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Scientists used Mendelian randomisation to explore the two-way relationship between gut microbiota and insomnia, analyzing GWAS data from over 386,000 individuals and two major microbiome cohorts. The study found only limited taxa surviving strict correction, suggesting small but causal links that highlight the gut–brain axis in sleep health.

A Cochrane review assessed ketamine and other NMDA receptor antagonists for chronic non-cancer pain. The evidence was low to very low certainty, showing no clear pain relief and potential adverse effects with intravenous ketamine.

Researchers developed and validated an AI-based nutrition recommendation system (AINR) that generates weekly Mediterranean meal plans tailored to individual needs and dietary restrictions. Tested on 4,000 simulated users, the system achieved high accuracy in calorie and nutrient targets but struggled with profiles involving milk and nut allergies.

Researchers show that countries with higher initial COVID-19 vaccine acceptance also achieved stronger booster uptake, but trust and access remain decisive. The commentary warns that vaccine successes also fueled hesitancy, demanding structural reforms, clear communication, and proactive strategies to protect immunization.

Finnish researchers found that differences in maternal and infant gut microbiota during the first weeks of life were linked to the risk of respiratory tract infections in the first six months. Specific bacteria, including butyrate producers and opportunistic pathogens, may shape early infection susceptibility.

A new international study led by researchers at Moffitt Cancer Center, the Karolinska Institutet and the University of Texas MD Anderson Cancer Center has uncovered a surprising mechanism of resistance to immunotherapy: cancer's ability to injure nearby nerves.

The COVID-19 virus hijacks the machinery of testicular cells that produce the hormone testosterone in order to replicate.

New research, published today in the journal Science, shows how lysosomes - organelles that act like cells' waste disposal system - respond to stress by becoming abnormally bloated, a process called lysosomal vacuolation that is associated with numerous diseases.

When a disease-causing virus or other organism is transmitted from one species to another, most of the time the infection sputters and dies out.

Scientists at St. Jude Children's Research Hospital demonstrated for the first time that the protein midkine plays a preventative role against Alzheimer's disease.

A new study by USC Leonard Davis School of Gerontology researchers shows that Americans with less education are aging faster than their peers with more schooling, and the gap has grown over the last 30 years.

A new study looks at the physical forces that help shape developing organs. Scientists in the past believed that the fast-acting biochemistry of genes and proteins is responsible for directing this choreography.

For much of the 20th century it was thought that the adult brain was incapable of regeneration. This view has since shifted dramatically and neurogenesis – the birth of new neurons – is now a widely accepted phenomenon in the adult brain, offering promising avenues for treating many neurological conditions.

Researchers have discovered that a virus living inside the fungus Aspergillus fumigatus significantly boosts the fungus's ability to survive stress and cause severe infections in mammals.

Transthyretin amyloidosis (ATTR) is caused by the misfolding and aggregation of the transthyretin (TTR) protein, leading to multi-organ damage.

University of Arizona researchers devised a new method to deliver cancer chemotherapy drugs to pancreatic and breast cancer tumors more effectively and with less damage to healthy tissues than standard forms of chemotherapy.

New research from the University of Pittsburgh School of Medicine and Cambridge University upends a long-standing belief about brain plasticity.

Australian researchers have used an innovative genome-wide screening approach to identify genes, and their encoded proteins, that play critical roles in the prevention of lymphoma development, revealing new potential treatment targets for these blood cancers.

A preclinical evaluation of a new 'dual-mode' tracer agent shows promise in not only helping surgeons image and plan prostate cancer procedures, but also provide them with much more consistent and targeted guidance during surgery.

Using vaginal estrogen tablets was not associated with an increased risk of recurrent ischemic stroke among postmenopausal women in a registry in Denmark, according to research published today in Stroke, the peer-reviewed scientific journal of the American Stroke Association, a division of the American Heart Association.