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E. coli genomic analysis uncovers antibiotic resistance mechanisms in dogs

Rss Feed - Tue, 07/16/2024 - 13:03
Researchers studying antimicrobial-resistant E. coli – the leading cause of human death due to antimicrobial resistance worldwide – have identified a mechanism in dogs that may render multiple antibiotic classes ineffective.

Ultrasound techniques for the surveillance, diagnosis, and treatment of hepatocellular carcinoma

Rss Feed - Tue, 07/16/2024 - 12:50
Hepatocellular carcinoma (HCC) is a primary malignancy of the liver and one of the leading causes of cancer-related deaths worldwide. Early detection and accurate diagnosis are crucial for effective management and improved survival rates.

New approaches for repairing the function of mutated proteins that cause stroke

Rss Feed - Tue, 07/16/2024 - 12:46
Cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy (CARASIL) is a rare, severe, and deadly genetic disorder characterized by damage to small blood vessels in the brain and which triggers strokes.

Researchers reveal unique characteristics of previously unexplored protein FAM110A

Rss Feed - Tue, 07/16/2024 - 12:42
An international research collaboration, led by Prof. Dr. Robert Grosse (Centre for Integrative Biological Signalling Studies and Institute of Clinical and Experimental Pharmacology and Toxicology, University of Freiburg), Dr. Libor Macurek (Institute of Molecular Genetics, Czech Academy of Sciences, Prague) and Dr. Zdenek Lansky (Institute of Biotechnology, Czech Academy of Sciences, Prague) has uncovered a new mechanism of the crosstalk between microtubules and actin cytoskeleton during cell division and revealed unique characteristics of the previously unexplored protein FAM110A.

Early detection of specific microRNAs may help predict preeclampsia in pregnant women

Rss Feed - Tue, 07/16/2024 - 12:13
Preeclampsia (PE) is a significant contributor to the increase in maternal morbidity and mortality worldwide, with particularly alarming numbers in the United States, where it affects about 2–8% of pregnancies, resulting in premature birth with associated morbidities for their infants as well.

Study suggests switching from smoking to vaping indoors may reduce children’s secondhand exposure to nicotine

Rss Feed - Tue, 07/16/2024 - 07:54
Researchers compared nicotine absorption among children exposed to secondhand tobacco smoke, secondhand vapor, and those with no exposure.

What is the association of Mediterranean diet–based interventions with cardiometabolic biomarkers in children and adolescents?

Rss Feed - Tue, 07/16/2024 - 07:11
Researchers reviewed and meta-analyzed the randomized clinical trials (RCTs) assessing the effects of Mediterranean diet -based interventions on cardiometabolic biomarkers in children and adolescents.

UChicago expands microbiome research capabilities with new manufacturing facility

Rss Feed - Tue, 07/16/2024 - 05:46
The Duchossois Family Institute (DFI) at the University of Chicago can manufacture clinical-grade encapsulated bacteria – catalyzing opportunities to better understand the microbiome and its myriad of roles in human health.

Chronic Urticaria: Addressing unmet needs, emerging therapies, and advances in personalized treatment approaches

Rss Feed - Tue, 07/16/2024 - 05:24
Emerging personalized treatment approaches for chronic urticari.

Omega-3 fatty acids found to significantly reduce acne in new study

Rss Feed - Tue, 07/16/2024 - 00:46
Recent research highlights that omega-3 fatty acids significantly reduce acne severity. Supplementation and a Mediterranean diet improved skin condition in most study participants.

Study shows oral semaglutide matches DPP-4i in adherence and persistence for type 2 diabetes

Rss Feed - Tue, 07/16/2024 - 00:33
Researchers found that adherence and persistence in T2D patients using oral semaglutide is similar to DPP-4i, but semaglutide users required fewer concurrent medications, indicating higher long-term efficacy.

Does being obese or overweight reduce semen quality?

Rss Feed - Tue, 07/16/2024 - 00:09
Researchers in China found significant associations between obesity and reduced semen quality in men, with the greatest declines in those with severe obesity. The study emphasizes the importance of maintaining a healthy weight for male reproductive health.

Harnessing brain proteins for enhanced diabetes and weight-loss drugs

Rss Feed - Mon, 07/15/2024 - 23:51
A network of proteins found in the central nervous system could be harnessed to increase the effectiveness and reduce the side effects of popular diabetes and weight-loss drugs, according to new research from the University of Michigan.

Low-GI Mediterranean diet boosts quality of life but not sleep in diabetes-prone adults

Rss Feed - Mon, 07/15/2024 - 23:48
Researchers found that a low-glycemic index Mediterranean diet improves some aspects of health-related quality of life but not sleep in adults at risk for type 2 diabetes.

Immune protein C1q impacts neuronal protein synthesis in the aging brain, study reveals

Rss Feed - Mon, 07/15/2024 - 23:46
A groundbreaking study conducted at the lab of Beth Stevens, PhD, at Boston Children's Hospital has revealed that an immune protein impacts neuronal protein synthesis in the aging brain.

Discovery of "unconventional" immune response opens new avenue in TB vaccine development

Rss Feed - Mon, 07/15/2024 - 23:29
An "unconventional" immune response now identified by scientists from the Hackensack Meridian Center for Discovery and Innovation (CDI) is a potential new pathway for developing new vaccines for tuberculosis (TB), according to a new publication.

Research reveals optimal magnesium levels could lower dementia risk

Rss Feed - Mon, 07/15/2024 - 23:29
Researchers found moderate evidence of a U-shaped link between serum magnesium levels and dementia, but more studies are needed to clarify magnesium's role in cognitive health.

Tulane University leads effort in sex-based precision medicine with NIH grant

Rss Feed - Mon, 07/15/2024 - 23:25
If a man and a woman each suffer a heart attack, you may assume the symptoms and diagnoses should be the same.

Researchers discover key functions of IRF1 in cancer progression and treatment response

Rss Feed - Mon, 07/15/2024 - 23:08
Investigators at the UCLA Health Jonsson Comprehensive Cancer Center have uncovered new details about the role of a protein called interferon regulatory factor (IRF1) in cancer progression and treatment response, offering new insight that can potentially help improve the effectiveness of cancer immunotherapy.

Children in deprived areas face higher risk of severe tooth decay requiring hospital extraction

Rss Feed - Mon, 07/15/2024 - 23:03
Researchers at Queen Mary University of London have found that children living in areas with high levels of deprivation are three times more likely to have severe tooth decay that requires a dental extraction in hospital, compared with children living in more affluent areas.

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