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Innovative malaria prodrug targets liver, enhances efficacy while reducing toxicity, preclinical studies show
Tafenoquine, a prodrug that could fulfill the criteria for a mass eradication campaign.
New QR4 algorithm outperforms previous models in predicting cardiovascular disease risk
A new cardiovascular risk prediction algorithm.
Depression linked to chronic pain: Variability shown across patient characteristics
The factors influencing the variability in depression prevalence among chronic pain sufferers.
Replacing dinner calcium with breakfast intake could reduce heart disease risk, study finds
The quantity of calcium consumed at breakfast and dinner was associated with cardiovascular disease (CVD).
US study links extended sitting and lack of coffee to higher death rates
The independent and combined effects of daily sedentary times and coffee consumption on cardiovascular disease.
New models improve heart disease risk prediction, especially for women
When it comes to matters of the heart, cardiovascular disease in women is underdiagnosed compared to men. A popular scoring system used to estimate how likely a person is to develop a cardiovascular disease within the next 10 years is the Framingham Risk Score. It is based on factors including age, sex, cholesterol levels, and blood pressure.
Rising costs fuel quit-smoking surge in England amid health advice dip
Researchers investigate the factors that motivate smokers to quit smoking to ultimately determine the influence of COVID-19 on smoking cessation.
The hidden struggle of lateropulsion in stroke survivors
Lateropulsion, a clinical condition which results in the body leaning to one side, affects about half of all stroke survivors.
Longitudinal multi-omics monitoring paves the way for early pancreatic cancer diagnosis
A new case report published in the peer-reviewed OMICS: A Journal of Integrative Biology describes how longitudinal multi-omics monitoring (LMOM) helped to detect a precancerous pancreatic tumor and led to a successful surgical intervention.
New tool hunts for Alzheimer's clues in gut microbiome
Cleveland Clinic researchers are using artificial intelligence to uncover the link between the gut microbiome and Alzheimer's disease.
The vital role of therapeutic alliances in psychedelic treatment
Drug effects have dominated the national conversation about psychedelics for medical treatment, but a new study suggests that when it comes to reducing depression with psychedelic-assisted therapy, what matters most is a strong relationship between the therapist and study participant.
Risks of antipsychotic use in dementia extend beyond previous alerts, study shows
Antipsychotic use in people with dementia is associated with higher risks of a wide range of serious health outcomes compared with non-use, according to a new study from a collaboration across the Universities of Manchester, Nottingham, Edinburgh and Dundee.
Review: Facilitators and barriers to vaccination uptake in pregnancy
Researchers from St George’s, University of London have identified key barriers to vaccine uptake for whooping cough, flu and Covid-19 in pregnant women, and outline recommendations for addressing vaccine hesitancy. The results are from the first review of its kind and published today in the journal PLOS ONE.
Healthy plant-based diets cut mortality risks for Spain's seniors
A study spanning 12 years reveals that moderate adherence to a healthful pro-vegetarian diet significantly reduces mortality risks from cardiovascular disease and all causes among Spanish adults over 65.
UniSA research highlights key pain concepts for managing pelvic pain
A new study from the University of South Australia is putting people’s experiences of pelvic pain at the front of pain education to develop better pain management strategies and improved outcomes.
Study shows meth users have lower empathy and higher aggression, ecstasy users show normal empathy but more impulsive aggression
A study in the European Neuropsychopharmacology journal finds that methamphetamine users show lower empathy and higher aggression, whereas ecstasy (MDMA) users exhibit increased impulsive aggression but normal empathy levels.
Minimally invasive techniques fight colorectal cancer precursors
Colorectal cancer (CRC) is the second most common cancer in the United States. This highlights the importance of early detection and treatment of precancerous lesions like large polyps. Endoscopy offers a minimally invasive approach to removing these polyps, reducing the need for traditional surgery.
Higher zinc intake linked to lower asthma risk in overweight kids
A study in the World Allergy Organization Journal reveals that higher dietary zinc intake is linked to a lower risk of asthma in overweight or obese children and adolescents, indicating zinc's potential role in asthma prevention in this group.
Study reveals avocado may lower diabetes risk in women, not men
A recent study in the Journal of the Academy of Nutrition and Dietetics found that avocado consumption is associated with a reduced risk of diabetes in Mexican women, but not in men, highlighting potential gender-specific dietary benefits.
Large-scale study identifies new approach to early Alzheimer's detection
Digital memory test and a blood sample - this combination will be tested for its potential to identify early Alzheimer's disease in a new research study. Over a hundred healthcare centers are part of the study that is now inviting participants to sign up. At least 3,000, preferably many more participants are needed for the study to be successful.
