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New study reveals brain clearance of toxins is reduced during sleep and anesthesia

Rss Feed - Wed, 05/15/2024 - 07:25
The adipose-neural axis plays an important role in arrhythmogenesis.

Genetic link identified between inflammatory bowel disease and Parkinson's disease

Rss Feed - Wed, 05/15/2024 - 06:31
The researchers found, as expected from prior studies that LRRK2 is associated with IBD-PD and discovered new associations as well.

Single measles jab up to 2.6 times more likely to be ineffective in C-section born children

Rss Feed - Wed, 05/15/2024 - 05:41
The dynamics of measles immunity at birth and following vaccination.

Streamlining immune sensing and signaling dynamics research with INTEGRA Biosciences liquid handling tools

Rss Feed - Wed, 05/15/2024 - 03:18
Immunologists in the Immune Sensing and Signaling Dynamics Group | ImmunoHUB at Instituto de Investigação e Inovação em Saúde (i3S) in Porto, Portugal, are using INTEGRA Biosciences laboratory tools to help further our understanding of the human immune system.

Optibrium partners with FMC Corporation to transform agrochemical discovery

Rss Feed - Wed, 05/15/2024 - 03:17
Optibrium, a leading developer of software and AI solutions for drug discovery, has signed a license agreement for its AI-powered discovery platform, Cerella™, with FMC Corporation (FMC), a global leader in crop protection.

Study finds 41% of people with long-term itchiness have fatigue

Rss Feed - Wed, 05/15/2024 - 03:02
41% of people with long-term itchiness have fatigue, likely due to persistent sleep disruption, according to new research published in the British Journal of Dermatology. In comparison, only 22% of the control group had fatigue.

New study identifies 17 genes driving clonal hematopoiesis in aging blood cells

Rss Feed - Wed, 05/15/2024 - 02:59
Scientists have discovered 17 additional genes that drive the abnormal overgrowth of mutated blood cells as we age. The findings, published today (14 May) in Nature Genetics, provide a more complete view of the genetic factors behind clonal hematopoiesis – a process associated with ageing and linked to increased risks of blood cancers.

More than 20,000 volunteers join effort to accelerate dementia drug development

Rss Feed - Wed, 05/15/2024 - 02:57
More than 20,000 volunteers have been recruited to a resource aimed at speeding up the development of much-needed dementia drugs. The cohort will enable scientists in universities and industry to involve healthy individuals in clinical trials to test whether new drugs can slow the decline in various brain functions including memory and delay the onset of dementia.

Metabolomics study finds biomarkers predicting autism in newborns

Rss Feed - Tue, 05/14/2024 - 23:59
A study in Communications Biology utilized metabolomics in newborns to identify markers that might predict autism spectrum disorder (ASD), finding distinct metabolic profiles in children with ASD compared to typically developing children.

Sleep and anesthesia hinder brain toxin clearance, study reveals

Rss Feed - Tue, 05/14/2024 - 23:22
Researchers found that brain clearance is reduced during both sleep and anesthesia, contradicting the belief that these states enhance toxin removal.

Interactions between adipose and sympathetic neurons contribute to cardiac arrhythmia

Rss Feed - Tue, 05/14/2024 - 22:57
A study in Cell Reports Medicine used an in vitro co-culture of adipocytes, cardiomyocytes, and sympathetic neurons to reveal that the adipose-neural axis plays a crucial role in arrhythmogenesis, driven by interactions between epicardial adipose tissue and the sympathetic nervous system.

Semaglutide shows significant weight loss and health benefits in four-year obesity study

Rss Feed - Tue, 05/14/2024 - 22:16
A study in Nature Medicine evaluated the effects of semaglutide on weight and anthropometric outcomes in adults with obesity but without diabetes, finding significant weight loss and improved health metrics over four years. The study also highlighted the safety and tolerability of semaglutide across different BMI categories.

Paddling through mental health: Long-term benefits of SUP revealed in "Freedom on Water" study

Rss Feed - Tue, 05/14/2024 - 21:43
A study in the journal Healthcare highlights the significant long-term benefits of stand-up paddling (SUP) on mental health and well-being for individuals with mental disorders, as seen in the "Freedom on Water" project.

Study proposes a novel therapeutic avenue for tackling EHF-induced cholangiocarcinogenesis

Rss Feed - Tue, 05/14/2024 - 17:03
This study is led by Dr. Yiming Luo (Hepatic Surgery Centre, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology) and Professor. Huifang Liang (Hepatic Surgery Centre, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology).

Pharmacological treatment reduces specific crimes in adolescents with ADHD

Rss Feed - Tue, 05/14/2024 - 16:39
A study in the Journal of the American Academy of Child and Adolescent Psychiatry (JAACAP), published by Elsevier, found that pharmacological treatment of attention-deficit/hyperactivity disorder (ADHD) reduced violence- and public-order related crimes.

Human cell-based model of thoracic aortic aneurysm offers new opportunities for drug development

Rss Feed - Tue, 05/14/2024 - 16:23
Using human cells in laboratory rats, Michigan Medicine researchers have developed a functional model of thoracic aortic aneurysm, creating opportunities for more effective understanding of disease development and treatments for the potentially fatal condition, a study suggests.

The power of reflecting on teenage years for mental health and resilience

Rss Feed - Tue, 05/14/2024 - 16:17
Asking young adults to advise their younger selves could have a positive impact on their self-esteem, resilience and mental health, according to a new study from the University of Surrey.

Racial and ethnic disparities in Alzheimer's diagnosis and CNS drug prescription

Rss Feed - Tue, 05/14/2024 - 16:03
Compared to Black and Asian people, white and Hispanic people with Alzheimer's disease and related dementias were most likely to be diagnosed with symptoms like depression and agitation, according to a new study from the USC Schaeffer Center for Health Policy & Economics.

Experts advocate for terminology change in brain injury research

Rss Feed - Tue, 05/14/2024 - 15:56
A new editorial published this May in the British Journal of Sports Medicine by experts from Spaulding Rehabilitation, Boston University, Mayo Clinic, and the Concussion Legacy Foundation, argues that the term "subconcussion" is a dangerous misnomer that should be retired.

New mechanism discovered to weaken pseudomonas aeruginosa virulence

Rss Feed - Tue, 05/14/2024 - 15:22
The opportunistic bacterial pathogen Pseudomonas aeruginosa is dangerous due to its resistance to multiple antibiotics.