoplastics trigger stronger changes in brain neuron activity

Rss Feed - Wed, 05/27/2026 - 20:55
Smaller plastic particles have more effects on neurons, the key information processing cells of the brain, new research from the University of Eastern Finland shows.

Can AI help build a fairer food system from farm to plate?

Rss Feed - Wed, 05/27/2026 - 20:45
AI could help make food systems more personalized and climate-resilient by linking nutrition, health, farming, logistics, and sustainability data. The review highlights promise in precision nutrition, vertical farming, traceability, and smarter supply chains, while warning that privacy, equity, energy use, data silos, and governance gaps must be addressed.

Study suggests new potentially druggable ways to target GPCR signaling

Rss Feed - Wed, 05/27/2026 - 13:33
A study published in Nature by researchers at Duke University School of Medicine identifies a new way that G protein–coupled receptors (GPCRs) - targets of roughly one-third of FDA-approved drugs - control signaling in cells.

True toll of long COVID may be double that of current estimates, research shows

Rss Feed - Wed, 05/27/2026 - 13:26
The true toll of long COVID may be double that of current estimates and hidden from current surveillance systems that rely on capturing diagnostic codes, according to new research led by Mass General Brigham.

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